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The map label for this gene is ruvC

Identifier: 52841518

GI number: 52841518

Start: 1415283

End: 1415807

Strand: Direct

Name: ruvC

Synonym: lpg1287

Alternate gene names: 52841518

Gene position: 1415283-1415807 (Clockwise)

Preceding gene: 52841517

Following gene: 52841519

Centisome position: 41.65

GC content: 40.95

Gene sequence:

>525_bases
ATGACGATTATATTAGGGATAGATCCAGGCTCACGGGTTACAGGATATGGATTGATTAAAGAATCTGACCGTAAAATTGC
GTACATCGATAGCGGCTGTATTCGCACATCAAACGATACGGAATTAAGTCATAAATTATTGCAAATATATGATGGAATAT
GTGAGCTAATGGATCACTATTCCCCAACTGAGGTTGCTATTGAGCAGATATTTATGCATAACAATCCTAATTCAGCTTTG
AAATTAGGACATGCGCGGGGGGTTGCCATGGTAGCAGCAGCCTCACATCGTGCGAAAATCTTTGAGTATTCAGCAAGAGA
AATAAAGCAAAGTGTAGTTGGTTATGGGGCCGCTGAAAAAGATCAAGTGAGTCATATGGTTGTAGAGCTTCTTCAGCTCA
ATCGAGCTCCTCAAAAAGACGCTGCCGATGCTTTGGCAATAGCAATATGTCATAGCCATATGAGAAATGGTTTGTCAAAA
TTAATCGGTTCAAGAGGAACGAAACGCAGGAGGATGAGACTATGA

Upstream 100 bases:

>100_bases
GTTTAATTAAACTGATTGACATGCTGGAGGATTTGGATGACGTACAAGAAGTTTACAGCAATGCTGAATTCTCTGAAAAA
ATATTAGAATCAATGAATTA

Downstream 100 bases:

>100_bases
TAGGCTGGCTCCATGGTCAAATTATAGATAAGCATCAGCCAGGAAAATTGGTTCTTGATGTCAATGGCGTAGGATATGAT
GTAGAAACATCTTTGAATAC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDTELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSAL
KLGHARGVAMVAAASHRAKIFEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSK
LIGSRGTKRRRMRL

Sequences:

>Translated_174_residues
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDTELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSAL
KLGHARGVAMVAAASHRAKIFEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSK
LIGSRGTKRRRMRL
>Mature_173_residues
TIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDTELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSALK
LGHARGVAMVAAASHRAKIFEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKL
IGSRGTKRRRMRL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=174, Percent_Identity=54.5977011494253, Blast_Score=167, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 19215; Mature: 19084

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDTELSHKLLQIYDGICELMDHY
CEEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHCC
SPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKIFEYSAREIKQSVVGYGAAEK
CHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
TIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDTELSHKLLQIYDGICELMDHY
EEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHCC
SPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKIFEYSAREIKQSVVGYGAAEK
CHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA