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The map label for this gene is mviN [H]

Identifier: 52841321

GI number: 52841321

Start: 1183472

End: 1185079

Strand: Direct

Name: mviN [H]

Synonym: lpg1087

Alternate gene names: 52841321

Gene position: 1183472-1185079 (Clockwise)

Preceding gene: 52841320

Following gene: 52841322

Centisome position: 34.83

GC content: 38.87

Gene sequence:

>1608_bases
ATGAGTAGTGATAAGACACTAAATGTAAAAGCAACAGGGATCATTGCCCTTGCTGTTATGTGTAGTCGAGTATTAGGTCT
TATTCGAGAAGTCTTATTCAATGCTTTATTTGGCAGTGCTTCCATGGGGATTTTTCTTATCGCATTCCGTGCGCCAAACC
TTTTGAGGGATTTGTTTGCAGAGGGCGCTCTCTCCGTTTCTTTTATTACTGTTTTCTCTAAAAAAATTGAAACTGAAGGA
GAAAAATCAGCTTGGCAGCTGGCTTCAAAAATGCTTACATTGACCAGTGTTTTCATGAGCATCTTATGTCTCTTTGGGAT
TATTTTTGCCAAATACCTCATTTTTATTTTAGCGCCTGGTTTTTCAGTGAAGGATGCTGAAACAACGATTTTCCTCACTC
AATTGATGTTTCCTTTCATTTTATTAGTGTCTCTTGCTGCCATAGTAATGGGGATGCTGAATTCTAAAAATGTTTTTGGT
ATGCCTGCGTTAGCCTCGAGTTTTTTTAACATTGGCTCTATTCTTGGTGGCGCTTTATGTGGATGGTTTATTGATCCATC
ATTTGGAGAGAGGGCACTTATTGGTTTGGCAATCGGAACGGTAATAGGGGGACTTTTACAACTCGGAGTACAATTTCCCA
GCTTAAGAAAGGTTGGTTTTTATTTTAAACCCAATTTTCATTGGTATGATTCTGGGGTTCGAAACACTTTGATTTTAACT
ATTCCAGCAGTGATCGCCGCAAGTGCAGTGCAAATAAATGTACTTATCAATTCAGGATTTGCCTCATACCTTGGAAAAGA
AGCAGTAACATGGCTCAACAGCGCATTTAGACTTATGCAATTTCCACTTGGAGTGTTAGGTGTTGCTATTGCTACGATTA
CATTACCAGTCGTATCTCGTCTTGCTGCAACGAACAATCACTCTCAATTTGGATCAACACTGGCTCGCGCGATCCGTCTA
GCGGTGTTTTTGACAATGCCAGCTGCAGTTGGACTTTGGTTTTTTGCAACCCCCATTATAAGCCTCATTTATGAACACGG
AAAATTTCATGCGTCGGATTCCTTGCAAACCGCATATGCATTGCAATTTTACGCTCTTGGACTTGTGGCTTACTCATGCA
TCAAGGTGCTTTCACCAGCCTTTTACGCCATTGATAAAAAATGGACTCCCATGATTGTCAGTTTTGCAACCATTATCTTA
AATATTATTTTGAATTATTTTTTAATTTTCAAATTGAGTATGGGGCATCGTGGACTCGCTTTGTCCACAACAGTTTCTGC
TACTGTTAATTTTTTGGTTCTATATGTTCTCATGACCCGCTTGCATAATTTGCAGAATAGATACCTTTTCAACACTATAT
TACGGTGTGTTTTAGCATCTGCAATATTAGGTTTTATGTGTCAATCTATCTTTGCGTATGGAGCTGACTTCCTTTACCAT
CCTTCATTTTGGATACGTGCAGTTTCCCTTGCTATTTCAATTTCTTTCGCTGTCTTAGTGTATCTGAGCATGTGTGTAAT
CCTTCGAGTGGATGAGGCAAAGAGTATTTTTATGATCATTCGTCATCGATTAGGATTCCCTATTAAGTTCAAATCAAAAC
AGGTATAA

Upstream 100 bases:

>100_bases
ACACCACAATATCTATTGCATATGCCAAGCATGATAGGGTATCGCTCCTCTTATACTTGGGCTATCATATTAATGTTTTT
GAAGAGACTTTGGATAATCC

Downstream 100 bases:

>100_bases
ACATTAATAATTGAATAATAGAGAAGTTATTGAGAGACTACAGTAGTCTATGAGAAAGTTTGCTTTTATCACAAAGTGAC
TTTGGTTTATCAAACCATTT

Product: virulence factor MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSSDKTLNVKATGIIALAVMCSRVLGLIREVLFNALFGSASMGIFLIAFRAPNLLRDLFAEGALSVSFITVFSKKIETEG
EKSAWQLASKMLTLTSVFMSILCLFGIIFAKYLIFILAPGFSVKDAETTIFLTQLMFPFILLVSLAAIVMGMLNSKNVFG
MPALASSFFNIGSILGGALCGWFIDPSFGERALIGLAIGTVIGGLLQLGVQFPSLRKVGFYFKPNFHWYDSGVRNTLILT
IPAVIAASAVQINVLINSGFASYLGKEAVTWLNSAFRLMQFPLGVLGVAIATITLPVVSRLAATNNHSQFGSTLARAIRL
AVFLTMPAAVGLWFFATPIISLIYEHGKFHASDSLQTAYALQFYALGLVAYSCIKVLSPAFYAIDKKWTPMIVSFATIIL
NIILNYFLIFKLSMGHRGLALSTTVSATVNFLVLYVLMTRLHNLQNRYLFNTILRCVLASAILGFMCQSIFAYGADFLYH
PSFWIRAVSLAISISFAVLVYLSMCVILRVDEAKSIFMIIRHRLGFPIKFKSKQV

Sequences:

>Translated_535_residues
MSSDKTLNVKATGIIALAVMCSRVLGLIREVLFNALFGSASMGIFLIAFRAPNLLRDLFAEGALSVSFITVFSKKIETEG
EKSAWQLASKMLTLTSVFMSILCLFGIIFAKYLIFILAPGFSVKDAETTIFLTQLMFPFILLVSLAAIVMGMLNSKNVFG
MPALASSFFNIGSILGGALCGWFIDPSFGERALIGLAIGTVIGGLLQLGVQFPSLRKVGFYFKPNFHWYDSGVRNTLILT
IPAVIAASAVQINVLINSGFASYLGKEAVTWLNSAFRLMQFPLGVLGVAIATITLPVVSRLAATNNHSQFGSTLARAIRL
AVFLTMPAAVGLWFFATPIISLIYEHGKFHASDSLQTAYALQFYALGLVAYSCIKVLSPAFYAIDKKWTPMIVSFATIIL
NIILNYFLIFKLSMGHRGLALSTTVSATVNFLVLYVLMTRLHNLQNRYLFNTILRCVLASAILGFMCQSIFAYGADFLYH
PSFWIRAVSLAISISFAVLVYLSMCVILRVDEAKSIFMIIRHRLGFPIKFKSKQV
>Mature_534_residues
SSDKTLNVKATGIIALAVMCSRVLGLIREVLFNALFGSASMGIFLIAFRAPNLLRDLFAEGALSVSFITVFSKKIETEGE
KSAWQLASKMLTLTSVFMSILCLFGIIFAKYLIFILAPGFSVKDAETTIFLTQLMFPFILLVSLAAIVMGMLNSKNVFGM
PALASSFFNIGSILGGALCGWFIDPSFGERALIGLAIGTVIGGLLQLGVQFPSLRKVGFYFKPNFHWYDSGVRNTLILTI
PAVIAASAVQINVLINSGFASYLGKEAVTWLNSAFRLMQFPLGVLGVAIATITLPVVSRLAATNNHSQFGSTLARAIRLA
VFLTMPAAVGLWFFATPIISLIYEHGKFHASDSLQTAYALQFYALGLVAYSCIKVLSPAFYAIDKKWTPMIVSFATIILN
IILNYFLIFKLSMGHRGLALSTTVSATVNFLVLYVLMTRLHNLQNRYLFNTILRCVLASAILGFMCQSIFAYGADFLYHP
SFWIRAVSLAISISFAVLVYLSMCVILRVDEAKSIFMIIRHRLGFPIKFKSKQV

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=431, Percent_Identity=36.1948955916473, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 58706; Mature: 58575

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDKTLNVKATGIIALAVMCSRVLGLIREVLFNALFGSASMGIFLIAFRAPNLLRDLFA
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
EGALSVSFITVFSKKIETEGEKSAWQLASKMLTLTSVFMSILCLFGIIFAKYLIFILAPG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSVKDAETTIFLTQLMFPFILLVSLAAIVMGMLNSKNVFGMPALASSFFNIGSILGGALC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GWFIDPSFGERALIGLAIGTVIGGLLQLGVQFPSLRKVGFYFKPNFHWYDSGVRNTLILT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCCCEECCCCCCEEEEE
IPAVIAASAVQINVLINSGFASYLGKEAVTWLNSAFRLMQFPLGVLGVAIATITLPVVSR
HHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAATNNHSQFGSTLARAIRLAVFLTMPAAVGLWFFATPIISLIYEHGKFHASDSLQTAYA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LQFYALGLVAYSCIKVLSPAFYAIDKKWTPMIVSFATIILNIILNYFLIFKLSMGHRGLA
HHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LSTTVSATVNFLVLYVLMTRLHNLQNRYLFNTILRCVLASAILGFMCQSIFAYGADFLYH
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
PSFWIRAVSLAISISFAVLVYLSMCVILRVDEAKSIFMIIRHRLGFPIKFKSKQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure 
SSDKTLNVKATGIIALAVMCSRVLGLIREVLFNALFGSASMGIFLIAFRAPNLLRDLFA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
EGALSVSFITVFSKKIETEGEKSAWQLASKMLTLTSVFMSILCLFGIIFAKYLIFILAPG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSVKDAETTIFLTQLMFPFILLVSLAAIVMGMLNSKNVFGMPALASSFFNIGSILGGALC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GWFIDPSFGERALIGLAIGTVIGGLLQLGVQFPSLRKVGFYFKPNFHWYDSGVRNTLILT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCCCEECCCCCCEEEEE
IPAVIAASAVQINVLINSGFASYLGKEAVTWLNSAFRLMQFPLGVLGVAIATITLPVVSR
HHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAATNNHSQFGSTLARAIRLAVFLTMPAAVGLWFFATPIISLIYEHGKFHASDSLQTAYA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LQFYALGLVAYSCIKVLSPAFYAIDKKWTPMIVSFATIILNIILNYFLIFKLSMGHRGLA
HHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LSTTVSATVNFLVLYVLMTRLHNLQNRYLFNTILRCVLASAILGFMCQSIFAYGADFLYH
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
PSFWIRAVSLAISISFAVLVYLSMCVILRVDEAKSIFMIIRHRLGFPIKFKSKQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]