Click here to switch to the map view.

The map label for this gene is czcC [H]

Identifier: 52841261

GI number: 52841261

Start: 1125522

End: 1126859

Strand: Direct

Name: czcC [H]

Synonym: lpg1027

Alternate gene names: 52841261

Gene position: 1125522-1126859 (Clockwise)

Preceding gene: 52841260

Following gene: 52841262

Centisome position: 33.13

GC content: 44.54

Gene sequence:

>1338_bases
ATGGACTTCCTTGAGTTATTGTTTATGGAATATCATCGTGCTTGGCGGTTTTCTTATCGGGTCGTTCTTCTGTTGCTGTA
CGCCTCTTTGGCAACAGCGGGGAAGGCATGGACTCTTCAGGAAATAACCCAAATGGCTTTTGCAAACAACAAGGATTTAA
AAGCCGCTCGTTATAATGTGGCTATTGCCAAGGCCCGTTTGCTACAAGCTGGCCTTTGGCCCAATCCAAGCCTCAACCTC
TCCAACAACGACGATCGCTTATTTAATGATGAAGGGGAATATTCACGAAGTGCTGGGTTTAATCAAGCATTTCCGATTTC
TGGGCGTATTGCAAAGCAAAAGACAGTGGCGCGCTTAGATGTGTTGAAAGCCATGGCAGAAATCAGGGAAGCAGAGCGCC
AATTAAGCGCCAAAGTAGCGAATGCATTTTATGCCGCGATGATTACTGAGCGTCGCACGCAACAGGTGAATTACTTATTA
CGGATAAACCGAGAGCTCGTTGATGTGATTCATAACCGTTATCACGCGGCTGAAATTTCAAAGCTGGATGAGAATGCGGC
ACGCATTGAGTATCTGCGTATCGGGCAAGAAAAGCACCTTTTGCATAGTCTTCGTATTAGCCAATATGCGCTACTGAATC
AATTGATGGGGCGAGAAGCCAATTCACCCTTATCCCTTAAGATGGATTTTATCGCTGAGAGAACGCTCCTTAAATTACCC
CGCTTAAAAGCCTTGGCGCTTAAAAATCGTCCAGACCGTCAATCCATCGCATTATCGATTGAACGCGCTAATGCCGACAG
GCGTTTGGCCAAAGCCGAGCGTTTTGCTGATTGGACGGTAGGGCTTGGGGTACAACAAGATAAAATTGTGGTCGAAGAGG
GCCCACCTCAACCTGCCGATAGGACTTTGGGTGTGACTCTTTCTGTGCCTCTTCCTCTGTTTAATCGTAATCAGGGGCGA
ATTTTAGAAGCAAGTCACACAGGGACTCAGGCAATAATGGCTTTGCGTGCTTTGAATTTAAGTATTGAGACGGAAGTAAC
CAGTAACTATGGGCAATTAAAAGCGCTGCAAATGAGTCTTAGGGAAACGCAACAGGTTTCTCTGAAATTAGCCGTTGAGA
ATGTCACACTGGCTCGTGACTCTTATGAGAATGGACAAATTTCTTTTTTGAATGTGCTGCAAGTACAAAAACAACAAAAT
GATTTACAAACGACTTATCTCAACACGTTAGAAAAGTATTTGCAAGTGTATGTGGCTTTATGTACAGCTATTGGTCCTGG
TAAAACCAATGGGTTTTGCCCTTATTTAGCGTATCAAAGGAATGGGGATAGTAAATGA

Upstream 100 bases:

>100_bases
GAGTCAACATCAGCAAACTTATGAAGGCAATCCCAAAAATGATTTCGTGGCAGACCATTGGATGGTAGGTCGAGCCTATC
GATGTAAGATAAAACAATAG

Downstream 100 bases:

>100_bases
GATGGCAACAGCGCATGAGAAGGATGGCATTAATTAGTCTGTTTCTTAGTCTACTCGCTCCTATTCAAGGATGCTTTGCT
CATGGGGAAGAAATCGAGGT

Product: chemiosmotic efflux system C protein C

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDFLELLFMEYHRAWRFSYRVVLLLLYASLATAGKAWTLQEITQMAFANNKDLKAARYNVAIAKARLLQAGLWPNPSLNL
SNNDDRLFNDEGEYSRSAGFNQAFPISGRIAKQKTVARLDVLKAMAEIREAERQLSAKVANAFYAAMITERRTQQVNYLL
RINRELVDVIHNRYHAAEISKLDENAARIEYLRIGQEKHLLHSLRISQYALLNQLMGREANSPLSLKMDFIAERTLLKLP
RLKALALKNRPDRQSIALSIERANADRRLAKAERFADWTVGLGVQQDKIVVEEGPPQPADRTLGVTLSVPLPLFNRNQGR
ILEASHTGTQAIMALRALNLSIETEVTSNYGQLKALQMSLRETQQVSLKLAVENVTLARDSYENGQISFLNVLQVQKQQN
DLQTTYLNTLEKYLQVYVALCTAIGPGKTNGFCPYLAYQRNGDSK

Sequences:

>Translated_445_residues
MDFLELLFMEYHRAWRFSYRVVLLLLYASLATAGKAWTLQEITQMAFANNKDLKAARYNVAIAKARLLQAGLWPNPSLNL
SNNDDRLFNDEGEYSRSAGFNQAFPISGRIAKQKTVARLDVLKAMAEIREAERQLSAKVANAFYAAMITERRTQQVNYLL
RINRELVDVIHNRYHAAEISKLDENAARIEYLRIGQEKHLLHSLRISQYALLNQLMGREANSPLSLKMDFIAERTLLKLP
RLKALALKNRPDRQSIALSIERANADRRLAKAERFADWTVGLGVQQDKIVVEEGPPQPADRTLGVTLSVPLPLFNRNQGR
ILEASHTGTQAIMALRALNLSIETEVTSNYGQLKALQMSLRETQQVSLKLAVENVTLARDSYENGQISFLNVLQVQKQQN
DLQTTYLNTLEKYLQVYVALCTAIGPGKTNGFCPYLAYQRNGDSK
>Mature_445_residues
MDFLELLFMEYHRAWRFSYRVVLLLLYASLATAGKAWTLQEITQMAFANNKDLKAARYNVAIAKARLLQAGLWPNPSLNL
SNNDDRLFNDEGEYSRSAGFNQAFPISGRIAKQKTVARLDVLKAMAEIREAERQLSAKVANAFYAAMITERRTQQVNYLL
RINRELVDVIHNRYHAAEISKLDENAARIEYLRIGQEKHLLHSLRISQYALLNQLMGREANSPLSLKMDFIAERTLLKLP
RLKALALKNRPDRQSIALSIERANADRRLAKAERFADWTVGLGVQQDKIVVEEGPPQPADRTLGVTLSVPLPLFNRNQGR
ILEASHTGTQAIMALRALNLSIETEVTSNYGQLKALQMSLRETQQVSLKLAVENVTLARDSYENGQISFLNVLQVQKQQN
DLQTTYLNTLEKYLQVYVALCTAIGPGKTNGFCPYLAYQRNGDSK

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50385; Mature: 50385

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLELLFMEYHRAWRFSYRVVLLLLYASLATAGKAWTLQEITQMAFANNKDLKAARYNV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHH
AIAKARLLQAGLWPNPSLNLSNNDDRLFNDEGEYSRSAGFNQAFPISGRIAKQKTVARLD
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHH
VLKAMAEIREAERQLSAKVANAFYAAMITERRTQQVNYLLRINRELVDVIHNRYHAAEIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLDENAARIEYLRIGQEKHLLHSLRISQYALLNQLMGREANSPLSLKMDFIAERTLLKLP
HHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCC
RLKALALKNRPDRQSIALSIERANADRRLAKAERFADWTVGLGVQQDKIVVEEGPPQPAD
CHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHCCCCCCCCEEEEECCCCCCCC
RTLGVTLSVPLPLFNRNQGRILEASHTGTQAIMALRALNLSIETEVTSNYGQLKALQMSL
CEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
RETQQVSLKLAVENVTLARDSYENGQISFLNVLQVQKQQNDLQTTYLNTLEKYLQVYVAL
HHHHHEEEEEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTAIGPGKTNGFCPYLAYQRNGDSK
HHHCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MDFLELLFMEYHRAWRFSYRVVLLLLYASLATAGKAWTLQEITQMAFANNKDLKAARYNV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHH
AIAKARLLQAGLWPNPSLNLSNNDDRLFNDEGEYSRSAGFNQAFPISGRIAKQKTVARLD
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHH
VLKAMAEIREAERQLSAKVANAFYAAMITERRTQQVNYLLRINRELVDVIHNRYHAAEIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLDENAARIEYLRIGQEKHLLHSLRISQYALLNQLMGREANSPLSLKMDFIAERTLLKLP
HHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCC
RLKALALKNRPDRQSIALSIERANADRRLAKAERFADWTVGLGVQQDKIVVEEGPPQPAD
CHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHCCCCCCCCEEEEECCCCCCCC
RTLGVTLSVPLPLFNRNQGRILEASHTGTQAIMALRALNLSIETEVTSNYGQLKALQMSL
CEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
RETQQVSLKLAVENVTLARDSYENGQISFLNVLQVQKQQNDLQTTYLNTLEKYLQVYVAL
HHHHHEEEEEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTAIGPGKTNGFCPYLAYQRNGDSK
HHHCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]