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The map label for this gene is cdd

Identifier: 52841665

GI number: 52841665

Start: 1584510

End: 1584905

Strand: Reverse

Name: cdd

Synonym: lpg1435

Alternate gene names: 52841665

Gene position: 1584905-1584510 (Counterclockwise)

Preceding gene: 52841666

Following gene: 52841664

Centisome position: 46.65

GC content: 35.35

Gene sequence:

>396_bases
ATGGATAAATTAACTTCGAACATGATTAATGAAGCGCATAAGGTGCTAGTCAACGCTTATGCCCCCTATTCCAAATTTTC
AGTAGCTGCCTGTATATGCACTGATAAAAATAATTTTTATACAGGGGTCAATGTAGAAAATATTTCTTATGGGCTAACAA
CCTGTGCTGAAGTTTCAGCGATTTGTAATATGGTTACCGCAGGTGAGCGAAAAATTAAAAGCATTGTGGTATTAGCTGCA
AACAATTTGCTATGTTCTCCTTGTGGTGCATGCCGACAAAGAATTCATGAGTTTTCATCCTCTGATACCATGGTACATCT
CTGTAATAAAGAAACAATATTTCATAGTATTACCATTAATGAATTACTACCCTTGGCTTTTGATTTTAACCCTTAA

Upstream 100 bases:

>100_bases
AAGAACCGTCTCCAGATCTTCAAATGGATTTATCCTCTCGTACTTGTAAACCACAGTATTAATTTAGTATATTCTGCACG
CCAATGATGAGGGTGTGACA

Downstream 100 bases:

>100_bases
TCGGACGACTTTATGACGACTTCAATATCCACTATCAGTTACCCACATTTAGCAGCAGAATATATTCAAAAAACATGTCC
ATCATTTAAACCAAAAGTGG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MDKLTSNMINEAHKVLVNAYAPYSKFSVAACICTDKNNFYTGVNVENISYGLTTCAEVSAICNMVTAGERKIKSIVVLAA
NNLLCSPCGACRQRIHEFSSSDTMVHLCNKETIFHSITINELLPLAFDFNP

Sequences:

>Translated_131_residues
MDKLTSNMINEAHKVLVNAYAPYSKFSVAACICTDKNNFYTGVNVENISYGLTTCAEVSAICNMVTAGERKIKSIVVLAA
NNLLCSPCGACRQRIHEFSSSDTMVHLCNKETIFHSITINELLPLAFDFNP
>Mature_131_residues
MDKLTSNMINEAHKVLVNAYAPYSKFSVAACICTDKNNFYTGVNVENISYGLTTCAEVSAICNMVTAGERKIKSIVVLAA
NNLLCSPCGACRQRIHEFSSSDTMVHLCNKETIFHSITINELLPLAFDFNP

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=119, Percent_Identity=36.1344537815126, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17551074, Length=127, Percent_Identity=39.3700787401575, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=121, Percent_Identity=38.8429752066116, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=129, Percent_Identity=38.7596899224806, Blast_Score=77, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19920920, Length=111, Percent_Identity=34.2342342342342, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24582741, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582744, Length=90, Percent_Identity=37.7777777777778, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14386; Mature: 14386

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLTSNMINEAHKVLVNAYAPYSKFSVAACICTDKNNFYTGVNVENISYGLTTCAEVSA
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEECCEECCCCCCHHHHHHHHH
ICNMVTAGERKIKSIVVLAANNLLCSPCGACRQRIHEFSSSDTMVHLCNKETIFHSITIN
HHHHHHCCCHHHHEEEEEECCCCEECCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEHH
ELLPLAFDFNP
HHCCEEECCCC
>Mature Secondary Structure
MDKLTSNMINEAHKVLVNAYAPYSKFSVAACICTDKNNFYTGVNVENISYGLTTCAEVSA
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEECCEECCCCCCHHHHHHHHH
ICNMVTAGERKIKSIVVLAANNLLCSPCGACRQRIHEFSSSDTMVHLCNKETIFHSITIN
HHHHHHCCCHHHHEEEEEECCCCEECCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEHH
ELLPLAFDFNP
HHCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]