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The map label for this gene is hlyD [H]

Identifier: 52841747

GI number: 52841747

Start: 1678858

End: 1679994

Strand: Direct

Name: hlyD [H]

Synonym: lpg1517

Alternate gene names: 52841747

Gene position: 1678858-1679994 (Clockwise)

Preceding gene: 52841746

Following gene: 52841748

Centisome position: 49.41

GC content: 35.71

Gene sequence:

>1137_bases
ATGAAAAAAACTCACAGCTCAAAAACCTTTACCCATATTATCTTATGGACTTCCTTGCTTTTTTTTATTGTAGCAATTAT
TTGGGCTAATTATGCCATTCTTGATGAAGTAACTACAGGACAAGGAAAAGTAATTCCCTCTAGTGAGGTTCAGGTCATAC
AGAATCTTGAAGGCGGGATTATTCAGAATATTTTTGTCAAAGAAGGGCAAATAGTTAAAAAAGATCAAATTTTAATGCAA
ATCGATAATACTCGGTTTATGGCCAGCTATGCCGAAGCAGAGAAAAAAATTGATGCATTGGAAATAGAAATTATAAGGCT
TAATGCTGAAATTAGTGATACAAAACCTGTGTTTCCAGATAAATTTATCAAAACCTATCCTCATCTTGTGCAGGATCAGT
TGTCTCTGTATGAATCACGGATGAGAGAGTTGAATCAACTGAAAAAATCCCTAGAGTTGGCGCAAAAAGAATTGGATTTA
ACTCGTCCATTATTAAAGGGTGGATCCGTTTCAGAAGTAGAGGTTATTCGTCTGGAAAGATCAGTAAGTGAAATTAAAGG
AAACATTGAGAAGTTCAAATCAGAAGAACTGGATAAATTGAATAAAGCCAGAACAGAGTTGTTTGCGCTGATTGAGGCCA
ATAAAGCGGATAAAGATCGTTTAACAAGGACCACAGTTCGTTCTCCAGTTTATGGTATTGTAAAACAAATTAAGACGACA
ACGATTGGTGGTGTAGTTCAACCAGGTAGTGATTTACTTGAGATAGTCCCGCTTGATGATACTTTATTAATTGAAGCAAA
AATACGCCCTTCTGATATTGGTTTTATACACCCAGGCCAAAAAGCGATGGTTAAAATTACTGCTTATGACTTTTCTATCT
ATGGTGGATTGGAGGGTGTTGTAGAGCATATTAGTGCCGATACTATTATTGATGAGAAAACAGATAAAAAAGAAGAAAGC
TACTATATAGTGAAAGTGCGAACAGATAAAAATTATCTGGGAACTGAAAAAAAGCCATTGCCTATCATTCCTGGCATGCA
AGCCACGGTTGATATACTTACAGGTCAAAAATCTGTTCTTCAATACCTCTTGAAACCTATCATTAAAGCTAAGCAATCAG
CACTAAGAGAACGTTGA

Upstream 100 bases:

>100_bases
TCGTATTATCGTTTTGGAAAATGGCAAAATCATTGCTGATGGTAATAAAGAAGCTGTTCTAAGCGCCCTTAGGACAGGGG
TAACGGTGAGGAAATAGTCT

Downstream 100 bases:

>100_bases
TTATTAGAAGTCCTTAACTTGTTATATTATGCGATAATTAGTTAATTGGTCTATTATAATATTAATATTATTTTCTGTAA
GGCTATCTGTGCAAAGGATA

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKKTHSSKTFTHIILWTSLLFFIVAIIWANYAILDEVTTGQGKVIPSSEVQVIQNLEGGIIQNIFVKEGQIVKKDQILMQ
IDNTRFMASYAEAEKKIDALEIEIIRLNAEISDTKPVFPDKFIKTYPHLVQDQLSLYESRMRELNQLKKSLELAQKELDL
TRPLLKGGSVSEVEVIRLERSVSEIKGNIEKFKSEELDKLNKARTELFALIEANKADKDRLTRTTVRSPVYGIVKQIKTT
TIGGVVQPGSDLLEIVPLDDTLLIEAKIRPSDIGFIHPGQKAMVKITAYDFSIYGGLEGVVEHISADTIIDEKTDKKEES
YYIVKVRTDKNYLGTEKKPLPIIPGMQATVDILTGQKSVLQYLLKPIIKAKQSALRER

Sequences:

>Translated_378_residues
MKKTHSSKTFTHIILWTSLLFFIVAIIWANYAILDEVTTGQGKVIPSSEVQVIQNLEGGIIQNIFVKEGQIVKKDQILMQ
IDNTRFMASYAEAEKKIDALEIEIIRLNAEISDTKPVFPDKFIKTYPHLVQDQLSLYESRMRELNQLKKSLELAQKELDL
TRPLLKGGSVSEVEVIRLERSVSEIKGNIEKFKSEELDKLNKARTELFALIEANKADKDRLTRTTVRSPVYGIVKQIKTT
TIGGVVQPGSDLLEIVPLDDTLLIEAKIRPSDIGFIHPGQKAMVKITAYDFSIYGGLEGVVEHISADTIIDEKTDKKEES
YYIVKVRTDKNYLGTEKKPLPIIPGMQATVDILTGQKSVLQYLLKPIIKAKQSALRER
>Mature_378_residues
MKKTHSSKTFTHIILWTSLLFFIVAIIWANYAILDEVTTGQGKVIPSSEVQVIQNLEGGIIQNIFVKEGQIVKKDQILMQ
IDNTRFMASYAEAEKKIDALEIEIIRLNAEISDTKPVFPDKFIKTYPHLVQDQLSLYESRMRELNQLKKSLELAQKELDL
TRPLLKGGSVSEVEVIRLERSVSEIKGNIEKFKSEELDKLNKARTELFALIEANKADKDRLTRTTVRSPVYGIVKQIKTT
TIGGVVQPGSDLLEIVPLDDTLLIEAKIRPSDIGFIHPGQKAMVKITAYDFSIYGGLEGVVEHISADTIIDEKTDKKEES
YYIVKVRTDKNYLGTEKKPLPIIPGMQATVDILTGQKSVLQYLLKPIIKAKQSALRER

Specific function: Involved in the transport of hemolysin A [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42682; Mature: 42682

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTHSSKTFTHIILWTSLLFFIVAIIWANYAILDEVTTGQGKVIPSSEVQVIQNLEGGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCH
IQNIFVKEGQIVKKDQILMQIDNTRFMASYAEAEKKIDALEIEIIRLNAEISDTKPVFPD
HHHHHCCCCCEEECCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCH
KFIKTYPHLVQDQLSLYESRMRELNQLKKSLELAQKELDLTRPLLKGGSVSEVEVIRLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SVSEIKGNIEKFKSEELDKLNKARTELFALIEANKADKDRLTRTTVRSPVYGIVKQIKTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TIGGVVQPGSDLLEIVPLDDTLLIEAKIRPSDIGFIHPGQKAMVKITAYDFSIYGGLEGV
HCCCEECCCCCEEEEEECCCEEEEEEEECCCCCCEECCCCCEEEEEEEEEEEECCCHHHH
VEHISADTIIDEKTDKKEESYYIVKVRTDKNYLGTEKKPLPIIPGMQATVDILTGQKSVL
HHHHHHCHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHH
QYLLKPIIKAKQSALRER
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTHSSKTFTHIILWTSLLFFIVAIIWANYAILDEVTTGQGKVIPSSEVQVIQNLEGGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCH
IQNIFVKEGQIVKKDQILMQIDNTRFMASYAEAEKKIDALEIEIIRLNAEISDTKPVFPD
HHHHHCCCCCEEECCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCH
KFIKTYPHLVQDQLSLYESRMRELNQLKKSLELAQKELDLTRPLLKGGSVSEVEVIRLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SVSEIKGNIEKFKSEELDKLNKARTELFALIEANKADKDRLTRTTVRSPVYGIVKQIKTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TIGGVVQPGSDLLEIVPLDDTLLIEAKIRPSDIGFIHPGQKAMVKITAYDFSIYGGLEGV
HCCCEECCCCCEEEEEECCCEEEEEEEECCCCCCEECCCCCEEEEEEEEEEEECCCHHHH
VEHISADTIIDEKTDKKEESYYIVKVRTDKNYLGTEKKPLPIIPGMQATVDILTGQKSVL
HHHHHHCHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHH
QYLLKPIIKAKQSALRER
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3891743; 1495479 [H]