Click here to switch to the map view.

The map label for this gene is bioD

Identifier: 52841705

GI number: 52841705

Start: 1628907

End: 1629545

Strand: Direct

Name: bioD

Synonym: lpg1475

Alternate gene names: 52841705

Gene position: 1628907-1629545 (Clockwise)

Preceding gene: 52841704

Following gene: 52841706

Centisome position: 47.94

GC content: 37.4

Gene sequence:

>639_bases
ATGAAACGATATTTTGTTACTGGTACTGACACTGATTGTGGTAAGACATTTGTAACCAATCAATTGGTTAATTATTTTTC
AGATTCAGCAGCGATAAAACCCATAGCAAGCGGATGTGAGTATAGTGAAAATCAATTAGTAAATTCTGATGCACTTTTAC
ACCAGCAACAGAATCATTTGCCTATGGAAATTGTTAATCCCTGGCGATTTAGATTGCCAGTTTCGCCGCACTTATCAGCA
AGGGAGGATGGTGCAAGTATTGATGTCCATAAAGTGGCTGATTATTGCCTTAATTTGCAAGTGAATGACATTAAGAAATT
ATTTATCGAAGGAGCCGGGGGATTAATGGTTCCTCTGAATGAGCAGGACACTTGGCTTGATTTTTTAAAATTAACCAGGA
TCCCTGTTATTTTAGTTGTAGGCATGAAGTTGGGTTGCATCAACCACACTTTGCTTAGCCAGGAAGTGCTCGAAATAAAT
AAAATCAAATGTCAAGGATGGATTGCTAATTGCCTGGATCAGGACATGCTAATGCTTGATGAAAATATTAGTACCCTTGA
AGCCAAATTAAACTATCCTTTATTAGCCAGGACAAACTATGGCGGCAAAATTTCTGATATATGTTTAAGCTCCTTGTAA

Upstream 100 bases:

>100_bases
ATTACCCGAATTTTAAGTATGTCCTCTTCAACAGAGCAGCTCACATGCCTTTTCTGTCCCATACCGATTTATTTATTACA
ATAATGGATGAATTTATAAA

Downstream 100 bases:

>100_bases
TCGCAGTGAAATTTTATATCAAAACAGCACTATATACCTGATCTTACTGCTTGTTCTGCTTGCGCTATACCCATGGCAGC
AATTATAATGAAAAGTTAAA

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSDSAAIKPIASGCEYSENQLVNSDALLHQQQNHLPMEIVNPWRFRLPVSPHLSA
REDGASIDVHKVADYCLNLQVNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLSQEVLEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLNYPLLARTNYGGKISDICLSSL

Sequences:

>Translated_212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSDSAAIKPIASGCEYSENQLVNSDALLHQQQNHLPMEIVNPWRFRLPVSPHLSA
REDGASIDVHKVADYCLNLQVNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLSQEVLEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLNYPLLARTNYGGKISDICLSSL
>Mature_212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSDSAAIKPIASGCEYSENQLVNSDALLHQQQNHLPMEIVNPWRFRLPVSPHLSA
REDGASIDVHKVADYCLNLQVNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLSQEVLEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLNYPLLARTNYGGKISDICLSSL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=204, Percent_Identity=37.7450980392157, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI87081944, Length=206, Percent_Identity=31.0679611650485, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324385, Length=156, Percent_Identity=31.4102564102564, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23758; Mature: 23758

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFVTGTDTDCGKTFVTNQLVNYFSDSAAIKPIASGCEYSENQLVNSDALLHQQQNHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEECCHHHHHHHCCCC
PMEIVNPWRFRLPVSPHLSAREDGASIDVHKVADYCLNLQVNDIKKLFIEGAGGLMVPLN
CCEECCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECC
EQDTWLDFLKLTRIPVILVVGMKLGCINHTLLSQEVLEINKIKCQGWIANCLDQDMLMLD
CCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHC
ENISTLEAKLNYPLLARTNYGGKISDICLSSL
CCCHHHHHCCCCCEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MKRYFVTGTDTDCGKTFVTNQLVNYFSDSAAIKPIASGCEYSENQLVNSDALLHQQQNHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEECCHHHHHHHCCCC
PMEIVNPWRFRLPVSPHLSAREDGASIDVHKVADYCLNLQVNDIKKLFIEGAGGLMVPLN
CCEECCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECC
EQDTWLDFLKLTRIPVILVVGMKLGCINHTLLSQEVLEINKIKCQGWIANCLDQDMLMLD
CCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHC
ENISTLEAKLNYPLLARTNYGGKISDICLSSL
CCCHHHHHCCCCCEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA