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The map label for this gene is dapD

Identifier: 52841123

GI number: 52841123

Start: 961062

End: 961892

Strand: Reverse

Name: dapD

Synonym: lpg0888

Alternate gene names: 52841123

Gene position: 961892-961062 (Counterclockwise)

Preceding gene: 52841124

Following gene: 52841122

Centisome position: 28.31

GC content: 39.71

Gene sequence:

>831_bases
ATGAACTCACTTCAAGATCTAATTGAACAAGCCTTTGAAAACCGTCAAAATTTATCGCTCGACACAGCCTCCTCAGATTT
GATCAATGCCATTAATGAAGTTCTCAGTGGTCTGGATAATGGCCAATTCAGAGTCGCTGAAAAAATAAATGGTGAATGGA
CAGTTCATCAATGGCTTAAAAAGGCAGTTCTTTTATCCTTTAAACTTTTCCCAAATCAAATCATAGACGCGGGTTTTTGC
AAGTTTTACGATAAAATACCGCTAAAATATACGGATTGTAGTAATGAGCAATTTCAACAATCAGGGGTAAGAGTTGTTCC
TCATGCCATGGTACGACGTGGAGCATATATTGCCAAAAATACTGTTTTAATGCCTTCTTATGTCAATATAGGTGCTTATA
TTGATGAGGGAGTAATGGTTGATACCTGGGCAACTGTTGGTTCTTGTGCCCAAATAGGAAAAAATGTACATATATCTGGC
GGCGCAGGTATAGGAGGTGTTTTAGAACCATTACAAGCGAACCCAACCATCATTGAGGACAATTGCTTTATTGGTGCCCG
CTCTGAAATAGTGGAAGGGGTTATCGTAGAAAAAAACTCCGTCATATCAATGGGAGTATTTTTAGGCCAAAGCACTAAAA
TCTACAATCGAATCACTGGCGAAGTAAGCTACGGCAGAATTCCGGCTGGCTCAGTAGTTGTTGCAGGTAATTTGCCAAGT
CATGATGGAAGCCACAGTCTATATTGTGCTGTCATTGTGAAACAAGTGGATGAAAAAACTCGCGCGAAGGTAAGCATTAA
TGATTTACTAAGAGCCAATCAAGATGACTGA

Upstream 100 bases:

>100_bases
TCTTATTAACGATTTTCAGGCACAAAATGCATTCAAAGAATGGTTAAATGAACAATGGGCAATAAAAGATAATTTAATAG
CCTCTTTACAGGAATAAAAC

Downstream 100 bases:

>100_bases
TATTAAGCAAATTCTGACTGACCTCATTGGTTTTCCTTCTATTACACCAGAAGATGCTGGCTGCCAAAAATACATGATTC
AATTTCTGGAGCAATTGGGA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNSLQDLIEQAFENRQNLSLDTASSDLINAINEVLSGLDNGQFRVAEKINGEWTVHQWLKKAVLLSFKLFPNQIIDAGFC
KFYDKIPLKYTDCSNEQFQQSGVRVVPHAMVRRGAYIAKNTVLMPSYVNIGAYIDEGVMVDTWATVGSCAQIGKNVHISG
GAGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEKNSVISMGVFLGQSTKIYNRITGEVSYGRIPAGSVVVAGNLPS
HDGSHSLYCAVIVKQVDEKTRAKVSINDLLRANQDD

Sequences:

>Translated_276_residues
MNSLQDLIEQAFENRQNLSLDTASSDLINAINEVLSGLDNGQFRVAEKINGEWTVHQWLKKAVLLSFKLFPNQIIDAGFC
KFYDKIPLKYTDCSNEQFQQSGVRVVPHAMVRRGAYIAKNTVLMPSYVNIGAYIDEGVMVDTWATVGSCAQIGKNVHISG
GAGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEKNSVISMGVFLGQSTKIYNRITGEVSYGRIPAGSVVVAGNLPS
HDGSHSLYCAVIVKQVDEKTRAKVSINDLLRANQDD
>Mature_276_residues
MNSLQDLIEQAFENRQNLSLDTASSDLINAINEVLSGLDNGQFRVAEKINGEWTVHQWLKKAVLLSFKLFPNQIIDAGFC
KFYDKIPLKYTDCSNEQFQQSGVRVVPHAMVRRGAYIAKNTVLMPSYVNIGAYIDEGVMVDTWATVGSCAQIGKNVHISG
GAGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEKNSVISMGVFLGQSTKIYNRITGEVSYGRIPAGSVVVAGNLPS
HDGSHSLYCAVIVKQVDEKTRAKVSINDLLRANQDD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=68.6346863468635, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_LEGPA (Q5X6L6)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123277.1
- ProteinModelPortal:   Q5X6L6
- SMR:   Q5X6L6
- STRING:   Q5X6L6
- GeneID:   3119337
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0949
- LegioList:   lpp0949
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BioCyc:   LPNE297246:LPP0949-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 30079; Mature: 30079

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLQDLIEQAFENRQNLSLDTASSDLINAINEVLSGLDNGQFRVAEKINGEWTVHQWLK
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHH
KAVLLSFKLFPNQIIDAGFCKFYDKIPLKYTDCSNEQFQQSGVRVVPHAMVRRGAYIAKN
HHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCEECCHHHHHCCCEEECC
TVLMPSYVNIGAYIDEGVMVDTWATVGSCAQIGKNVHISGGAGIGGVLEPLQANPTIIED
EEECCCHHCCCEEECCCEEEECHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCCCCEEEC
NCFIGARSEIVEGVIVEKNSVISMGVFLGQSTKIYNRITGEVSYGRIPAGSVVVAGNLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCEEEECCCCC
HDGSHSLYCAVIVKQVDEKTRAKVSINDLLRANQDD
CCCCCCEEHHHHHHHHHHHHHHEEEHHHHHCCCCCC
>Mature Secondary Structure
MNSLQDLIEQAFENRQNLSLDTASSDLINAINEVLSGLDNGQFRVAEKINGEWTVHQWLK
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHH
KAVLLSFKLFPNQIIDAGFCKFYDKIPLKYTDCSNEQFQQSGVRVVPHAMVRRGAYIAKN
HHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCEECCHHHHHCCCEEECC
TVLMPSYVNIGAYIDEGVMVDTWATVGSCAQIGKNVHISGGAGIGGVLEPLQANPTIIED
EEECCCHHCCCEEECCCEEEECHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCCCCEEEC
NCFIGARSEIVEGVIVEKNSVISMGVFLGQSTKIYNRITGEVSYGRIPAGSVVVAGNLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCEEEECCCCC
HDGSHSLYCAVIVKQVDEKTRAKVSINDLLRANQDD
CCCCCCEEHHHHHHHHHHHHHHEEEHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA