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The map label for this gene is kdsB

Identifier: 52842137

GI number: 52842137

Start: 2142611

End: 2143363

Strand: Reverse

Name: kdsB

Synonym: lpg1919

Alternate gene names: 52842137

Gene position: 2143363-2142611 (Counterclockwise)

Preceding gene: 52842138

Following gene: 52842136

Centisome position: 63.08

GC content: 40.9

Gene sequence:

>753_bases
ATGAGCCATAATTTTCATGTGATTATACCAGCCAGATATCATTCCAGTCGTTTTCCAGGTAAATTACTTCAGGAAATTAA
CGGTATTACCGTGATTGAACGAGTTTACAGGCAAGCACTTCTGGCAGAACCAAAGTCGGTGATTATTGCCACTGATCATG
ATGAGATAGCTGACCGCGCAATCCAATTTGGAGCGGAGGTTGTAATCACTTCACATACGCACCAAACTGGAACTGATCGA
ATTGCGGAGGTTATCGCCAAAGGTAGCTTTGCTCCTGATGACGTCATTGTCAATGTGCAAGGTGATGAGCCATTTATCCG
ACCCAAATTAATTCAACAAGTTGCTTGCTCTTTAACAAAGACAAAGGCGCCTGTGTCTACTTTATGCTGGCCTATTAGCA
GCCTTGAAATATTAAATAACCCTAATGTGGTTAAAGTGGTATGCACTCGAGATAATCACGCTCTTTATTTTTCAAGAAGC
GCGATACCTTTTCACAGAGATGATAAAAACGCTTATTCCAATACCTTCAGGCATATCGGTTTATATGCTTATCGTGCTGC
CTTTTTACTGGAATTTGTTAGCTGGCCGCCCTGCACCTTGGAACAAATAGAGTGTTTGGAGCAATTGCGCATCCTATGGT
CAGGTTTTTCTATCCGGGTTGATGAGGCCTGCGAAGAACCTTTACAGGATATTAATACAAAAGAAGATTTGATTTTGGCT
CAGCAATATTTTCTTGATACTTTCAATGTATAA

Upstream 100 bases:

>100_bases
TCTGCAAATTTGATAGGCTGGCATTTCCTGTTCGTGATGATATTCCTGTAATGCTGGAACAAGAAGCGCGTTTGATTCCT
CTGGAAGAGAAAGATAAATT

Downstream 100 bases:

>100_bases
CTCGTTGTAATTTATTGTTTTTTCTATGAGAATGATTTTATTCACTCCGTATGGTCGCCACTCAATTTTCATCATAATGG
AGTGACGATCTTGACTATTT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVIAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRS
AIPFHRDDKNAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
QQYFLDTFNV

Sequences:

>Translated_250_residues
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVIAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRS
AIPFHRDDKNAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
QQYFLDTFNV
>Mature_249_residues
SHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDRI
AEVIAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRSA
IPFHRDDKNAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILAQ
QYFLDTFNV

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=239, Percent_Identity=46.8619246861925, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28352; Mature: 28220

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRA
CCCCEEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
IQFGAEVVITSHTHQTGTDRIAEVIAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTK
HHCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
TKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRSAIPFHRDDKNAYSNTFRHIG
CCCCHHHHHHCCCHHHCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
LYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHH
QQYFLDTFNV
HHHHHHHCCC
>Mature Secondary Structure 
SHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRA
CCCEEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
IQFGAEVVITSHTHQTGTDRIAEVIAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTK
HHCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
TKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRSAIPFHRDDKNAYSNTFRHIG
CCCCHHHHHHCCCHHHCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
LYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHH
QQYFLDTFNV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA