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The map label for this gene is alaS

Identifier: 52840846

GI number: 52840846

Start: 641653

End: 642426

Strand: Reverse

Name: alaS

Synonym: lpg0609

Alternate gene names: 52840846

Gene position: 642426-641653 (Counterclockwise)

Preceding gene: 52840847

Following gene: 52840845

Centisome position: 18.91

GC content: 39.02

Gene sequence:

>774_bases
ATGGGCTTTGTCACTCATTCCATTCTGTGCCTTATGCGGCAGTTTGCTTATTGTATTAATTCATATCAAAACAAGAGCTT
ATGCAGCCCCAGAGCTTATGAAAAAGACTTCATTGACGGGAGTGTAGCTATGGAAAAAATTTTTTGGTCTAATCCCTACC
AGCATACACTCGATACCAAGATAATCTCAATTAATGGCAACGAGATTCTATTAGAAAAAACCATCGCGTTTTCATTTTCA
GGAGGACAGGAAAGCGATAGAGCATTTATCAATGGCCTTGAAGTACTCAGTTCACGAATAGATGGAAATCTTATTTATTA
TACCCTGCCTGATGACCATAATCTTGCGCCCAATGATGTAATCACCATGACTATAGATTGGCCTCGAAGACACCGGCTGA
TGCGTCTTCATTTTGCAGCAGAACTGATTCTGGAACTTGTAACCAGAACCAGTATGCTTGAAAAAGTAGGAGCTCACATC
TCAGAATCCAAAGCTCGAATAGATTTTAAAGCGAATTTTAATATCTCTTCTATTTTTAGCCAGCTGCTTGATGAATATAA
TGCCATCATTAGACAAGATCTTGTTATCTATAAAGGATACCATGATGTGACAAATCAACGTCGGTTTTGGAAAATTGACG
GTTTTGCTGAAGTACCTTGTGGGGGAACACATGTTCATTCCACTTCTGAAGTGGGTTTTATTCGTCTCAAACGCTCGCAT
CCTGGCAAATCTATTGAACGCATTGAAATAACCCTGATGGATGATAGTAGATAA

Upstream 100 bases:

>100_bases
GGTCTTTTTTCCATACTTTGATTGGTAAATTAATGGATAGCAGTTGGAGCGGGCAAATGAGCGCTAATGGACTTAAATTA
TATGAAATGGAATCGTATCA

Downstream 100 bases:

>100_bases
TGCACCCCTCGCATAAGCTGATTGTTTTGCTTTGGGGCAAGGTGAGAATGTTATGGGGCAATGAGTTTATATACATTGAA
TGAACGTTGCTGAAACGTTT

Product: alanyl tRNA synthetase

Products: NA

Alternate protein names: AlaX-M; Alanyl-tRNA deacylase AlaX-M [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MGFVTHSILCLMRQFAYCINSYQNKSLCSPRAYEKDFIDGSVAMEKIFWSNPYQHTLDTKIISINGNEILLEKTIAFSFS
GGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDVITMTIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHI
SESKARIDFKANFNISSIFSQLLDEYNAIIRQDLVIYKGYHDVTNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSH
PGKSIERIEITLMDDSR

Sequences:

>Translated_257_residues
MGFVTHSILCLMRQFAYCINSYQNKSLCSPRAYEKDFIDGSVAMEKIFWSNPYQHTLDTKIISINGNEILLEKTIAFSFS
GGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDVITMTIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHI
SESKARIDFKANFNISSIFSQLLDEYNAIIRQDLVIYKGYHDVTNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSH
PGKSIERIEITLMDDSR
>Mature_256_residues
GFVTHSILCLMRQFAYCINSYQNKSLCSPRAYEKDFIDGSVAMEKIFWSNPYQHTLDTKIISINGNEILLEKTIAFSFSG
GQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDVITMTIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHIS
ESKARIDFKANFNISSIFSQLLDEYNAIIRQDLVIYKGYHDVTNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSHP
GKSIERIEITLMDDSR

Specific function: Functions in trans to edit the amino acid moiety from mischarged charged Gly-tRNA(Ala) and Ser-tRNA(Ala) [H]

COG id: COG2872

COG function: function code R; Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-M subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018165
- InterPro:   IPR018164
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF01411 tRNA-synt_2c; PF07973 tRNA_SAD [H]

EC number: NA

Molecular weight: Translated: 29515; Mature: 29384

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFVTHSILCLMRQFAYCINSYQNKSLCSPRAYEKDFIDGSVAMEKIFWSNPYQHTLDTK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCEECCEE
IISINGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDV
EEEECCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCE
ITMTIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISESKARIDFKANFNISSIFS
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHH
QLLDEYNAIIRQDLVIYKGYHDVTNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSH
HHHHHHHHHHHHHHEEECCCHHHCCCCEEEEECCEEECCCCCCEECCCCCCEEEEEECCC
PGKSIERIEITLMDDSR
CCCCEEEEEEEEECCCC
>Mature Secondary Structure 
GFVTHSILCLMRQFAYCINSYQNKSLCSPRAYEKDFIDGSVAMEKIFWSNPYQHTLDTK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCEECCEE
IISINGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDV
EEEECCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCE
ITMTIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISESKARIDFKANFNISSIFS
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHH
QLLDEYNAIIRQDLVIYKGYHDVTNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSH
HHHHHHHHHHHHHHEEECCCHHHCCCCEEEEECCEEECCCCCCEECCCCCCEEEEEECCC
PGKSIERIEITLMDDSR
CCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]