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The map label for this gene is yusZ [H]

Identifier: 52841377

GI number: 52841377

Start: 1257597

End: 1258481

Strand: Reverse

Name: yusZ [H]

Synonym: lpg1143

Alternate gene names: 52841377

Gene position: 1258481-1257597 (Counterclockwise)

Preceding gene: 52841378

Following gene: 52841376

Centisome position: 37.04

GC content: 37.85

Gene sequence:

>885_bases
ATGACGAAGACGGATAAAAAAATAGTGGTGGTCACAGGTTGTTCAAAAACATCTGGCGTAGGATATAATCTTGTATGTGA
AATGCTAAAGCGCGGGCATCAAGTCATTGCAACGGTGAGAAATCTTGAAACAAGCCAAATTAACAAAGCAAACCTCCCAA
ACTCCAGCAATTTGGATGTAAAAATATTGGATCTTTGCGATGAAAATTCAATTGACCGCTTTATTAAAGAAGTCTTAAGT
CAATATCAATACATTGACGCCTTGGTTAACAATGCTGCTAATGTGGCTATTGGCCCTGTTGAAAGCGCAACCACTCAAGA
TGTATTAACAACTTTTCAAACCAAAGTATTTGGCCCATTGTCTTTAATCAGGGGATTCATCCCTGTAATGAGAGAAAGGA
AAAAAGGTTTATTAACAACAACATCGACGATTTTTACCTCTGTTCCCGTTAGTATTCCAGGTGTCGCAATCTATTTTTCA
GCACTCGCAGCATTTGAACGATTACAAGAATCCTTGGCGATTGAGCTGGCCCCATGGAATATCAAAGTAATTAATTTCCA
ACCTGGGCCAATTACCACAGAATTGACCCGATTTGATGGCTCTCGCGCTGATATTGTTGAGAAATACTATAAAAACTTTA
CTGAACAAGCTTATCAATGGTTCCATCAGAATACTGTTTTTCAAAATGCAGCGGAAGTAGCCAAGGTATTTGCTGAAGTT
ATTGATATGGAGAATCCTGATTTATGCTATCAAAGCAATCTTTTTGGAAAGCAGTTTGTTGCAAAAAACAAAAAAGATAC
AACAGGGCGTGAAGGAATGGACAAGCTTCTGGAGCATTTCAAAAATTTACCCCATGACAATCCTGATGATTGGAAAATTC
AATAA

Upstream 100 bases:

>100_bases
AAAACCTTTTTAACAAAGAGATTGGGGTTTTTCGTAAGTTCTGAATAAATAAAAGGGCTATACTCGGTTTATTACTCTAA
AAGATCATTAGGATAGGGAC

Downstream 100 bases:

>100_bases
ATGATTTACTGGATAAAGTCATACTATCCGCCGCGAAATCTTTGTGCATAAGCAAAAAATCGATCATGCCCGCGCAGGCG
GGCAACCATTCCTCGCTTAC

Product: short chain type dehydrogenase/reductase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLPNSSNLDVKILDLCDENSIDRFIKEVLS
QYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPLSLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFS
ALAAFERLQESLAIELAPWNIKVINFQPGPITTELTRFDGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
IDMENPDLCYQSNLFGKQFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ

Sequences:

>Translated_294_residues
MTKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLPNSSNLDVKILDLCDENSIDRFIKEVLS
QYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPLSLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFS
ALAAFERLQESLAIELAPWNIKVINFQPGPITTELTRFDGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
IDMENPDLCYQSNLFGKQFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ
>Mature_293_residues
TKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLPNSSNLDVKILDLCDENSIDRFIKEVLSQ
YQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPLSLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFSA
LAAFERLQESLAIELAPWNIKVINFQPGPITTELTRFDGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEVI
DMENPDLCYQSNLFGKQFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=281, Percent_Identity=26.3345195729537, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI223718074, Length=258, Percent_Identity=27.5193798449612, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI119392083, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7706318, Length=250, Percent_Identity=29.6, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI20149619, Length=211, Percent_Identity=27.4881516587678, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=195, Percent_Identity=28.7179487179487, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787820, Length=210, Percent_Identity=30.4761904761905, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=210, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=236, Percent_Identity=26.271186440678, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=30.4123711340206, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=30.9644670050761, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357041, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=219, Percent_Identity=25.1141552511416, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33038; Mature: 32907

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLPNSSNLDV
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCE
KILDLCDENSIDRFIKEVLSQYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCHH
SLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFSALAAFERLQESLAIELAPWN
HHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCE
IKVINFQPGPITTELTRFDGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
EEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDMENPDLCYQSNLFGKQFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ
HCCCCCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLPNSSNLDV
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCE
KILDLCDENSIDRFIKEVLSQYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCHH
SLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFSALAAFERLQESLAIELAPWN
HHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCE
IKVINFQPGPITTELTRFDGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
EEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDMENPDLCYQSNLFGKQFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ
HCCCCCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]