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The map label for this gene is yrbE [H]

Identifier: 52841880

GI number: 52841880

Start: 1826195

End: 1827199

Strand: Reverse

Name: yrbE [H]

Synonym: lpg1652

Alternate gene names: 52841880

Gene position: 1827199-1826195 (Counterclockwise)

Preceding gene: 52841881

Following gene: 52841879

Centisome position: 53.78

GC content: 39.8

Gene sequence:

>1005_bases
ATGAAAAAGAAAATATGTCGAATTGGGATAGTAGGTGCGGGAAGAATTGGTAGACTGCACGCAGAAAATATTCTATTTCA
TTTACCGCAATTTGAATTAGTGGCCATAGCAGATCCCCAGATCGATAGGAATTGGGCAGAAAAATTAGGGATTGCAATCG
CGTCTACTCAATCAGAAGATGTGCTATGCCACCCTGACTTGGATGCCATCTTGATCGCGTCACCATCTCATTTACATCTC
GAACAAATTATTACAGCGAGTATTCATGAGAAAGCGATTTTTTGTGAAAAACCAATTGGTTTGAATGAAGAAGAGATAGA
GAAAACATTAAACATAATCAAAAACAATAATACTTTATTGCAACTTGGATTCAATCGTCGATTTGATCCAGGTTTTGCCA
ACATTCAGAAAAGAGTGCAGTTTGGTGAAATTGGCACTCCTCATATTCTTCGAATTACTTCTCGTGATCCGGCTTGTCCA
TCCAAAGAATATTGCGCGACATCTGGTGGAATATTTATGGACATGTCTATTCATGATTTTGATATGGCACGTTTTTTAAT
GCAATCCGAGGTTGTGGAGGTTTATGCAACAGGGGCTGTTCTAATTAATCCTGATTTTGAGCAGTTTGATGATGTAGATA
CAGCAATCATTCAACTACGGTTCGCTAATGGCGCATTTGGTGTCATAGATAACAGCCGTCAAGCAATCTATGGGTATGAT
CAAAGGATAGAAGTATTCGGTTCAGGTGGTATGTTATTGGCTGAAAATCAGTTTGAGCATACGGTATCTCGATACTCGGC
TAATGGAACGGATGGCGCAAAACCTCAATATTTTTTCCTTGAGCGTTATCATCAAGCTTATCTGGCAGAACTGAATGCGT
TTTATAGTGCCTGGAATGATAATCAGACAAGTCCCGTTTCAGGATTGGATGGACTACAAGCCTTGCGCATCGCAAAAGCA
GCGAAACAATCTTTAGAAACGCATCTGCCAGTAGTATTGAGTTGA

Upstream 100 bases:

>100_bases
TGGAAGAAAATTTAAGCTCTGGAAAAAAAGTAAGAGATATAGGTCAACCAGTATCGAAAAATATAAAAATAGCAAAATTT
AATTTAATTATGGATTAATC

Downstream 100 bases:

>100_bases
GGCCGCTATGAAACAGTTTCCCGGATTTTATTTTGATAAGAATAGAGCAATCGATTTGATTTGTATGGGACGCGTAGCAG
TTGATCTCTACGCGGAGCAA

Product: myo-inositol-2-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKKKICRIGIVGAGRIGRLHAENILFHLPQFELVAIADPQIDRNWAEKLGIAIASTQSEDVLCHPDLDAILIASPSHLHL
EQIITASIHEKAIFCEKPIGLNEEEIEKTLNIIKNNNTLLQLGFNRRFDPGFANIQKRVQFGEIGTPHILRITSRDPACP
SKEYCATSGGIFMDMSIHDFDMARFLMQSEVVEVYATGAVLINPDFEQFDDVDTAIIQLRFANGAFGVIDNSRQAIYGYD
QRIEVFGSGGMLLAENQFEHTVSRYSANGTDGAKPQYFFLERYHQAYLAELNAFYSAWNDNQTSPVSGLDGLQALRIAKA
AKQSLETHLPVVLS

Sequences:

>Translated_334_residues
MKKKICRIGIVGAGRIGRLHAENILFHLPQFELVAIADPQIDRNWAEKLGIAIASTQSEDVLCHPDLDAILIASPSHLHL
EQIITASIHEKAIFCEKPIGLNEEEIEKTLNIIKNNNTLLQLGFNRRFDPGFANIQKRVQFGEIGTPHILRITSRDPACP
SKEYCATSGGIFMDMSIHDFDMARFLMQSEVVEVYATGAVLINPDFEQFDDVDTAIIQLRFANGAFGVIDNSRQAIYGYD
QRIEVFGSGGMLLAENQFEHTVSRYSANGTDGAKPQYFFLERYHQAYLAELNAFYSAWNDNQTSPVSGLDGLQALRIAKA
AKQSLETHLPVVLS
>Mature_334_residues
MKKKICRIGIVGAGRIGRLHAENILFHLPQFELVAIADPQIDRNWAEKLGIAIASTQSEDVLCHPDLDAILIASPSHLHL
EQIITASIHEKAIFCEKPIGLNEEEIEKTLNIIKNNNTLLQLGFNRRFDPGFANIQKRVQFGEIGTPHILRITSRDPACP
SKEYCATSGGIFMDMSIHDFDMARFLMQSEVVEVYATGAVLINPDFEQFDDVDTAIIQLRFANGAFGVIDNSRQAIYGYD
QRIEVFGSGGMLLAENQFEHTVSRYSANGTDGAKPQYFFLERYHQAYLAELNAFYSAWNDNQTSPVSGLDGLQALRIAKA
AKQSLETHLPVVLS

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=230, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37227; Mature: 37227

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKICRIGIVGAGRIGRLHAENILFHLPQFELVAIADPQIDRNWAEKLGIAIASTQSED
CCCCEEEEEEECCCCCCEEEHHHHEEECCCEEEEEEECCCCCHHHHHHHCEEEECCCCCC
VLCHPDLDAILIASPSHLHLEQIITASIHEKAIFCEKPIGLNEEEIEKTLNIIKNNNTLL
EEECCCCCEEEEECCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHCCCCEEE
QLGFNRRFDPGFANIQKRVQFGEIGTPHILRITSRDPACPSKEYCATSGGIFMDMSIHDF
EECCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCCEEEEEEECHH
DMARFLMQSEVVEVYATGAVLINPDFEQFDDVDTAIIQLRFANGAFGVIDNSRQAIYGYD
HHHHHHHHHHHHEEEECCEEEECCCHHHHCCCCEEEEEEEECCCEEEEEECCCCEEECCC
QRIEVFGSGGMLLAENQFEHTVSRYSANGTDGAKPQYFFLERYHQAYLAELNAFYSAWND
CEEEEEECCCEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NQTSPVSGLDGLQALRIAKAAKQSLETHLPVVLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure
MKKKICRIGIVGAGRIGRLHAENILFHLPQFELVAIADPQIDRNWAEKLGIAIASTQSED
CCCCEEEEEEECCCCCCEEEHHHHEEECCCEEEEEEECCCCCHHHHHHHCEEEECCCCCC
VLCHPDLDAILIASPSHLHLEQIITASIHEKAIFCEKPIGLNEEEIEKTLNIIKNNNTLL
EEECCCCCEEEEECCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHCCCCEEE
QLGFNRRFDPGFANIQKRVQFGEIGTPHILRITSRDPACPSKEYCATSGGIFMDMSIHDF
EECCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCCEEEEEEECHH
DMARFLMQSEVVEVYATGAVLINPDFEQFDDVDTAIIQLRFANGAFGVIDNSRQAIYGYD
HHHHHHHHHHHHEEEECCEEEECCCHHHHCCCCEEEEEEEECCCEEEEEECCCCEEECCC
QRIEVFGSGGMLLAENQFEHTVSRYSANGTDGAKPQYFFLERYHQAYLAELNAFYSAWND
CEEEEEECCCEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NQTSPVSGLDGLQALRIAKAAKQSLETHLPVVLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]