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The map label for this gene is 52841353

Identifier: 52841353

GI number: 52841353

Start: 1227719

End: 1228783

Strand: Direct

Name: 52841353

Synonym: lpg1119

Alternate gene names: NA

Gene position: 1227719-1228783 (Clockwise)

Preceding gene: 52841350

Following gene: 52841355

Centisome position: 36.13

GC content: 38.69

Gene sequence:

>1065_bases
ATGGTCAACAAGATTTGCCTGAGTTTCGCACTATTAATTAGCGTACCCTCCATTTTATTAGCAGAAGATAAGCTTATTTT
TGCTGTGGACATTATTCGTCATGGCGACAGAACGCCGATTGTTGCTTTGCCTACTGTAAATTACCAATGGCAAGAGGGGC
TTGGCCAGCTTACGGCAGAAGGTATGCAACAAGAATACAAAATGGGTGTGGCATTTCGCAAAAAATATATTGAAGAGTCG
CATTTGTTACCTGAACACTATGAATACGGAACCATCTATGTCCGCTCTACGGATTATGCACGTACTCTGATGAGCGCCCA
GTCATTGTTAATGGGGCTATATCCACCTGGAACTGGACCAACAATTCCTGCAGGAACTTCCGCTTTACCTCATGCTTTTC
AGCCTATTCCCGTATTTAGCGCACCGTCTAAATACGACGAGGTTATTATTCAGCAGGTAGATCGTAAGGAACGGGAAAAG
CTAATGGAGCAATATGTTTTTTCTACCAGGGAGTGGCAACAAAAAAATAATGAATTGAAAGACAAATACCCATTATGGAG
CCGTCTGACTGGTATTAATATTGATAATCTGGGGGATCTGGAAACAGTTGGTCATACCTTATATATTCATCAAATCCATA
ATGCTCCTATGCCGGAAGGATTAGCTTCTAACGATATTGAAACAATTATCAATTCTGCTGAGTGGGCTTTTATGGCACAA
GAAAAACCTCAACAAATAGCGAATGTTTATAGTTCAAAGCTGATGACTAACATAGCTGATTATCTGAATTCCGGAAGCAT
GAAAAAATCTAAACTGAAATATGTTTTGCTATCTGCTCATGATACTACAATTGCCAGTGTATTAAGTTTTTTAGGTGCTC
CTTTGGAAAAATCCCCACCTTATGCCTCAAATGTTAATTTTTCTCTCTATGATAATGGAGCAAATTATTACACAGTAAAA
ATTACCTATAATGGTAATCCGGTTTCTATTCCAGCGTGTGGTGGTTCAGTTTGTGAGTTACAACAGCTTATAAATTTGGT
ACATGATTCTAAAAATTCAGTGTAA

Upstream 100 bases:

>100_bases
TTCGTCATAGTGCGAAACCGAGATTAACCAACGGTGGCAAGATACGACAAGAATTTTTTACGAAGCCTCATGTTTACTTT
AACTCAAGGAGTATGAATAC

Downstream 100 bases:

>100_bases
CTACTCATTCTGGAGGTATTTGGCCGAGGTAAGTAATCCTAACCATCTCAAACTATCTGTTGTTGCAAAACAGCAATAGC
AGCTGGTTTGAGATAATTCA

Product: major acid phosphatase

Products: alcohol; phosphate

Alternate protein names: Acid Phosphatase Map

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MVNKICLSFALLISVPSILLAEDKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAEGMQQEYKMGVAFRKKYIEES
HLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGPTIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREK
LMEQYVFSTREWQQKNNELKDKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQ
EKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHDTTIASVLSFLGAPLEKSPPYASNVNFSLYDNGANYYTVK
ITYNGNPVSIPACGGSVCELQQLINLVHDSKNSV

Sequences:

>Translated_354_residues
MVNKICLSFALLISVPSILLAEDKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAEGMQQEYKMGVAFRKKYIEES
HLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGPTIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREK
LMEQYVFSTREWQQKNNELKDKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQ
EKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHDTTIASVLSFLGAPLEKSPPYASNVNFSLYDNGANYYTVK
ITYNGNPVSIPACGGSVCELQQLINLVHDSKNSV
>Mature_354_residues
MVNKICLSFALLISVPSILLAEDKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAEGMQQEYKMGVAFRKKYIEES
HLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGPTIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREK
LMEQYVFSTREWQQKNNELKDKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQ
EKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHDTTIASVLSFLGAPLEKSPPYASNVNFSLYDNGANYYTVK
ITYNGNPVSIPACGGSVCELQQLINLVHDSKNSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI197116348, Length=339, Percent_Identity=29.7935103244838, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI6382064, Length=347, Percent_Identity=29.971181556196, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI4557010, Length=335, Percent_Identity=28.0597014925373, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI14861860, Length=362, Percent_Identity=27.9005524861878, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI197100230, Length=133, Percent_Identity=40.6015037593985, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI22748649, Length=328, Percent_Identity=22.8658536585366, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI81295410, Length=328, Percent_Identity=22.8658536585366, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565303, Length=336, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17563196, Length=347, Percent_Identity=27.9538904899135, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17536227, Length=294, Percent_Identity=26.8707482993197, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985640, Length=393, Percent_Identity=27.4809160305344, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561236, Length=344, Percent_Identity=25, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI212645396, Length=98, Percent_Identity=42.8571428571429, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531519, Length=399, Percent_Identity=25.5639097744361, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532843, Length=150, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204964, Length=158, Percent_Identity=33.5443037974684, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25152270, Length=350, Percent_Identity=24.8571428571429, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533882, Length=127, Percent_Identity=36.2204724409449, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17864600, Length=374, Percent_Identity=30.7486631016043, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24651231, Length=374, Percent_Identity=30.7486631016043, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666782, Length=347, Percent_Identity=26.5129682997118, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24648840, Length=333, Percent_Identity=27.027027027027, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221512995, Length=337, Percent_Identity=24.0356083086053, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221458312, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.2

Molecular weight: Translated: 39589; Mature: 39589

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00616 HIS_ACID_PHOSPHAT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKICLSFALLISVPSILLAEDKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAE
CCHHHHHHHHHHHHCCHHHEECCCEEEEEEHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
GMQQEYKMGVAFRKKYIEESHLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
TIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREKLMEQYVFSTREWQQKNNELK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQ
CCCCHHHHHCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHCCHHHEEECC
EKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHDTTIASVLSFLGAPLEKSPP
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCC
YASNVNFSLYDNGANYYTVKITYNGNPVSIPACGGSVCELQQLINLVHDSKNSV
CCCCCCEEEEECCCEEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVNKICLSFALLISVPSILLAEDKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAE
CCHHHHHHHHHHHHCCHHHEECCCEEEEEEHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
GMQQEYKMGVAFRKKYIEESHLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
TIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREKLMEQYVFSTREWQQKNNELK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQ
CCCCHHHHHCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHCCHHHEEECC
EKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHDTTIASVLSFLGAPLEKSPP
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCC
YASNVNFSLYDNGANYYTVKITYNGNPVSIPACGGSVCELQQLINLVHDSKNSV
CCCCCCEEEEECCCEEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphate monoester; H2O

Specific reaction: A phosphate monoester + H2O = an alcohol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA