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The map label for this gene is lspA

Identifier: 52841173

GI number: 52841173

Start: 1015763

End: 1016128

Strand: Direct

Name: lspA

Synonym: lpg0938

Alternate gene names: 52841173

Gene position: 1015763-1016128 (Clockwise)

Preceding gene: 52841172

Following gene: 52841177

Centisome position: 29.9

GC content: 39.07

Gene sequence:

>366_bases
ATGCCAGTTATGCCTATGTTGAATTTCACTTTAGCTTTTAACACAGGCGCTGCTTTTAGTTTTTTAAGCGGCGCAGGCGA
TTGGCATAGGTGGTTTTTTGCAGGGTTTAGTTTTTTAATGAGTATTATTTTGCTGATTTGGTTAGTACGTACTCCAGAAC
AGGCACGATTTCAATCTGTTGGGATAAGTCTTATTCTAGGAGGCGCTATTGGCAACTTGATTGACAGAGGTCTTCATGGT
TATGTGATTGATTTTATTGACGTTTATTATAAACACCACCATTTTGCCACGTTCAACTTGGCCGATAGCGCTATATGTAT
AGGAGCCGCAATTTTAGTTCTGGATTTATTGATTCGTAGGGAATAG

Upstream 100 bases:

>100_bases
TATGAAAAAATGGCCTTGGCTTGTACTTAGTTTTTTAGTAATTATCTGTGATCAGTTAAGTAAGTATTGGGTTGGGGTGT
TGTTAACTCCATATAAACCC

Downstream 100 bases:

>100_bases
ACTCAAACTGCCTAGGAAATAATGTCATAAGTTAGTGTCCTCATGTTTGACTATCCTCTAACAGTCGGGTTTGTGTTCTG
GTTAGATGCAAATAATCCTG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MPVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIWLVRTPEQARFQSVGISLILGGAIGNLIDRGLHG
YVIDFIDVYYKHHHFATFNLADSAICIGAAILVLDLLIRRE

Sequences:

>Translated_121_residues
MPVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIWLVRTPEQARFQSVGISLILGGAIGNLIDRGLHG
YVIDFIDVYYKHHHFATFNLADSAICIGAAILVLDLLIRRE
>Mature_120_residues
PVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIWLVRTPEQARFQSVGISLILGGAIGNLIDRGLHGY
VIDFIDVYYKHHHFATFNLADSAICIGAAILVLDLLIRRE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=115, Percent_Identity=51.304347826087, Blast_Score=125, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 13535; Mature: 13404

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIWLVRTPEQARFQSV
CCCCCCHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GISLILGGAIGNLIDRGLHGYVIDFIDVYYKHHHFATFNLADSAICIGAAILVLDLLIRR
CHHHEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHC
E
C
>Mature Secondary Structure 
PVMPMLNFTLAFNTGAAFSFLSGAGDWHRWFFAGFSFLMSIILLIWLVRTPEQARFQSV
CCCCCHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GISLILGGAIGNLIDRGLHGYVIDFIDVYYKHHHFATFNLADSAICIGAAILVLDLLIRR
CHHHEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA