Click here to switch to the map view.

The map label for this gene is corC [H]

Identifier: 52841669

GI number: 52841669

Start: 1587973

End: 1588863

Strand: Reverse

Name: corC [H]

Synonym: lpg1439

Alternate gene names: 52841669

Gene position: 1588863-1587973 (Counterclockwise)

Preceding gene: 52841670

Following gene: 52841668

Centisome position: 46.76

GC content: 35.58

Gene sequence:

>891_bases
ATGCTAATCCATATGAAGTCGAGGAAAATGAACTTGAATAAATTGGAAGATGGTGGGTCGTGGTTTTCTCGTTTAAAACA
GTTCTTACAAGGAGAGCCACAAAATCAGGAAGAATTGGTCAGTTTATTAAGAGACGCGCAAATACGCTCCCTGATTAATT
CAGAGACCCTCGCAATGATTGAGGGAGCTATCCTTTTCTCAAAAATGCGTGTTCGAGACATAATGCTGCCTAAAAATCAA
ATGGTTTGCATTAATAAGGATGATGATTTTAAGCATATTATATCTATTGTAACTCAAACGGGACATTCACGTTTTCCTGT
AACGGGTGAAAATTCTGATGAAGTGGTTGGCATTTTGCACGCAAAAGATTTGTTAAAATATCAACCAGAAAATATGGAAT
CATTTGATTTATTGGACATCTGCCGCCAGGTAACTTTTGTACCTGAAAGCAGACGTCTTGATAGTCTGCTTAGTGAATTT
CGAAGTAATAGAAATCATATGGCTATTGTTGTTGATGAATATGGAGAGGTGTCAGGTTTCGTTACCATTGAAGATATCAT
TGAACAAATAATCGGTGACATAGAAGATGAATTTGATATCGATGAAGACGCCTATATTAAAACACATGAAGGACACTGCT
ATATCATCAAAGCCCATACTCCAATAGAAGAATTTAACGAACAGCTCAACGCTGATTTTAGTGACGAAACCTATGATACA
ATTGGTGGCATAGTATTAAATAAATTCGGCTATTTACCTCAACGAGGTGAAGTAATAATCATAGATGATTTTGAATTTAA
AGTTCTTAATGCCGATTCGAGAAGAATAAAGTTATTAGAATGTCTCGATAAAAGAAGTCCCGAGAAACTAAATTCTACTG
TTGAAGGATAA

Upstream 100 bases:

>100_bases
ATTCATGGAGTGTTGCATTTATTAGGGTATGATCATATAAAAGATGAAGAAGCCTCTATTATGCAAATGCTCGAAGCTAA
ATTACTAGCTGAATTAGGTT

Downstream 100 bases:

>100_bases
GTAATTCATGAGCAGCTCTATTCTCATTATTGATGATGACACAGAACTAACAGATTTATTAACCCAATATTTGGAACCAG
AAGGCTTTAATGTAGTATGT

Product: Mg2+ and Co2+ transporter CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MLIHMKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQ
MVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEF
RSNRNHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDT
IGGIVLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG

Sequences:

>Translated_296_residues
MLIHMKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQ
MVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEF
RSNRNHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDT
IGGIVLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
>Mature_296_residues
MLIHMKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQ
MVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEF
RSNRNHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDT
IGGIVLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=216, Percent_Identity=26.8518518518519, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI94681046, Length=200, Percent_Identity=33, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40068055, Length=196, Percent_Identity=31.6326530612245, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40068053, Length=196, Percent_Identity=31.6326530612245, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40068049, Length=150, Percent_Identity=32.6666666666667, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=47.6190476190476, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI87082033, Length=265, Percent_Identity=27.5471698113208, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693175, Length=245, Percent_Identity=25.7142857142857, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788119, Length=229, Percent_Identity=27.0742358078603, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790664, Length=222, Percent_Identity=25.2252252252252, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34062; Mature: 34062

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIHMKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMI
CEEEECCCCCCCHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
EGAILFSKMRVRDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILH
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHH
AKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGF
HHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
VTIEDIIEQIIGDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDT
EEHHHHHHHHHHCCHHHCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHCCCCCCCHHHH
IGGIVLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
HHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MLIHMKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMI
CEEEECCCCCCCHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
EGAILFSKMRVRDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILH
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHH
AKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGF
HHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
VTIEDIIEQIIGDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDT
EEHHHHHHHHHHCCHHHCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHCCCCCCCHHHH
IGGIVLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
HHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]