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The map label for this gene is ruvA

Identifier: 52841519

GI number: 52841519

Start: 1415804

End: 1416403

Strand: Direct

Name: ruvA

Synonym: lpg1288

Alternate gene names: 52841519

Gene position: 1415804-1416403 (Clockwise)

Preceding gene: 52841518

Following gene: 52841520

Centisome position: 41.67

GC content: 39.33

Gene sequence:

>600_bases
ATGATAGGCTGGCTCCATGGTCAAATTATAGATAAGCATCAGCCAGGAAAATTGGTTCTTGATGTCAATGGCGTAGGATA
TGATGTAGAAACATCTTTGAATACTTTTTTTCAGATAGAAAATGGTAACCAACCTGTCGGATTACATATTCACACCATAG
TTCGAGAAGATGCTTTGTTATTGTATGGCTTCCTGGATAAAGAGGAGCGTTCTTTATTCAGATCATTAATTAAAGTGAAT
GGGGTAGGCCCCAAACTGGCTATGACTGTTTTATCCAGTATTTCTCCTAAGGAATTTATTCAGTGTATTCACCAGGAGAA
TGCTGCTTTATTAACCAAATTACCTGGCATAGGCAAGAAAACTGCAGAGCGCTTAGTAGTTGAAATGAGAGACAGTATAA
AACAATTTGATGGTTCGGTTTCCGATACCTTCCAAAAGCAGGCAGGTAGCACTCATAGTCAACAAGAGGCAATCAGCGCG
TTGGAGGCATTAGGCTATAAGCCACAAGAGGCGTGGAAAGTTATGAATAAAATTGATAATGGCAATAAGAGTTGTGAGCA
ATTGATTCGTGAGGCTTTGCAAATTCTTTCTTCGCGATGA

Upstream 100 bases:

>100_bases
CTGCCGATGCTTTGGCAATAGCAATATGTCATAGCCATATGAGAAATGGTTTGTCAAAATTAATCGGTTCAAGAGGAACG
AAACGCAGGAGGATGAGACT

Downstream 100 bases:

>100_bases
GATTGTAACTGTGATCTGATAAAATTCTCGATAATAAACAGGAGCATTTATGAAAAGAATGATCGGTTTTATGGTAAGTG
TGATGCTAACCTTTGCTGTC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPVGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVN
GVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISA
LEALGYKPQEAWKVMNKIDNGNKSCEQLIREALQILSSR

Sequences:

>Translated_199_residues
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPVGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVN
GVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISA
LEALGYKPQEAWKVMNKIDNGNKSCEQLIREALQILSSR
>Mature_199_residues
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPVGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVN
GVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISA
LEALGYKPQEAWKVMNKIDNGNKSCEQLIREALQILSSR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=47.5490196078431, Blast_Score=187, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22126; Mature: 22126

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPVGLHIHTIVREDALL
CCCCCCCCEECCCCCCEEEEEECCCCEEHCCCCCEEEEECCCCCCEEEEEHHHHHHCHHH
LYGFLDKEERSLFRSLIKVNGVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKK
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCHH
TAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISALEALGYKPQEAWKVMNKIDN
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GNKSCEQLIREALQILSSR
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPVGLHIHTIVREDALL
CCCCCCCCEECCCCCCEEEEEECCCCEEHCCCCCEEEEECCCCCCEEEEEHHHHHHCHHH
LYGFLDKEERSLFRSLIKVNGVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKK
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCHH
TAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISALEALGYKPQEAWKVMNKIDN
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GNKSCEQLIREALQILSSR
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA