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The map label for this gene is dtpA [H]

Identifier: 52840983

GI number: 52840983

Start: 816831

End: 818339

Strand: Reverse

Name: dtpA [H]

Synonym: lpg0746

Alternate gene names: 52840983

Gene position: 818339-816831 (Counterclockwise)

Preceding gene: 52840984

Following gene: 52840973

Centisome position: 24.08

GC content: 38.7

Gene sequence:

>1509_bases
GTGAAATTGATTTCTCAAGCAGTTAAAAATTATCTTCCAGAACTAAGTCTTCGCCAAAAACAAACCAATAATATTATTTT
TATTACTTTTTGGAGCCAGTTTTCTGTCTATGCCTTGAATACAGTTCTGGTTTTATTTTTAACTCGACCCTTGATTGCTC
AGGGATTAGGCTACAGCCAAGCCAAAGCCTACGCTTTCATTGGTGTAACTCAAGCCACAGGCTACCTGATGCCTATTTTA
GGTGGGTATATGGCTGATAATATTGTTGGTGTCAGACGATCCATTCTTTTGGGTAGCATCATGCTGGCTTGTGCTTATTT
ACTGGTCATGTTAAGTGGGTACACCATCAGTTCTCTTGGGGATCAATTATTTATCATAGCTTTTGCCTTTATTCCTGCAA
CCAACTCGCTATTAATGGGAACCGCATCCAGTATGGTTTCTCATATTTATTCCGATGATGCCATTAAAGCCAAATCCGCT
ATGACTTATTACTATATGGCCATTAATGTTGGAGCTCTGCTGGCCACCATGATCGCGCCAGTTCTCCTGGAAAGTCGTTA
TGGTCCACTTTCAGTACTCACCTTAACCTTTATTGGCAAATCGATTGCTGCCTTGAATTTTGCGAAACGTTACTCCATAT
ATGATAGTGTCATCTGGGGTATGGATAAATCCAAATTTTCTAACCAAGGTCTATTGCGCCTTGTTGCTTATATAGCGGCT
ATCTATTCTCTTACTTTATATGCTTATACTCATGTTTATATCGCCAGCACACTGATAGGCGCAGGATGTGCTATAGGAAT
TCTCTGGTTTTTAATTAAAACCATTATGCTTAAAGGCGAAACTCGCAGTAAACAAATGATCGCTGTATTACTGATAATAG
AAGCCATAGTATTTTTTATCATATACAATCAAATGAACAGTACCTTGGTATTATTTGCAGAAAACAATTCTGATCTAAGT
TTTCTTTGGTTTAAAATTTCACCCGCTCAATACCAAATGCTAAATCCTTTGCTCATTTTACTGATTGGAAGTCAACTTCC
CCGTTTCTACAGGTTTTTTTCGCGTTTTACGATCCCCTATCAATTTGCCGCAGGCACAATTCTCTCTGGTATTGCCCTGC
TGGTTATGGCTTTTGCGGCCCAAAATGCAATCAATGGATTAGTGAATGGTAACTACATTGCTTTGACCTACATTTTAATT
TCAATTGCTGAATTATGGGTCAGTGCCATTGGTCTTAGCATGATTGGACTGTATTGTGATGCACGTGCGATTGCCTTTGC
TATGGGCGTATGGTACTTGGCCAGTTCCATGTCCAATGCCATCTCAGGACGAATTGCAGGCTGGGTCGCCATACCAGAGA
ATATTAATTCTGCTCTTGAAAGTTTACCTTATTATAAAAATTATTATTTGATTATGGGCATTAGTGCTTTGGGGCTTGGT
ATTCTGATGTATTTTGTAGCTTATTATTTACACAAGATTATGAAACGACGAGGTATTGAGTTAGCATAA

Upstream 100 bases:

>100_bases
AAATCTTTACTTTTCCCTACCATGACACTCATATTATTGATGTAGTTCTTGCCAGGAAGTGATAATCTTGGGCGGTGGGT
TAGAAAAAACGGAATGAGGT

Downstream 100 bases:

>100_bases
CGTAACTGAACATTGTAATATTCGAATATGCTTCGAGACGGTGCTTCGCACCTCCTCAGCATGAACGGCCTGATGGGAAA
ATCCAATTTTGTAATCAGCC

Product: IraAB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKLISQAVKNYLPELSLRQKQTNNIIFITFWSQFSVYALNTVLVLFLTRPLIAQGLGYSQAKAYAFIGVTQATGYLMPIL
GGYMADNIVGVRRSILLGSIMLACAYLLVMLSGYTISSLGDQLFIIAFAFIPATNSLLMGTASSMVSHIYSDDAIKAKSA
MTYYYMAINVGALLATMIAPVLLESRYGPLSVLTLTFIGKSIAALNFAKRYSIYDSVIWGMDKSKFSNQGLLRLVAYIAA
IYSLTLYAYTHVYIASTLIGAGCAIGILWFLIKTIMLKGETRSKQMIAVLLIIEAIVFFIIYNQMNSTLVLFAENNSDLS
FLWFKISPAQYQMLNPLLILLIGSQLPRFYRFFSRFTIPYQFAAGTILSGIALLVMAFAAQNAINGLVNGNYIALTYILI
SIAELWVSAIGLSMIGLYCDARAIAFAMGVWYLASSMSNAISGRIAGWVAIPENINSALESLPYYKNYYLIMGISALGLG
ILMYFVAYYLHKIMKRRGIELA

Sequences:

>Translated_502_residues
MKLISQAVKNYLPELSLRQKQTNNIIFITFWSQFSVYALNTVLVLFLTRPLIAQGLGYSQAKAYAFIGVTQATGYLMPIL
GGYMADNIVGVRRSILLGSIMLACAYLLVMLSGYTISSLGDQLFIIAFAFIPATNSLLMGTASSMVSHIYSDDAIKAKSA
MTYYYMAINVGALLATMIAPVLLESRYGPLSVLTLTFIGKSIAALNFAKRYSIYDSVIWGMDKSKFSNQGLLRLVAYIAA
IYSLTLYAYTHVYIASTLIGAGCAIGILWFLIKTIMLKGETRSKQMIAVLLIIEAIVFFIIYNQMNSTLVLFAENNSDLS
FLWFKISPAQYQMLNPLLILLIGSQLPRFYRFFSRFTIPYQFAAGTILSGIALLVMAFAAQNAINGLVNGNYIALTYILI
SIAELWVSAIGLSMIGLYCDARAIAFAMGVWYLASSMSNAISGRIAGWVAIPENINSALESLPYYKNYYLIMGISALGLG
ILMYFVAYYLHKIMKRRGIELA
>Mature_502_residues
MKLISQAVKNYLPELSLRQKQTNNIIFITFWSQFSVYALNTVLVLFLTRPLIAQGLGYSQAKAYAFIGVTQATGYLMPIL
GGYMADNIVGVRRSILLGSIMLACAYLLVMLSGYTISSLGDQLFIIAFAFIPATNSLLMGTASSMVSHIYSDDAIKAKSA
MTYYYMAINVGALLATMIAPVLLESRYGPLSVLTLTFIGKSIAALNFAKRYSIYDSVIWGMDKSKFSNQGLLRLVAYIAA
IYSLTLYAYTHVYIASTLIGAGCAIGILWFLIKTIMLKGETRSKQMIAVLLIIEAIVFFIIYNQMNSTLVLFAENNSDLS
FLWFKISPAQYQMLNPLLILLIGSQLPRFYRFFSRFTIPYQFAAGTILSGIALLVMAFAAQNAINGLVNGNYIALTYILI
SIAELWVSAIGLSMIGLYCDARAIAFAMGVWYLASSMSNAISGRIAGWVAIPENINSALESLPYYKNYYLIMGISALGLG
ILMYFVAYYLHKIMKRRGIELA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=487, Percent_Identity=29.9794661190965, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1789911, Length=476, Percent_Identity=28.3613445378151, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1790572, Length=402, Percent_Identity=23.3830845771144, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786927, Length=417, Percent_Identity=21.8225419664269, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55474; Mature: 55474

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLISQAVKNYLPELSLRQKQTNNIIFITFWSQFSVYALNTVLVLFLTRPLIAQGLGYSQ
CCHHHHHHHHHCCCCHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCH
AKAYAFIGVTQATGYLMPILGGYMADNIVGVRRSILLGSIMLACAYLLVMLSGYTISSLG
HHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
DQLFIIAFAFIPATNSLLMGTASSMVSHIYSDDAIKAKSAMTYYYMAINVGALLATMIAP
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLESRYGPLSVLTLTFIGKSIAALNFAKRYSIYDSVIWGMDKSKFSNQGLLRLVAYIAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHH
IYSLTLYAYTHVYIASTLIGAGCAIGILWFLIKTIMLKGETRSKQMIAVLLIIEAIVFFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IYNQMNSTLVLFAENNSDLSFLWFKISPAQYQMLNPLLILLIGSQLPRFYRFFSRFTIPY
HHHCCCCEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCH
QFAAGTILSGIALLVMAFAAQNAINGLVNGNYIALTYILISIAELWVSAIGLSMIGLYCD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAIAFAMGVWYLASSMSNAISGRIAGWVAIPENINSALESLPYYKNYYLIMGISALGLG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEEHHHHHHH
ILMYFVAYYLHKIMKRRGIELA
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLISQAVKNYLPELSLRQKQTNNIIFITFWSQFSVYALNTVLVLFLTRPLIAQGLGYSQ
CCHHHHHHHHHCCCCHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCH
AKAYAFIGVTQATGYLMPILGGYMADNIVGVRRSILLGSIMLACAYLLVMLSGYTISSLG
HHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
DQLFIIAFAFIPATNSLLMGTASSMVSHIYSDDAIKAKSAMTYYYMAINVGALLATMIAP
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLESRYGPLSVLTLTFIGKSIAALNFAKRYSIYDSVIWGMDKSKFSNQGLLRLVAYIAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHH
IYSLTLYAYTHVYIASTLIGAGCAIGILWFLIKTIMLKGETRSKQMIAVLLIIEAIVFFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IYNQMNSTLVLFAENNSDLSFLWFKISPAQYQMLNPLLILLIGSQLPRFYRFFSRFTIPY
HHHCCCCEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCH
QFAAGTILSGIALLVMAFAAQNAINGLVNGNYIALTYILISIAELWVSAIGLSMIGLYCD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAIAFAMGVWYLASSMSNAISGRIAGWVAIPENINSALESLPYYKNYYLIMGISALGLG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEEHHHHHHH
ILMYFVAYYLHKIMKRRGIELA
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA