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The map label for this gene is yfhC

Identifier: 52841949

GI number: 52841949

Start: 1919230

End: 1919655

Strand: Reverse

Name: yfhC

Synonym: lpg1721

Alternate gene names: 52841949

Gene position: 1919655-1919230 (Counterclockwise)

Preceding gene: 52841950

Following gene: 52841946

Centisome position: 56.5

GC content: 42.25

Gene sequence:

>426_bases
ATGCAACTGGCTTACGAGCAAGCGGTTATAGCTCGTAATGAAGGAGAGGTTCCTGTTGGGGCTGTGTTGGTTAGCAAAGA
CAATCAATTATTAGGCGTTGGCAGAAATGTCATTGAAAAAAGTCATGATCCTTCTGATCATGCTGAAATCAGGGCAATAC
GACAAGCCTCGAGAAAGTTAAATAATCATAGATTATTGGATACAACGCTTTATGTTACTCTTGAGCCCTGTGTGATGTGT
GCGGGACTTATGGTTCACGCACGCATCAAACGGCTGGTATTTGCTACCCGAGATTTTAAAACAGGGGCAGCTGGCTCAAT
GTTTAATGTTTTACATGCTCTAAACCATTCGGTATTAATAGACGAAGGCATTATGCAGGCTGAGTGTTCTCAATTGCTGT
CAGATTTTTTCAGAAACCTTCGCTAG

Upstream 100 bases:

>100_bases
ATCGAATTATTAATGAAGTAGAGGGAGTATCACGTGTCACTTACGATATTTCTGGCAAGCCACCTGCTACCATTGAATGG
GAATGATTGATAAATTTTGG

Downstream 100 bases:

>100_bases
TAATTTATCTTGGCATATTTCTTAATACTTGCTTTTAGAAATTTCCAAAATTAATTTTTCTTTTAAAATTGTTTTTTCCT
CATGATTCAGGGAATAACCT

Product: deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVTLEPCVMC
AGLMVHARIKRLVFATRDFKTGAAGSMFNVLHALNHSVLIDEGIMQAECSQLLSDFFRNLR

Sequences:

>Translated_141_residues
MQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVTLEPCVMC
AGLMVHARIKRLVFATRDFKTGAAGSMFNVLHALNHSVLIDEGIMQAECSQLLSDFFRNLR
>Mature_141_residues
MQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVTLEPCVMC
AGLMVHARIKRLVFATRDFKTGAAGSMFNVLHALNHSVLIDEGIMQAECSQLLSDFFRNLR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=119, Percent_Identity=34.453781512605, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=57.3426573426573, Blast_Score=156, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17541138, Length=144, Percent_Identity=31.25, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=35.4166666666667, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=139, Percent_Identity=32.3741007194245, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=151, Percent_Identity=31.1258278145695, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=30.3448275862069, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15697; Mature: 15697

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKL
CCCCHHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHCCCCCCHHHHHHHHHHHHHHH
NNHRLLDTTLYVTLEPCVMCAGLMVHARIKRLVFATRDFKTGAAGSMFNVLHALNHSVLI
CCCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEE
DEGIMQAECSQLLSDFFRNLR
CCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKL
CCCCHHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHCCCCCCHHHHHHHHHHHHHHH
NNHRLLDTTLYVTLEPCVMCAGLMVHARIKRLVFATRDFKTGAAGSMFNVLHALNHSVLI
CCCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEE
DEGIMQAECSQLLSDFFRNLR
CCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]