Click here to switch to the map view.

The map label for this gene is pntB

Identifier: 52841110

GI number: 52841110

Start: 948674

End: 950095

Strand: Reverse

Name: pntB

Synonym: lpg0874

Alternate gene names: 52841110

Gene position: 950095-948674 (Counterclockwise)

Preceding gene: 52841111

Following gene: 52841109

Centisome position: 27.96

GC content: 42.9

Gene sequence:

>1422_bases
ATGATTTATAGGACGGAATCAGTAATGAATTCAATAGTTCCACTGTTTTATTTATTTGCAGCCATTTGCTTTATATTGGC
TTTAAAAGGACTGGCCAGTCCAGCTACTTCAAGAAGGGGGAACCTTCTAGGCATTCTGGGTATGATCCTGGCAGTGGGCT
CCACCCTGATGATGCCCACTACCTACCATCATATTCTTTTAATCGCCTTAATAGCAGGCGGCGGAATAATAGGAACTATT
ATTGCTTTGAAGATCAACATGACGGCCATACCACAACTGGTTGCTGCTTTTCATTCTTTAGTAGGCATGGCAGCAGTTCT
GGTAGCCTATTGTGCCTTTTTATCCCCCGCGTCCTTTCAAATCGGCACACCTGGTGCTATTGCGACCGCAAGTCTAATTG
AAATGAGCCTGGGATTAATTATCGGAGCCATTACCTTTTCTGGTTCAGTCATTGCCTTTTTAAAATTGCAAGGACTCATA
TCAGGTATTCCAATTCGATTTTATGCTCAAAACTATGTCAACTTACTAATAGGACTAACAATCCTGGTGTTACTCATTTT
ATTTGTAGCCAATCAAAACCTGTTTCTCTTTAACCTGCTCGCGGGATTAGCTTTTCTCATTGGGGTTTTACTGATTATTC
CTATTGGCGGAGCCGATATGCCCGTCGTTATTTCCATGCTGAACTCCTACTCAGGTTGGGCCGCAGCAGGAATAGGTTTC
ACTCTGAGTAATCATCTGTTAGTTATCACAGGCGCTCTGGTAGGCGCCAGCGGGGCAATTTTAAGCTATATCATGTGCGT
TGGTATGAATCGCTCTATTTTTAATGTCATTTTTGGTGGAATAAACAGTTCTGGAAATACGAAACAAGTTCATTCTGCTA
ATGAGTTACGCAATGTCAGGCAAGCCAACGGCGAAGATGCTGCATTCCTATTAAGTAATGCCAAGGATGTCATCATTGTT
CCTGGATATGGAATGGCAGTGGCACATGCTCAACATGCGGTGAAAGAGCTTGTTGATGCCTTGGAATCTCGTTCTATTCG
TGTTCGCTTTGCAATACACCCTGTTGCTGGGCGCATGCCTGGCCATATGAACGTATTACTTGCTGAAGCCAATATCCCCT
ATGACAGAGTCTTTGAGCAAAGTGAAATTAACAGAGATTTTGCTACCTGTGACGTTGCTTACGTGATTGGAGCTAACGAT
ATCACCAACCCCGCAGCTAAAACTGATCCTGCCTCACCCATTTATGGGATGCCTGTCCTGGAGGTTGAAAAAGCTAAAAC
GGTCTTATTCGTCAAACGCAGCTTATCTCCTGGTTATGCCGGTGTAGAAAACGATTTATTTTTTCACGACAATACCTACA
TGCTTTTCGGAGATGCAAAAGTAATGACTGAATCAATAGCTAAGGCTTTGGGAGAAATATAA

Upstream 100 bases:

>100_bases
GCATAACCTGGTTAGGTGGCATAGCCATATTCATTACTTCAATTAATATTTTTGGTGGCTTTGTAGTAACTCAACGCATG
CTTCGCATGTATAAAAAATA

Downstream 100 bases:

>100_bases
CCCTTTCAAAATAAAAACAATAATCTCTGACGGGGTGGGTACCCGGTTCAATCGACGCAAATGCCTTTTAATTTGCCAAC
GAAGCAAAATAAATGTATCT

Product: NAD(P) transhydrogenase subunit beta (pyridine nucleotide transhydrogenase subunit beta)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MIYRTESVMNSIVPLFYLFAAICFILALKGLASPATSRRGNLLGILGMILAVGSTLMMPTTYHHILLIALIAGGGIIGTI
IALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLI
SGIPIRFYAQNYVNLLIGLTILVLLILFVANQNLFLFNLLAGLAFLIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGF
TLSNHLLVITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQVHSANELRNVRQANGEDAAFLLSNAKDVIIV
PGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGAND
ITNPAAKTDPASPIYGMPVLEVEKAKTVLFVKRSLSPGYAGVENDLFFHDNTYMLFGDAKVMTESIAKALGEI

Sequences:

>Translated_473_residues
MIYRTESVMNSIVPLFYLFAAICFILALKGLASPATSRRGNLLGILGMILAVGSTLMMPTTYHHILLIALIAGGGIIGTI
IALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLI
SGIPIRFYAQNYVNLLIGLTILVLLILFVANQNLFLFNLLAGLAFLIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGF
TLSNHLLVITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQVHSANELRNVRQANGEDAAFLLSNAKDVIIV
PGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGAND
ITNPAAKTDPASPIYGMPVLEVEKAKTVLFVKRSLSPGYAGVENDLFFHDNTYMLFGDAKVMTESIAKALGEI
>Mature_473_residues
MIYRTESVMNSIVPLFYLFAAICFILALKGLASPATSRRGNLLGILGMILAVGSTLMMPTTYHHILLIALIAGGGIIGTI
IALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLI
SGIPIRFYAQNYVNLLIGLTILVLLILFVANQNLFLFNLLAGLAFLIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGF
TLSNHLLVITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQVHSANELRNVRQANGEDAAFLLSNAKDVIIV
PGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGAND
ITNPAAKTDPASPIYGMPVLEVEKAKTVLFVKRSLSPGYAGVENDLFFHDNTYMLFGDAKVMTESIAKALGEI

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=479, Percent_Identity=43.6325678496869, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI122939153, Length=479, Percent_Identity=43.6325678496869, Blast_Score=356, Evalue=3e-98,
Organism=Escherichia coli, GI1787886, Length=459, Percent_Identity=52.2875816993464, Blast_Score=434, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17550456, Length=461, Percent_Identity=46.6377440347072, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50134; Mature: 50134

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYRTESVMNSIVPLFYLFAAICFILALKGLASPATSRRGNLLGILGMILAVGSTLMMPT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHCCCC
TYHHILLIALIAGGGIIGTIIALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQ
HHHHHHHHHHHHCCCHHEEHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFYAQNYVNLLIGLT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
ILVLLILFVANQNLFLFNLLAGLAFLIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCH
TLSNHLLVITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQVHSANELRNVR
HHCCCEEEEEHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHCHHHHHHHH
QANGEDAAFLLSNAKDVIIVPGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMP
HCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCC
GHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKTDPASPIYGMPVL
CCCEEEEEECCCCHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCE
EVEKAKTVLFVKRSLSPGYAGVENDLFFHDNTYMLFGDAKVMTESIAKALGEI
EHHCCCEEEEEEECCCCCCCCCCCCEEEECCEEEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYRTESVMNSIVPLFYLFAAICFILALKGLASPATSRRGNLLGILGMILAVGSTLMMPT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHCCCC
TYHHILLIALIAGGGIIGTIIALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQ
HHHHHHHHHHHHCCCHHEEHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFYAQNYVNLLIGLT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
ILVLLILFVANQNLFLFNLLAGLAFLIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCH
TLSNHLLVITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQVHSANELRNVR
HHCCCEEEEEHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHCHHHHHHHH
QANGEDAAFLLSNAKDVIIVPGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMP
HCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCC
GHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKTDPASPIYGMPVL
CCCEEEEEECCCCHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCE
EVEKAKTVLFVKRSLSPGYAGVENDLFFHDNTYMLFGDAKVMTESIAKALGEI
EHHCCCEEEEEEECCCCCCCCCCCCEEEECCEEEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]