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The map label for this gene is pfp [H]

Identifier: 52842131

GI number: 52842131

Start: 2136427

End: 2137671

Strand: Direct

Name: pfp [H]

Synonym: lpg1913

Alternate gene names: 52842131

Gene position: 2136427-2137671 (Clockwise)

Preceding gene: 52842130

Following gene: 52842134

Centisome position: 62.88

GC content: 43.69

Gene sequence:

>1245_bases
ATGTCAGTTAAAAATGCAATCTACGCCCAGTCTGGTGGTGTGACCGCTGTAATTAATGCATCCGCTTGTGGTGTCATCCA
AACCGCCAAACTATTTCCAGAGCAAATTGGTAAAGTTTATGCTGCAAAAAATGGCATTATCGGTGCCTTAAACGAGGAAT
TAATCGATACTTCATTGGAAAGTGAAGAAGACATTGCCAAATTGATGCAAACTCCTTCCGGAGCTTTTGGCTCCTGCCGC
TACAAATTAAAAGACAATGGTGAAGAGTATCAACGCTTAATCGCTGTCTTCAAGGCCCACAACATAGGCTATTTCTTTTA
CAATGGCGGCGGGGACTCACAAGATACTGCCCATAAAGTATCCCAGTTAGGTAAAACCATGGGCTATCCTATTACCTGCA
TAGGTATCCCTAAAACAGTAGATAACGATCTGCCTTTTACAGACAATTGCCCGGGGTTTGGATCAGTCGCGAAATACATT
GCCATTTCAACGAAGGAAGCTGGTTTTGATGTCGCGTCCATGGCGGCTTCATCGACGAAAGTGTTTATTCTTGAGGTGAT
GGGAAGGCATGCAGGCTGGATAGCTGCGGCTAGTGGGCTGGCCGAGCAAAATCCAGGCGAACCGCCACACATTATTCTAT
TACCTGAGGTTCCTTTTGAGCCAACTCGTTTTCTAAAAAAAGTGAAGGACTGTGTCAATTCATATGGTTATTGTGTGATT
GTTGTTTCAGAAGGTATCCGCAATAAGGAAGGAAAATTTCTCAGTGAAGCAGGATTACGTGATGCATTCGGACATGCTCA
ATTAGGTGGTGTTGCACCTGTCATCGCTCAATTAATTAAATCTGAACTGGGTTTTAAATATCATTGGGCAGTTGCAGATT
ATCTTCAACGGGCAGCCAGGCACATAGCCTCGCAAACTGATTTGGATCAAGCTTACGCTTTAGGTAAAGCTGCTGTGGAA
TATGCCGTTAAAGGATATAACGCGATTATGCCTGTTGTCATTCGTGAGCAGGACGAACCCTATCAATGGTCTATAGGCCA
AGTCCCTCTGGCTGAGGTAGCTAACCAGGAAAAGGCTATGCCGCCAGAGTATATAGCTGAAGATGGCATGGGAATTACGG
ACGCATGCAAACGTTACTTGTCCCCTTTGATTCAAGGTGAAGCTTATCCAAATTACAAAAATGGATTGCCAGATTATGTC
CGACTAAAAAACCAGTTAGTGGCTAAAAAAATCAACCAAGATTAA

Upstream 100 bases:

>100_bases
ATAATATTTAATGAAATAAGGCCATAAAAACTCTCTTGTATGAAAACCAAAGTAAAAGTCTGTATCAACCTAATAAAATC
ATTCTAGTTATGGAGACAAA

Downstream 100 bases:

>100_bases
GGGCGGCAGTAGGCTGGACGATATTTACTAATCAGGGTACCACCAGTGCAATCCCAAGTGAGTATTCTGTTAGTGGCATC
TATTGTGGGAACCATTGTAA

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLESEEDIAKLMQTPSGAFGSCR
YKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKVSQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYI
AISTKEAGFDVASMAASSTKVFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAARHIASQTDLDQAYALGKAAVE
YAVKGYNAIMPVVIREQDEPYQWSIGQVPLAEVANQEKAMPPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYV
RLKNQLVAKKINQD

Sequences:

>Translated_414_residues
MSVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLESEEDIAKLMQTPSGAFGSCR
YKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKVSQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYI
AISTKEAGFDVASMAASSTKVFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAARHIASQTDLDQAYALGKAAVE
YAVKGYNAIMPVVIREQDEPYQWSIGQVPLAEVANQEKAMPPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYV
RLKNQLVAKKINQD
>Mature_413_residues
SVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLESEEDIAKLMQTPSGAFGSCRY
KLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKVSQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYIA
ISTKEAGFDVASMAASSTKVFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVIV
VSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAARHIASQTDLDQAYALGKAAVEY
AVKGYNAIMPVVIREQDEPYQWSIGQVPLAEVANQEKAMPPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYVR
LKNQLVAKKINQD

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=286, Percent_Identity=25.1748251748252, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 44893; Mature: 44761

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLE
CCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCC
SEEDIAKLMQTPSGAFGSCRYKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKV
CHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
SQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYIAISTKEAGFDVASMAASSTK
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHCCCCC
VFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
EEEEEHHCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAAR
EEECCCCCCCCCHHHHCCCHHHCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
HIASQTDLDQAYALGKAAVEYAVKGYNAIMPVVIREQDEPYQWSIGQVPLAEVANQEKAM
HHHHHCCHHHHHHHHHHHHHHHHHCCCCEECEEEECCCCCCEEECCCCCHHHHCCCCCCC
PPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYVRLKNQLVAKKINQD
CHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLE
CCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCC
SEEDIAKLMQTPSGAFGSCRYKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKV
CHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
SQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYIAISTKEAGFDVASMAASSTK
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHCCCCC
VFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
EEEEEHHCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAAR
EEECCCCCCCCCHHHHCCCHHHCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
HIASQTDLDQAYALGKAAVEYAVKGYNAIMPVVIREQDEPYQWSIGQVPLAEVANQEKAM
HHHHHCCHHHHHHHHHHHHHHHHHCCCCEECEEEECCCCCCEEECCCCCHHHHCCCCCCC
PPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYVRLKNQLVAKKINQD
CHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10913106 [H]