| Definition | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome. |
|---|---|
| Accession | NC_002942 |
| Length | 3,397,754 |
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The map label for this gene is aceE
Identifier: 52841734
GI number: 52841734
Start: 1663729
End: 1666410
Strand: Reverse
Name: aceE
Synonym: lpg1504
Alternate gene names: 52841734
Gene position: 1666410-1663729 (Counterclockwise)
Preceding gene: 52841735
Following gene: 161723253
Centisome position: 49.04
GC content: 40.53
Gene sequence:
>2682_bases TTGTTGGGGAACTATTTCATGACCAATGAAACAAATTTAGATCTGGATCCAATAGAAACTCGTGAATGGCTGGATGCCCT ACAAGCTGTACTCTTTAATGATGGTCCTGAGCGTACTGCATTCCTTTTGCAGCAGCTTCTTAATAAAGCGAACGCCGAGG GGGTTAAACTAACCAGCTCAATTAATACTCCCTACAGAAACACTATAAAACCTCACGAAGAAAAACAAATGCCTCCCGAT GAGGGAATTGGAAAGCGCATCAATGCATTAATTAGATGGAACGCTGTTGCAATGGTACTTAGGGCAGGTAAATACGCGCC AGAGCTTGGCGGCCACATCGCTTCTTATGCATCTGCATCAACGTTATATGAAACTGGATTTAACTATTTTTTTAAAGGAC AAAAAGGCGAAAATGGAGGAGACTTGCTTTATATTCAAGGCCACTCGGCTCCAGGCATTTATGCCAGAGCATTTCTTGAA GGCCGATTAACAGAGAAACAACTTGAAAAATTTCGGCAAGAAGTAGAGGTAGATGGTTTATCTTCCTACCCACACCCTTG GCTAATGAACGATTTTTGGCAATTTCCCACTGTATCCATGGGCTTAGGTCCTTTGCAAGCTATCTATCAAGCTCGCTTTC TAAAATATCTTGAGAACCGGGGACTGATCAAAGCTGAGGGTAGGAAAGTATGGGCATTTTTGGGTGATGGCGAGATGGAT GAGCCTGAATCAGTCGGGGCACTCAGTATCGCAGCACGAGAAAAGCTGGATAATCTCATTTTTGTAGTTAATTGCAATTT ACAAAGACTTGATGGGCCTGTTCGTGGTAACGGTAAAATCATTCAAGAACTTGAAGGCCTATTTCGAGGAGCTGGATGGA ACGTTATTAAGGTCATCTGGGGAGGCCGTTGGGATCCATTATTTGCCCGTGATAATCAAGGCTGGCTACAGAAAAGGATG GAAGAATGTCTGGATGGAGATTATCAATCTTACAAAGCGAACGATGGATCGTATGTAAGACAACATTTCTTTAATCAATA TCCAGAATTAAAGAAAATGGTTGAAAATATGTCTGATGAGGAAATTTGGCGATTAAATCGTGGTGGCCATGATCCTCAAA AAGTATATGCAGCTTATGCCAGAGCAGTTGAACACAAGGGAACTCCAACAGTTATCCTTGCAAAAACCATCAAGGGCTAC GGGATGGGAGCGGCTGGTGAGGGACAAAACATTACTCATCAGCAGAAAAAAATGACCATAGATCAACTAAAAGCTTTCAG AGATCGATTTAATATTCCAATCAGCGATGACAAAATTGCTGATATTCCTTTCTATAAACCCGATGACGACAGTCCCGAAA TCAAGTATATAAAAAAGCAAAGGGAAGCCTTGGGCGGTTATTTGCCCCACCGTTCAACTGAAGTAGAACAGTTAAAAATA CCTGATTTAGGAGAATTTTCCAGTATTACCAAGGGATTAGGAGATAGAGAAATCTCGACTACTATGGCATTTGTGCGAAT TCTTTCAGTTCTACTCAAAAATAAAGATATTAATTCCAGAATAGTCCCCATAGTACCAGATGAATGCAGAACATTCGGTA TGGAGGGATTATTCAGACAAATTGGAATTTATTCTCCCGTAGGTCAACTTTATACTCCTGTAGATCATGAGCAAGTGATG TATTACCGAGAAGCAGTTGACGGGCAGATTCTTGAAGAAGGTATTAATGAAGCTGGGGCGTTTTGTTCATGGATTGCTGC CGCAACCTCTTACAGTTCAAATAAGCTGGCAATGATTCCATTTTACATTTATTACTCTATGTTTGGTTTCCAACGCATTG GTGATTTAGCATGGGCGGCAGGAGATATGCAAGCGAGAGGATTTCTACTTGGTGGAACCGCTGGACGAACAACGTTGGCA GGAGAAGGATTGCAACACCAAGATGGACATAGTCATGTCTTAGCATCAACAATACCTAATTGTATTTCTTATGATCCCAC ATACGCCTATGAATTAGCAGTTATCATCCAAAATGGATTGCACCGTATGTATGAAAAACAGGAAAACGTGTTTTATTACA TTACTATTATGAATGAAAACTACTCTCATCCCGATATGCCTGCAGGAGTAGAGGAAGGTATTATCAAAGGAATGTATCTC TTAAAAGAAAATAAGAAAAAATCAAAAAACCATGTCCAACTAATGGGATGCGGTACTATTTTGCGTGAAGTTATCAAAGC CGCAGAGATGCTGGAAGAGGATTTTTCAATTACATCGGATATCTGGAGTGTAACTAGCTTCAATGAGTTACGTAAAGAAG GTTTGGCTGTAGAGCGATACAATAACATGCACCCCCAAAATAAGCCTCAGGAAAGTTATGTGACATCTCAATTAAAAGGA CGTCGTGGACCTGTTATTGCCTCAACTGACTATATGCGTATTTATGCAGATCAGATCAGGCCTTTTGTTCCTAATCGCTA TATTACCCTAGGTACAGACGGTTACGGCAGAAGTGATACCCGTACACAACTACGTCATTTCTTTGAAGTTGATGCAAAAT TTATAGTGTTGGCGGCATTAAATGCACTTGTAGCTGAAGGTAGTCTTGATAAAACAAAAATTGTCGATGCCATGAAACGT TACAATATTAATCAAGACAAATTGGATCCAATGACCCATTAG
Upstream 100 bases:
>100_bases TTGTAATTGCTCTGCGGATTTTAATGCATGTAATCAAGGTTGTTCTGGTGTAATTCAGAAAAGATTACAACCCGTACCAT ACTGTTCATAAAATTATTGA
Downstream 100 bases:
>100_bases TTAAACAATTAATCAGAACAGAAGATAGTTCCGGTTTAACTGAGTGCTGAGGAAAATATGACAAAAGAAAGTGAAATTAA AATTCCTGATATCGGTGGCG
Product: pyruvate dehydrogenase subunit E1
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 893; Mature: 893
Protein sequence:
>893_residues MLGNYFMTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSSINTPYRNTIKPHEEKQMPPD EGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASASTLYETGFNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLE GRLTEKQLEKFRQEVEVDGLSSYPHPWLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMD EPESVGALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIWGGRWDPLFARDNQGWLQKRM EECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDEEIWRLNRGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGY GMGAAGEGQNITHQQKKMTIDQLKAFRDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKI PDLGEFSSITKGLGDREISTTMAFVRILSVLLKNKDINSRIVPIVPDECRTFGMEGLFRQIGIYSPVGQLYTPVDHEQVM YYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIPFYIYYSMFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLA GEGLQHQDGHSHVLASTIPNCISYDPTYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYL LKENKKKSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERYNNMHPQNKPQESYVTSQLKG RRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDTRTQLRHFFEVDAKFIVLAALNALVAEGSLDKTKIVDAMKR YNINQDKLDPMTH
Sequences:
>Translated_893_residues MLGNYFMTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSSINTPYRNTIKPHEEKQMPPD EGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASASTLYETGFNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLE GRLTEKQLEKFRQEVEVDGLSSYPHPWLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMD EPESVGALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIWGGRWDPLFARDNQGWLQKRM EECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDEEIWRLNRGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGY GMGAAGEGQNITHQQKKMTIDQLKAFRDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKI PDLGEFSSITKGLGDREISTTMAFVRILSVLLKNKDINSRIVPIVPDECRTFGMEGLFRQIGIYSPVGQLYTPVDHEQVM YYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIPFYIYYSMFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLA GEGLQHQDGHSHVLASTIPNCISYDPTYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYL LKENKKKSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERYNNMHPQNKPQESYVTSQLKG RRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDTRTQLRHFFEVDAKFIVLAALNALVAEGSLDKTKIVDAMKR YNINQDKLDPMTH >Mature_893_residues MLGNYFMTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSSINTPYRNTIKPHEEKQMPPD EGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASASTLYETGFNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLE GRLTEKQLEKFRQEVEVDGLSSYPHPWLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMD EPESVGALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIWGGRWDPLFARDNQGWLQKRM EECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDEEIWRLNRGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGY GMGAAGEGQNITHQQKKMTIDQLKAFRDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKI PDLGEFSSITKGLGDREISTTMAFVRILSVLLKNKDINSRIVPIVPDECRTFGMEGLFRQIGIYSPVGQLYTPVDHEQVM YYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIPFYIYYSMFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLA GEGLQHQDGHSHVLASTIPNCISYDPTYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYL LKENKKKSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERYNNMHPQNKPQESYVTSQLKG RRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDTRTQLRHFFEVDAKFIVLAALNALVAEGSLDKTKIVDAMKR YNINQDKLDPMTH
Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge
COG id: COG2609
COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786304, Length=881, Percent_Identity=59.7048808172531, Blast_Score=1099, Evalue=0.0,
Paralogues:
None
Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004660 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005474 [H]
Pfam domain/function: PF00456 Transketolase_N [H]
EC number: =1.2.4.1 [H]
Molecular weight: Translated: 101103; Mature: 101103
Theoretical pI: Translated: 6.48; Mature: 6.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLGNYFMTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSS CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEC INTPYRNTIKPHEEKQMPPDEGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASAS CCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHH TLYETGFNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLEGRLTEKQLEKFRQEVEVDGL HHHHCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC SSYPHPWLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMD CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCC EPESVGALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIW CCCCCCHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEE GGRWDPLFARDNQGWLQKRMEECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDE CCCCCCCEECCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCHH EIWRLNRGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGYGMGAAGEGQNITHQQKKMTI HHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH DQLKAFRDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKI HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHEECC PDLGEFSSITKGLGDREISTTMAFVRILSVLLKNKDINSRIVPIVPDECRTFGMEGLFRQ CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHCHHHHHHH IGIYSPVGQLYTPVDHEQVMYYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIP HCCCCCHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHH FYIYYSMFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLAGEGLQHQDGHSHVLASTIPN HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEHHHHCCH CISYDPTYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYL HHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHH LKENKKKSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERY HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHH NNMHPQNKPQESYVTSQLKGRRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDT CCCCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHH RTQLRHFFEVDAKFIVLAALNALVAEGSLDKTKIVDAMKRYNINQDKLDPMTH HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHCCCCCCC >Mature Secondary Structure MLGNYFMTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSS CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEC INTPYRNTIKPHEEKQMPPDEGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASAS CCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHH TLYETGFNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLEGRLTEKQLEKFRQEVEVDGL HHHHCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC SSYPHPWLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMD CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCC EPESVGALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIW CCCCCCHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEE GGRWDPLFARDNQGWLQKRMEECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDE CCCCCCCEECCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCHH EIWRLNRGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGYGMGAAGEGQNITHQQKKMTI HHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH DQLKAFRDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKI HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHEECC PDLGEFSSITKGLGDREISTTMAFVRILSVLLKNKDINSRIVPIVPDECRTFGMEGLFRQ CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHCHHHHHHH IGIYSPVGQLYTPVDHEQVMYYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIP HCCCCCHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHH FYIYYSMFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLAGEGLQHQDGHSHVLASTIPN HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEHHHHCCH CISYDPTYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYL HHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHH LKENKKKSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERY HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHH NNMHPQNKPQESYVTSQLKGRRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDT CCCCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHH RTQLRHFFEVDAKFIVLAALNALVAEGSLDKTKIVDAMKRYNINQDKLDPMTH HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9171401; 10984043 [H]