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The map label for this gene is rodA

Identifier: 52841604

GI number: 52841604

Start: 1520302

End: 1521420

Strand: Reverse

Name: rodA

Synonym: lpg1374

Alternate gene names: 52841604

Gene position: 1521420-1520302 (Counterclockwise)

Preceding gene: 52841605

Following gene: 52841602

Centisome position: 44.78

GC content: 41.29

Gene sequence:

>1119_bases
ATGAGTAGACAAACGACTAAGCCCGTATATCGTTTTACAGCAAAGTCCCTTCATCTTGATTTTCCATTACTTGGATTAAT
ACTTACTCTTATTGCCTTCGGACTCTTGATACTTTATAGCGCTTCAAATGCCAATATGGGCATGATCATGCGCCAATCCA
TGAGGCTGCTCTTCGCTTTTCTAATCATGTTTGTACTTGGATTTATTCCGCCACATAAATATAAAATCTGGACCCCATGG
ATTTACGGGGTTGGGTTAAGCTTGTTAATCGCAGTCATGCTAATGGGTAAAATTGGTAAAGGGGCTCAGCGCTGGTTAGA
ACTGGGGTTATTTCGTTTTCAACCTTCCGAGATTATGAAACTGGCTGTACCTATGATGGCCGCCTGGTTTTTCGACCGAC
AATCTCATCCAAGCAGCATACGCTCAATTGGTATTGCTTCCCTGATTATTTTTATTCCGGCTCTTCTTATTGCAAAACAA
CCTGATCTAGGTACTGCAATTATGGTTACTGTTGCAGGTTTATGTGTCGTATTTTTGGCAGGAATACGTTTTAAAATCAT
ATTATTAATTGCATTACTGATGTGCTCAGCAATTCCTGTTGTGTGGAATCTGATGCATGACTACCAGAAACAAAGAGTGT
ATACCCTGATTGATCCTGAACAAGATCCACTTGGTGCTGGCTATCACATTATTCAATCCAAAATTGCCATTGGCTCAGGC
GGCCTAATGGGCAAAGGATGGTTAAAGGGTAGTCAATCACACCTCAATTTCTTGCCAGAACATGCTACTGATTTTATTTT
TGCGGTAAGTGGCGAAGAATTTGGCTTTGCCGGCGGATTTGCTATTGTCGCGCTGATAGTCTTAATTTCGCTACGCAGTT
TAAATATTGCCAATAATGCACAAACCACTTACACGCGCCTGCTTTCAGCCAGTCTGGCCATGACCTTTTTCCTTTCTGCA
TTTGTCAATATTGGTATGGTCATGGGGATTATTCCGGTTGTAGGTATACCTCTTCCACTCGTCAGTTATGGTGGAACAGC
TATGGTAACTTTCCTGGCAAGCTTTGGAATTTTAATGTCGATAAGCTCGCACCGAATATTATTTAATAGCTTGAATTGA

Upstream 100 bases:

>100_bases
TTGCCATTGCGGTGGTAGTTGAAAATGATACTATCGCTTCCACTGTAGCACGTAAGGTACTTGACACTTATTATCAACTT
TATCCTATTAAGAAAACACC

Downstream 100 bases:

>100_bases
TTTATTTTTTTATGCTCTGATTTGCATAAATCATATTATGACATTTTAAAAGCTATTTCTTATGTATTTTTATTTGAACG
GTATTTTCCAAATTAATACC

Product: rod shape determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSRQTTKPVYRFTAKSLHLDFPLLGLILTLIAFGLLILYSASNANMGMIMRQSMRLLFAFLIMFVLGFIPPHKYKIWTPW
IYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMKLAVPMMAAWFFDRQSHPSSIRSIGIASLIIFIPALLIAKQ
PDLGTAIMVTVAGLCVVFLAGIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNAQTTYTRLLSASLAMTFFLSA
FVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMSISSHRILFNSLN

Sequences:

>Translated_372_residues
MSRQTTKPVYRFTAKSLHLDFPLLGLILTLIAFGLLILYSASNANMGMIMRQSMRLLFAFLIMFVLGFIPPHKYKIWTPW
IYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMKLAVPMMAAWFFDRQSHPSSIRSIGIASLIIFIPALLIAKQ
PDLGTAIMVTVAGLCVVFLAGIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNAQTTYTRLLSASLAMTFFLSA
FVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMSISSHRILFNSLN
>Mature_371_residues
SRQTTKPVYRFTAKSLHLDFPLLGLILTLIAFGLLILYSASNANMGMIMRQSMRLLFAFLIMFVLGFIPPHKYKIWTPWI
YGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMKLAVPMMAAWFFDRQSHPSSIRSIGIASLIIFIPALLIAKQP
DLGTAIMVTVAGLCVVFLAGIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSGG
LMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNAQTTYTRLLSASLAMTFFLSAF
VNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMSISSHRILFNSLN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=367, Percent_Identity=51.4986376021798, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1786277, Length=359, Percent_Identity=30.9192200557103, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40826; Mature: 40695

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQTTKPVYRFTAKSLHLDFPLLGLILTLIAFGLLILYSASNANMGMIMRQSMRLLFAF
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LIMFVLGFIPPHKYKIWTPWIYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMK
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LAVPMMAAWFFDRQSHPSSIRSIGIASLIIFIPALLIAKQPDLGTAIMVTVAGLCVVFLA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNA
CCCCCCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
QTTYTRLLSASLAMTFFLSAFVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
ISSHRILFNSLN
CCCCEEEEECCC
>Mature Secondary Structure 
SRQTTKPVYRFTAKSLHLDFPLLGLILTLIAFGLLILYSASNANMGMIMRQSMRLLFAF
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LIMFVLGFIPPHKYKIWTPWIYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMK
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LAVPMMAAWFFDRQSHPSSIRSIGIASLIIFIPALLIAKQPDLGTAIMVTVAGLCVVFLA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNA
CCCCCCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
QTTYTRLLSASLAMTFFLSAFVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
ISSHRILFNSLN
CCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]