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The map label for this gene is uup-A

Identifier: 52842223

GI number: 52842223

Start: 2245044

End: 2246900

Strand: Reverse

Name: uup-A

Synonym: lpg2006

Alternate gene names: 52842223

Gene position: 2246900-2245044 (Counterclockwise)

Preceding gene: 52842224

Following gene: 52842222

Centisome position: 66.13

GC content: 39.8

Gene sequence:

>1857_bases
TTGATGAGTATAGTTTCCCTTAACGGTGCCTCTTTAATCTTGGCTGGCAATTGTATTCTGGACCGTGCAGATTTACAGAT
TCAGCCACAGGATAGAATTGCTCTTGTTGGACGCAATGGCGCTGGAAAATCAACATTGCTGAAAATACTACAAGGCGAGT
TGGTGCTTGATGGTGGACAAATTCAACGCTCATCCGGCTTGCGTATTGCTGGTTTAGTTCAGGAAGTCCCAAGTGCTGAG
GGAGAGTCAGTGTACCATTTTCTTGTTAAAAGCTTAGGTGAAACAGGGGAAGTATTGTCCCAGTTTCATGAGTTTACGAA
ACAAGGAGATATGGACAAATTGGCCAAATGTCAGCAGCGAATGGACAACTTGAATGCATGGCATTTATTACCTGAAATTG
AAACGATGGCAAGCCGATTGGGAATAGATATTCATGAGCAGATGTCTAATCTCTCAGGCGGTATGAAACGACGCGTATTA
TTAGGTGCGGCACTGCTTGCCAAGCCTGATTTATTGTTACTGGATGAACCTACCAACCACTTGGATGTCGAAGCAATTGA
ATGGCTAGAGAATTATTTAAAATCCTTTTCTGGTGCTGTAATAGTAGTAACTCACGACAGGGAATTCTTAAGCCAGATAG
CAACAAGCATCCTTGAAATCGATCGTGGAAAATTGTATCTACACCATTGTAATTATGAAGCTTACCTTGACAGGCGTGAA
TCGATAAGGCTTAGCGAACAAAAACAAAATGATTTGTTTGACAAACGGCTTGCAGAAGAAGAAGCCTGGATACGTACAGG
TATCAAGGCAAGACGCACACGTAATGAGGGCAGAGTCAGGGCCTTAAAGGCAATGAGAGAGCAGTACAAAGCACGTCGTA
ATCAATTAGGAACAGTGAAATCCTTAAATTTGGATGTAAGCCGTTCTGGTGCTCTTGTAGTAGAAGCAAACAAAGTGAGT
TATACAATTAATGACAAGCCCATTATAAAAGATTTTTCTTTATTAATGACAAGAGGAGACAAGCTTGGGATTATCGGCCC
CAATGGTTGTGGCAAAACCACTTTAGTTCGATTACTTCTGGGAGAAATTAAGCCTGATGCTGGAACTATAAAATTAGGGA
CAGGGCTTCAGGTAGCCTATTTTGATCAGTTACGCCGACATTTGCTTGAAGATCAAACAGTCATGTTTAATGTGGGGGAA
GGGGCTGATTATGTAACAATTAATGGTAAGCAAAAACATGTTGCCAGTTATTTGAAAGAGTTTTTATTTTCCTCTGATCG
ATTTAATCAGCCAGTATCTTCCTTGTCTGGAGGGGAAAGAAACAGATTATTACTGGCAAAACTTTTTGCCAAACCGGTTA
ATTTACTCGTAATGGATGAACCAACTAATGATTTGGATATAGAAACTCTGGAACTTCTTGAAGCTGTATTAGCTGATTAT
CCTGGTACTTTAATACTAATCAGTCATGATAGAGCGTTTATTAATCAAGTAGTAACCAGTGTGTTGGTTTATGAAGGAAA
TGGTAAGTTTAATGAATTTGTTGGTGGTTATGACGATTATAAAAAACATCAATTAACACGAAATGAGCAGCAAACGAAAT
CTCCAGTTTCAAAACGGAGCAGCCCAGAGAAAGCCAAAAATTTATCTTTTAATGAACAACGTGAGTTATCGAAGTTGCCG
CAACAGATTGAAGCCGTAGAGAAAAAAATTGAAGCACTGCATTCGCAAATGGCCTCACCTGAATTTTATCAGCAAGATGC
CAAGCTTATTTCAGAGGTAACTCAGCTGTTAGCCAAGGAAGAGGCATTGTTAAATCAATATTTTGCTCGATGGGAAGAGC
TGGAAGAGAAAAAATAA

Upstream 100 bases:

>100_bases
TATGATTCAGCAGGGCAAACAATTGATATTAAAAAGACAGTGAACTGACTGTATGTTTTCAATAAAATGAGATCAAACAG
ATTTATTTAAATAGAGAGTT

Downstream 100 bases:

>100_bases
AAAAGTATTTGGTTAATTGATAAGTTAAAGTGAAAAACAATAAAAAGATATCTTTAAATAAAATTAAAAATAGGATTTAA
AATGCTTTTAACCTTGGCTT

Product: ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MMSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDGGQIQRSSGLRIAGLVQEVPSAE
GESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLAKCQQRMDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVL
LGAALLAKPDLLLLDEPTNHLDVEAIEWLENYLKSFSGAVIVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRE
SIRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKSLNLDVSRSGALVVEANKVS
YTINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLGEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGE
GADYVTINGKQKHVASYLKEFLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADY
PGTLILISHDRAFINQVVTSVLVYEGNGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSSPEKAKNLSFNEQRELSKLP
QQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEEALLNQYFARWEELEEKK

Sequences:

>Translated_618_residues
MMSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDGGQIQRSSGLRIAGLVQEVPSAE
GESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLAKCQQRMDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVL
LGAALLAKPDLLLLDEPTNHLDVEAIEWLENYLKSFSGAVIVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRE
SIRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKSLNLDVSRSGALVVEANKVS
YTINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLGEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGE
GADYVTINGKQKHVASYLKEFLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADY
PGTLILISHDRAFINQVVTSVLVYEGNGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSSPEKAKNLSFNEQRELSKLP
QQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEEALLNQYFARWEELEEKK
>Mature_618_residues
MMSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDGGQIQRSSGLRIAGLVQEVPSAE
GESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLAKCQQRMDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVL
LGAALLAKPDLLLLDEPTNHLDVEAIEWLENYLKSFSGAVIVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRE
SIRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKSLNLDVSRSGALVVEANKVS
YTINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLGEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGE
GADYVTINGKQKHVASYLKEFLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADY
PGTLILISHDRAFINQVVTSVLVYEGNGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSSPEKAKNLSFNEQRELSKLP
QQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEEALLNQYFARWEELEEKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=28.9224952741021, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI10947135, Length=553, Percent_Identity=27.4864376130199, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI69354671, Length=553, Percent_Identity=27.4864376130199, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI10947137, Length=535, Percent_Identity=26.5420560747664, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI27881506, Length=535, Percent_Identity=26.5420560747664, Blast_Score=167, Evalue=4e-41,
Organism=Escherichia coli, GI1787182, Length=640, Percent_Identity=47.5, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI2367384, Length=534, Percent_Identity=36.7041198501873, Blast_Score=316, Evalue=4e-87,
Organism=Escherichia coli, GI1789751, Length=587, Percent_Identity=29.8126064735945, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI1787041, Length=506, Percent_Identity=32.2134387351779, Blast_Score=252, Evalue=6e-68,
Organism=Escherichia coli, GI1788506, Length=531, Percent_Identity=25.0470809792844, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788165, Length=186, Percent_Identity=31.1827956989247, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787758, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787029, Length=240, Percent_Identity=25.4166666666667, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=28.7081339712919, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081791, Length=242, Percent_Identity=26.8595041322314, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081782, Length=184, Percent_Identity=29.8913043478261, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=176, Percent_Identity=30.1136363636364, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786319, Length=231, Percent_Identity=28.1385281385281, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787164, Length=199, Percent_Identity=27.1356783919598, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789963, Length=223, Percent_Identity=29.1479820627803, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=192, Percent_Identity=31.7708333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787089, Length=226, Percent_Identity=26.1061946902655, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI145693107, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI48994883, Length=205, Percent_Identity=29.7560975609756, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786872, Length=213, Percent_Identity=25.8215962441315, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=545, Percent_Identity=26.0550458715596, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17555318, Length=543, Percent_Identity=26.7034990791897, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17553372, Length=554, Percent_Identity=29.2418772563177, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71992290, Length=253, Percent_Identity=25.6916996047431, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=553, Percent_Identity=25.6781193490054, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321121, Length=550, Percent_Identity=26.5454545454545, Blast_Score=163, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6325030, Length=378, Percent_Identity=28.042328042328, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=376, Percent_Identity=25, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324314, Length=378, Percent_Identity=25.6613756613757, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324985, Length=176, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666836, Length=534, Percent_Identity=29.7752808988764, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24642252, Length=552, Percent_Identity=27.8985507246377, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI18859989, Length=552, Percent_Identity=27.8985507246377, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24641342, Length=552, Percent_Identity=29.1666666666667, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI281363262, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653245, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69489; Mature: 69489

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDGGQ
CCEEEEECCCEEEEECCEEEECCCCEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCC
IQRSSGLRIAGLVQEVPSAEGESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLAKCQQR
EECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHH
MDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLLGAALLAKPDLLLLDEPTNH
HHCCCCEEECHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCC
LDVEAIEWLENYLKSFSGAVIVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRE
CCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCHHH
SIRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVK
HCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEE
SLNLDVSRSGALVVEANKVSYTINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLL
EECEEECCCCEEEEEECEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
GEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEGADYVTINGKQKHVASYLKE
HHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHHHHHH
FLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADY
HHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
PGTLILISHDRAFINQVVTSVLVYEGNGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRS
CCEEEEEECCHHHHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHCCCHHHHHCCHHHCC
SPEKAKNLSFNEQRELSKLPQQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKE
CCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EALLNQYFARWEELEEKK
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDGGQ
CCEEEEECCCEEEEECCEEEECCCCEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCC
IQRSSGLRIAGLVQEVPSAEGESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLAKCQQR
EECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHH
MDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLLGAALLAKPDLLLLDEPTNH
HHCCCCEEECHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCC
LDVEAIEWLENYLKSFSGAVIVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRE
CCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCHHH
SIRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVK
HCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEE
SLNLDVSRSGALVVEANKVSYTINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLL
EECEEECCCCEEEEEECEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
GEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEGADYVTINGKQKHVASYLKE
HHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHHHHHH
FLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADY
HHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
PGTLILISHDRAFINQVVTSVLVYEGNGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRS
CCEEEEEECCHHHHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHCCCHHHHHCCHHHCC
SPEKAKNLSFNEQRELSKLPQQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKE
CCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EALLNQYFARWEELEEKK
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]