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The map label for this gene is glpD

Identifier: 52841643

GI number: 52841643

Start: 1558192

End: 1559712

Strand: Reverse

Name: glpD

Synonym: lpg1413

Alternate gene names: 52841643

Gene position: 1559712-1558192 (Counterclockwise)

Preceding gene: 52841645

Following gene: 52841639

Centisome position: 45.9

GC content: 39.25

Gene sequence:

>1521_bases
ATGGATCAGGTTTTTGATGTTGCAATTATTGGTGGAGGCATCAATGGCTGCGGCTGCGCTGCAGATGCAGCATTAAGAGG
TCTGTCTGTGATACTCTTCGAACAGGACGATCTGGCTTCGAAAACATCATCAAGTAGCACAAAATTAATTCATGGTGGTT
TAAGGTATTTAGAGCATTATGAGTTTGGTTTAGTCAAAAAAGCACTCCAGGAACGTCAAACGCTTCTCAATTTGGCTCCC
CATTTAGTCCATTCCCAATCTTTTGTTTTGCCCTACTTAAAACATATGCGCCCCTCATGGTTATTGAGGTTAGGCTTATT
TTTTTACGATCATCTCAGTCGAAAAAATCATTTACCCAAATCCAGATCGATCCACAGAAATAATAAGAATAATTATTTTA
CGCCACTAAAAGAGGAGCTAAATCGCGGTTTTCTTTTCTATGATGCCACCACCGATGATGCTCGCTTAACCATTCTTAAT
GCCATACAAGCCAAAAATCATGGCGCAAGCATAAGGCCACATGCCAAAGTAACCCATGCAGAGGTAATCAATAACATATG
GCATTTAACTATCCAGCCCACCAAAGGGCAGAGCTATAAAGCTTATGCTAAAAGCATCATTAATGCCACAGGACCATGGG
TGCAATCCATTGCCCAATTAACTCATACACCTATCCAAAAAGATATTACCCTGGTTAAAGGTAGCCATATTATCGTCCCC
AAACTTTTTGAGGGAAATCATGCCTATTTCTTGCAACATAATGATCAGCGGGTTATTTTTGTTATCCCCTATCATGGCTT
TAGTATGATTGGAACCACCGATATCCACTATACTGGGGATCTTAACCACATAGAGATTGGCGAAGAAGAAATTGATTACT
TAATTGAATTGGTAAATGCCTACTTCAAGTTTAAAATAACTAAAGAAGATGTAGTCCATTCCTGGAGCGGCATAAGGCCT
TTGTTAGCTGATGATAGCAAAGAAGTCAAATCATTAAGTCGTGACTATTCCTATGAGTTTAACCACTCCCCAGCTCCCAT
TATTACAATTTTTGGAGGGAAAATAACCACTTATAGACAGTTGGCTGAAGAAGTTGTAGATCAACTTACCCCTGTATTTC
CACAAATGAAGCCATCGAAAACACAACATACGCCCTTACCTGGGGCAACTTTAGCAGATATGAGTTTTACTCAATATGTC
AATTACGCCAAAACAAAATATCATTGGCTGGATGATGAACTATTAAATCGCTACCTCAATACCTATGGTTGTTATACTGA
AATTTTTCTTTCGCAATGCAACAATATGGAAGCAATGGGGAAAAAATATGGCCCATCACTCTACCAGGTGGAAGTAGATT
ATCTTATTTTAGAAGAGTGGGCGAATTATTGTGATGACATACTTAACCGCCGCACTAAACTCGGCCTTACTATGGATAAT
GCCAGTAAAAAAGAACTTGCGGATTATCTGGCTAGTATATCTACTTATCCTTCTGCTCAAGCTGAGCTCGTATTTCACTA
A

Upstream 100 bases:

>100_bases
ACTACTTGTTCCCTGGTCAATAGCTAGTATATAGTTCATTATTGTAAAATCCCTCTATATTTATAGATATTGAGTGTAAT
CTTTTTTCGGAGATAAAAAC

Downstream 100 bases:

>100_bases
CATCAGCATCAAGTGCTTGTTGCGCCAATTCTTTTAAAGTGGACTCGGGTATGCTTCCAGCATCAGAATAAATAACAATA
CTGTCTTTGAAAACCATAAG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDQVFDVAIIGGGINGCGCAADAALRGLSVILFEQDDLASKTSSSSTKLIHGGLRYLEHYEFGLVKKALQERQTLLNLAP
HLVHSQSFVLPYLKHMRPSWLLRLGLFFYDHLSRKNHLPKSRSIHRNNKNNYFTPLKEELNRGFLFYDATTDDARLTILN
AIQAKNHGASIRPHAKVTHAEVINNIWHLTIQPTKGQSYKAYAKSIINATGPWVQSIAQLTHTPIQKDITLVKGSHIIVP
KLFEGNHAYFLQHNDQRVIFVIPYHGFSMIGTTDIHYTGDLNHIEIGEEEIDYLIELVNAYFKFKITKEDVVHSWSGIRP
LLADDSKEVKSLSRDYSYEFNHSPAPIITIFGGKITTYRQLAEEVVDQLTPVFPQMKPSKTQHTPLPGATLADMSFTQYV
NYAKTKYHWLDDELLNRYLNTYGCYTEIFLSQCNNMEAMGKKYGPSLYQVEVDYLILEEWANYCDDILNRRTKLGLTMDN
ASKKELADYLASISTYPSAQAELVFH

Sequences:

>Translated_506_residues
MDQVFDVAIIGGGINGCGCAADAALRGLSVILFEQDDLASKTSSSSTKLIHGGLRYLEHYEFGLVKKALQERQTLLNLAP
HLVHSQSFVLPYLKHMRPSWLLRLGLFFYDHLSRKNHLPKSRSIHRNNKNNYFTPLKEELNRGFLFYDATTDDARLTILN
AIQAKNHGASIRPHAKVTHAEVINNIWHLTIQPTKGQSYKAYAKSIINATGPWVQSIAQLTHTPIQKDITLVKGSHIIVP
KLFEGNHAYFLQHNDQRVIFVIPYHGFSMIGTTDIHYTGDLNHIEIGEEEIDYLIELVNAYFKFKITKEDVVHSWSGIRP
LLADDSKEVKSLSRDYSYEFNHSPAPIITIFGGKITTYRQLAEEVVDQLTPVFPQMKPSKTQHTPLPGATLADMSFTQYV
NYAKTKYHWLDDELLNRYLNTYGCYTEIFLSQCNNMEAMGKKYGPSLYQVEVDYLILEEWANYCDDILNRRTKLGLTMDN
ASKKELADYLASISTYPSAQAELVFH
>Mature_506_residues
MDQVFDVAIIGGGINGCGCAADAALRGLSVILFEQDDLASKTSSSSTKLIHGGLRYLEHYEFGLVKKALQERQTLLNLAP
HLVHSQSFVLPYLKHMRPSWLLRLGLFFYDHLSRKNHLPKSRSIHRNNKNNYFTPLKEELNRGFLFYDATTDDARLTILN
AIQAKNHGASIRPHAKVTHAEVINNIWHLTIQPTKGQSYKAYAKSIINATGPWVQSIAQLTHTPIQKDITLVKGSHIIVP
KLFEGNHAYFLQHNDQRVIFVIPYHGFSMIGTTDIHYTGDLNHIEIGEEEIDYLIELVNAYFKFKITKEDVVHSWSGIRP
LLADDSKEVKSLSRDYSYEFNHSPAPIITIFGGKITTYRQLAEEVVDQLTPVFPQMKPSKTQHTPLPGATLADMSFTQYV
NYAKTKYHWLDDELLNRYLNTYGCYTEIFLSQCNNMEAMGKKYGPSLYQVEVDYLILEEWANYCDDILNRRTKLGLTMDN
ASKKELADYLASISTYPSAQAELVFH

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=522, Percent_Identity=31.992337164751, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI285002231, Length=522, Percent_Identity=31.992337164751, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=39.7435897435897, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788574, Length=386, Percent_Identity=27.720207253886, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115534726, Length=529, Percent_Identity=30.812854442344, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17509253, Length=515, Percent_Identity=32.4271844660194, Blast_Score=191, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6322036, Length=467, Percent_Identity=31.9057815845824, Blast_Score=180, Evalue=5e-46,
Organism=Drosophila melanogaster, GI161077125, Length=407, Percent_Identity=34.3980343980344, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653942, Length=407, Percent_Identity=34.3980343980344, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653944, Length=407, Percent_Identity=34.3980343980344, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI20130025, Length=407, Percent_Identity=34.3980343980344, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24586295, Length=390, Percent_Identity=30.5128205128205, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19921278, Length=496, Percent_Identity=24.7983870967742, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45550977, Length=368, Percent_Identity=21.7391304347826, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57639; Mature: 57639

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3 ; PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQVFDVAIIGGGINGCGCAADAALRGLSVILFEQDDLASKTSSSSTKLIHGGLRYLEHY
CCCEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
EFGLVKKALQERQTLLNLAPHLVHSQSFVLPYLKHMRPSWLLRLGLFFYDHLSRKNHLPK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
SRSIHRNNKNNYFTPLKEELNRGFLFYDATTDDARLTILNAIQAKNHGASIRPHAKVTHA
CCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCEEHHHHHHHCCCCCCCCCCCCHHHH
EVINNIWHLTIQPTKGQSYKAYAKSIINATGPWVQSIAQLTHTPIQKDITLVKGSHIIVP
HHHCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCEEEECCCEEEEE
KLFEGNHAYFLQHNDQRVIFVIPYHGFSMIGTTDIHYTGDLNHIEIGEEEIDYLIELVNA
EEECCCEEEEEEECCCEEEEEECCCCCEEEECCEEEECCCCCEEECCHHHHHHHHHHHHH
YFKFKITKEDVVHSWSGIRPLLADDSKEVKSLSRDYSYEFNHSPAPIITIFGGKITTYRQ
HHEEEECHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHH
LAEEVVDQLTPVFPQMKPSKTQHTPLPGATLADMSFTQYVNYAKTKYHWLDDELLNRYLN
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHH
TYGCYTEIFLSQCNNMEAMGKKYGPSLYQVEVDYLILEEWANYCDDILNRRTKLGLTMDN
HHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHCCEEECC
ASKKELADYLASISTYPSAQAELVFH
CCHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MDQVFDVAIIGGGINGCGCAADAALRGLSVILFEQDDLASKTSSSSTKLIHGGLRYLEHY
CCCEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
EFGLVKKALQERQTLLNLAPHLVHSQSFVLPYLKHMRPSWLLRLGLFFYDHLSRKNHLPK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
SRSIHRNNKNNYFTPLKEELNRGFLFYDATTDDARLTILNAIQAKNHGASIRPHAKVTHA
CCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCEEHHHHHHHCCCCCCCCCCCCHHHH
EVINNIWHLTIQPTKGQSYKAYAKSIINATGPWVQSIAQLTHTPIQKDITLVKGSHIIVP
HHHCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCEEEECCCEEEEE
KLFEGNHAYFLQHNDQRVIFVIPYHGFSMIGTTDIHYTGDLNHIEIGEEEIDYLIELVNA
EEECCCEEEEEEECCCEEEEEECCCCCEEEECCEEEECCCCCEEECCHHHHHHHHHHHHH
YFKFKITKEDVVHSWSGIRPLLADDSKEVKSLSRDYSYEFNHSPAPIITIFGGKITTYRQ
HHEEEECHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHH
LAEEVVDQLTPVFPQMKPSKTQHTPLPGATLADMSFTQYVNYAKTKYHWLDDELLNRYLN
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHH
TYGCYTEIFLSQCNNMEAMGKKYGPSLYQVEVDYLILEEWANYCDDILNRRTKLGLTMDN
HHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHCCEEECC
ASKKELADYLASISTYPSAQAELVFH
CCHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]