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The map label for this gene is hupB

Identifier: 52842083

GI number: 52842083

Start: 2079705

End: 2080007

Strand: Reverse

Name: hupB

Synonym: lpg1858

Alternate gene names: 52842083

Gene position: 2080007-2079705 (Counterclockwise)

Preceding gene: 52842084

Following gene: 52842082

Centisome position: 61.22

GC content: 39.27

Gene sequence:

>303_bases
ATGATTAACTGTAAAGGGGAAAAGATGAATAAGAGTGAATTAGTTGATGCTATAGCAAGCGGTTCAGGTTTGACCAAAGC
TGACGCAAGCAGAGTTCTTGAAACTTTTATGGCTACTGTAACTGATGTCTTAAAGAAAGGCGATCAAGTTGTAATACCTG
GTTTTGGTTCTTTTTCAACAGGTAATCGTTCAGCACGTACTGGCAGAAACCCACAGACTGGAAAAACAATCCAAATTAAA
GCGTCACGGGTTGCCAAATTTAAAGCAGGTAAAAACCTGAAAGAAGCGGTACAACAAGCTTAA

Upstream 100 bases:

>100_bases
GAGTATATTTCTCTTCGTGGCCCGCTACTGGCGGGCTCTGCAAGGATGTACGAACTTGACTGGAGCAGTTGAATCTGTTT
AAATCAGCTCCGGAATATGG

Downstream 100 bases:

>100_bases
GTTTTCAGGGTGCTTAGCTCAGCTGGGAGAGCATCGCCCTTACAAGGCGAGGGTCGTAGGTTCGATCCCTACAGCACCCA
CCAAGAAATGGAGTGGTAGT

Product: hypothetical protein

Products: NA

Alternate protein names: HU-1; NS1 [H]

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MINCKGEKMNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTGRNPQTGKTIQIK
ASRVAKFKAGKNLKEAVQQA

Sequences:

>Translated_100_residues
MINCKGEKMNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTGRNPQTGKTIQIK
ASRVAKFKAGKNLKEAVQQA
>Mature_100_residues
MINCKGEKMNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTGRNPQTGKTIQIK
ASRVAKFKAGKNLKEAVQQA

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=56.1797752808989, Blast_Score=105, Evalue=6e-25,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=50, Blast_Score=93, Evalue=3e-21,
Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=38.0434782608696, Blast_Score=75, Evalue=7e-16,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=38.4615384615385, Blast_Score=65, Evalue=6e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10587; Mature: 10587

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINCKGEKMNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFST
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
GNRSARTGRNPQTGKTIQIKASRVAKFKAGKNLKEAVQQA
CCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MINCKGEKMNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFST
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
GNRSARTGRNPQTGKTIQIKASRVAKFKAGKNLKEAVQQA
CCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550432 [H]