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The map label for this gene is clpX

Identifier: 52842085

GI number: 52842085

Start: 2082800

End: 2084080

Strand: Reverse

Name: clpX

Synonym: lpg1860

Alternate gene names: 52842085

Gene position: 2084080-2082800 (Counterclockwise)

Preceding gene: 52842086

Following gene: 52842084

Centisome position: 61.34

GC content: 37.78

Gene sequence:

>1281_bases
TTGGTTATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGT
AAAAAAATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTTTGTAATGATATTATTCGAGAAGAGA
CGCATGAAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATA
GGGCAACAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGG
TGTTGAGCTCGGCAAAAGTAATATTTTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGC
GGATTCTTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGCGAAGACGTTGAAAAT
ATTATCCAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGA
TAAGATTTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAAT
TAATTGAAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAGGTAGATACA
TCAAATATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCAAGCAT
AGGTTTTTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATG
ATTTAATTAAATATGGGTTGATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCG
GCATTGATTGATATATTAACGAGACCTAAGAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGA
ACTTGAGTTTAGAGGCGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGAT
CAATACTTGAAAATATTCTTTTAGACACTATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAG
AGTGTAGTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTA
A

Upstream 100 bases:

>100_bases
TATAAGTTGGTTTGATAGTAATGTGGTGGCGCAATATTATCTGATTGTCTAAAATTTTACATGTAATTACTATTAATTAG
TAATAGCTGTAAGAAGGGGT

Downstream 100 bases:

>100_bases
GTAAGATGTTGACTTCTGCAATAATTTAAATTGTTGCAGAAGTTATTTTATCTTTCATTCACAAAATATATTTAAAGCTG
ATTTTGTAGCTTAAAATAAC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MVMSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVI
GQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDT
SNILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEA
ALIDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDE
SVVNGLSKPILIYEQDEKKSASGSKD

Sequences:

>Translated_426_residues
MVMSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVI
GQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDT
SNILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEA
ALIDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDE
SVVNGLSKPILIYEQDEKKSASGSKD
>Mature_426_residues
MVMSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVI
GQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDT
SNILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEA
ALIDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDE
SVVNGLSKPILIYEQDEKKSASGSKD

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=331, Percent_Identity=51.6616314199396, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786642, Length=423, Percent_Identity=76.1229314420804, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=99, Percent_Identity=46.4646464646465, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=295, Percent_Identity=48.8135593220339, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=295, Percent_Identity=48.8135593220339, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.8746803069054, Blast_Score=251, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=40.6374501992032, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=429, Percent_Identity=39.8601398601399, Blast_Score=280, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24648289, Length=340, Percent_Identity=45.8823529411765, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24648291, Length=340, Percent_Identity=45.8823529411765, Blast_Score=291, Evalue=7e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46814; Mature: 46814

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEE
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TEARLPTPKEISNFLDEYVIGQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGP
HHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEC
TGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQQGI
CCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDT
EEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
SNILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGL
CCEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCC
IPEFVGRLPVVTTLQELDEAALIDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAK
CHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
KALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESVVNGLSKPILIYEQDEKKS
HHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECHHHHHCCCCCEEEEECCCCCC
ASGSKD
CCCCCC
>Mature Secondary Structure
MVMSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEE
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TEARLPTPKEISNFLDEYVIGQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGP
HHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEC
TGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQQGI
CCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDT
EEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
SNILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGL
CCEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCC
IPEFVGRLPVVTTLQELDEAALIDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAK
CHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
KALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESVVNGLSKPILIYEQDEKKS
HHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECHHHHHCCCCCEEEEECCCCCC
ASGSKD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA