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The map label for this gene is erpA [H]

Identifier: 52841618

GI number: 52841618

Start: 1535420

End: 1535812

Strand: Reverse

Name: erpA [H]

Synonym: lpg1388

Alternate gene names: 52841618

Gene position: 1535812-1535420 (Counterclockwise)

Preceding gene: 52841619

Following gene: 52841615

Centisome position: 45.2

GC content: 35.11

Gene sequence:

>393_bases
ATGGCCAATCTTGACGTATCACAAAATACTTCAGATATACATTTTTCTGTCAGTGCAGCAGATAAAGTCGCAGAACTAAT
CAAAGAAGAAGATAATTCCAATTTGAATTTACGAGTTTCAATTACAGGCGGTGGTTGTTCTGGATTTCAATACGGATTTA
GCTTTGATGAACAAATCAATGATGACGACACTATTGTGATACAACAATGTTCTGATGGAAAATCCTCTGTCAAATTGCTA
GTTGACTCAATGAGTTATCAATATTTGCATGATGCGGAAATCGATTACATTAAAGGAATACAAGGAGAGCAATTTGTCAT
ACGCAACCCTAATGCAAAAACAACTTGTGGTTGTGGCTCTTCGTTTAGTATTGGTGATGAAGATGATTTATAA

Upstream 100 bases:

>100_bases
TTCTCTGGTCCCTAATACCAATTTATGGATTGAGACTACGAAACAACTTGTATTATTGATATAATGAATTGTAGAGGTAG
TAATTATTTTGGAGCTTAGT

Downstream 100 bases:

>100_bases
AAAAATCACTGCCTGAAACTCAAGGCAGTGATCTTAGCTTTTTACGGACGAACTGCTTATTATTCTTAAGCACCTCGGGT
AGGAGCAGGAGATCGAAGAT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MANLDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQINDDDTIVIQQCSDGKSSVKLL
VDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL

Sequences:

>Translated_130_residues
MANLDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQINDDDTIVIQQCSDGKSSVKLL
VDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL
>Mature_129_residues
ANLDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQINDDDTIVIQQCSDGKSSVKLLV
DSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=89, Percent_Identity=42.6966292134831, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI52426768, Length=112, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786351, Length=112, Percent_Identity=56.25, Blast_Score=135, Evalue=6e-34,
Organism=Escherichia coli, GI1788877, Length=112, Percent_Identity=33.9285714285714, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=32.4074074074074, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=123, Percent_Identity=30.8943089430894, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325324, Length=135, Percent_Identity=30.3703703703704, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323001, Length=88, Percent_Identity=37.5, Blast_Score=60, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24649697, Length=119, Percent_Identity=34.453781512605, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 14146; Mature: 14014

Theoretical pI: Translated: 3.91; Mature: 3.91

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQIN
CCCCCCCCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
DDDTIVIQQCSDGKSSVKLLVDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGS
CCCEEEEEECCCCCCCEEEEEECCCCEEECCCCCCEECCCCCCEEEEECCCCCEEECCCC
SFSIGDEDDL
CCCCCCCCCC
>Mature Secondary Structure 
ANLDVSQNTSDIHFSVSAADKVAELIKEEDNSNLNLRVSITGGGCSGFQYGFSFDEQIN
CCCCCCCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
DDDTIVIQQCSDGKSSVKLLVDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGS
CCCEEEEEECCCCCCCEEEEEECCCCEEECCCCCCEECCCCCCEEEEECCCCCEEECCCC
SFSIGDEDDL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA