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The map label for this gene is rlmM [H]

Identifier: 52840845

GI number: 52840845

Start: 640492

End: 641406

Strand: Reverse

Name: rlmM [H]

Synonym: lpg0608

Alternate gene names: 52840845

Gene position: 641406-640492 (Counterclockwise)

Preceding gene: 52840846

Following gene: 52840836

Centisome position: 18.88

GC content: 40.87

Gene sequence:

>915_bases
ATGGAACTGCCCTATCATTTCTCTACTGCCTATGTGTCAAAACCAGAGTTTATAGAAGCACTTTCTGAGGAGTTAGGCGA
GGTATCCAATAAAATAGGCTCTCTCGTTTTTTCTCCTCATCAGAAGCTTGATGTTTGTTTTGCACTGGATGTATGGCTTG
AACCTGAGATAGTAACCTTTCAATCCATTTCAGAAGCAGCAAAAATATTGAGGCAAGCCGGAAAATTCTGGTATTTGCAC
CCTGTTACTGAAATTCGCCGATCGCGCTTGATTGAGGAACAACTTCGCAAGTGCCCATCACTAATGTCCCATTTTCCAGT
TACAAGTGACATTCCACCCATAGGTGTATTTAGTCTTCTTGATAGAAACACTCTACTCTTTAGCGCCAAACGACTAAAAA
AATGGCCGGATGGACAATGTTATTTTATTGAAGACAAAGTCAATCCCCCAAACCGGGCTTATTTAAAATTATGGGAAGCC
TTGTTCCTGTTAAATAAATACCCTCTCCCTGGTGAAACAGTTTTAGATTTGGGCGCATCCCCGGGAGGTTGGACATATGT
GATGCAATCACTCGGAACCCAAGTCACTTCGGTCGACAAAGCAGAACTGGATACAAAAATCATGGCGCTTCCCAGAGTCA
GTTTTTTAAAGCAAAGCGCCTTTGCCCTAGATCCCGAACAACTCACAGAGTCTTATGACTGGGTACTTTCCGATGTTGCC
TGCTATCCTGACAGAGCCTACACCCTCATCAAAAAATGGATAGCATCAAAAAAAGCAAAACAGTTGATTTTTACCATCAA
ACTACAGGGGCAAACTGACTTAAACACAATCAAACGATTTCAATCCATACCTAATTCCAAAGTAATCAATCTGTTTTATA
ACAAACATGAAGTCACGTTTTTTTATCCAGTATAA

Upstream 100 bases:

>100_bases
GTCAAGCGCTAATCGAGACAAAAATATAGAAAAAGAATACAAAATCGCCTAAATTACAGCATTTGACTTTGTCGCCATTA
ACCTGTGAGCGTTATTTATC

Downstream 100 bases:

>100_bases
ACATAACCAGGATTTAGTGATTATGTCTGCAAAAATATCTTAATGACGAGCTAATATTTAATTTTCTATGACTTAAGACC
TTGAAAAATCAAATGAGAGA

Product: SAM-dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MELPYHFSTAYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEA
LFLLNKYPLPGETVLDLGASPGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTFFYPV

Sequences:

>Translated_304_residues
MELPYHFSTAYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEA
LFLLNKYPLPGETVLDLGASPGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTFFYPV
>Mature_304_residues
MELPYHFSTAYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEA
LFLLNKYPLPGETVLDLGASPGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTFFYPV

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=128, Percent_Identity=28.125, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 34867; Mature: 34867

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPYHFSTAYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTF
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCEEHH
QSISEAAKILRQAGKFWYLHPVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLL
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEALFLLNKYPLPGETVLDLGAS
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
PGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTF
HCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCEEEEE
FYPV
EECC
>Mature Secondary Structure
MELPYHFSTAYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTF
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCEEHH
QSISEAAKILRQAGKFWYLHPVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLL
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEALFLLNKYPLPGETVLDLGAS
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
PGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGQTDLNTIKRFQSIPNSKVINLFYNKHEVTF
HCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCEEEEE
FYPV
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA