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The map label for this gene is dinP

Identifier: 52840797

GI number: 52840797

Start: 594470

End: 595537

Strand: Reverse

Name: dinP

Synonym: lpg0554

Alternate gene names: 52840797

Gene position: 595537-594470 (Counterclockwise)

Preceding gene: 52840798

Following gene: 52840796

Centisome position: 17.53

GC content: 41.29

Gene sequence:

>1068_bases
ATGAATCCGATTAGAAAAATTATCCATATTGATATGGACTGTTTTTATGCGGCAATTGAAATGCGTGATTTCCCTGAGCT
GGCAAATAAACCTATCGCTGTAGGCGGGGATGCAAAACGTCGTGGAGTTATAGCGACCTGTAACTATGCTGCCCGCCAAT
TTGGCATACGCTCTGCAATGCCAACAGCCCATGCGCTTAAACTTTGCCGAGAGTTAATCTTGCGGCCAGTACGTATGGAT
GTATACCAAAAGGAAAGCCAATATATTAGATCCCTATTAACAGAATATACGGACCTCATTGAACCTTTATCATTAGATGA
AGCCTATCTGGATGTCACTGAATCCACACAATGCCAGGGAAGCGCCACCTGGATTGCTGAAGAAATACGCGCCCGAATTT
ATCAAGCAAGACAACTCACTGCGAGTGCGGGCATTGCGCCAAATAAGAGTCTCGCAAAAATAGCCAGTGATTGGCATAAA
CCGAATGGGCAAATGGTTATTAGACCTGAGGACGTTAGCGCATTTGTTCTTGATTTACCAGTACGCAAGTTATTTGGCGT
AGGGCCCAAGATGGAGGAAAAATTGAGGGCGCTCAATATTAAAACCTGTGCTGATTTGCAGCGATATTCCATTGAATATT
TATTACAAAAATTTGGCACCATGGGTCAAAGACTTTATGAATTAGCGCGAGGCATTGATAATCGCCCCGTCAATCCTGAG
CGTATTCGAAAATCCATCAGCGTTGAAGAAACCTATCCAAAAGACTTGCCAAATAGTGAAGCTTGCCTGGCAGTCTTGCC
AGATCTTATGGCGCGCCTTGAAGCAAGAATACAACGTGCAGGTAAAATTTCTGGCATTCACAATTTATTTGTAAAATTGA
AGTTTAATGACTTTCAGCAAACAACTATTGAACGAGTTATGGACAAACTTGATTTAATCGTTTTACGCCAATTGATACAA
GAAGGTTTTGCCAGAAGAGGAATGCCAGTACGATTATTAGGTATAGGAATTAAATTGAAACAAGAAAATACGTATCAAAG
CGTACAATTGCCATTACTTGACTTATAA

Upstream 100 bases:

>100_bases
AAGTAAAAAATAGTTATTCTGTAGACTAAACTTTACAGCTTCAAGAAAGTCGGCTAAGGCCTAATATGAAATCTCTGTTA
TTGCAATCTGTGATTGAAAA

Downstream 100 bases:

>100_bases
CAAGTATCTAAACAGTTGATATCAGATTCTTTCCCAAACTTGCCATAATTATCAGAACTTAATACATCAACTCTCTTTTT
TATGCGACACCCTGCAATAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQARQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLRALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKLDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL

Sequences:

>Translated_355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQARQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLRALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKLDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
>Mature_355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQARQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLRALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKLDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=328, Percent_Identity=32.6219512195122, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI7706681, Length=329, Percent_Identity=32.5227963525836, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI154350220, Length=315, Percent_Identity=31.4285714285714, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=49.0740740740741, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI5729982, Length=321, Percent_Identity=28.0373831775701, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786425, Length=340, Percent_Identity=52.6470588235294, Blast_Score=338, Evalue=5e-94,
Organism=Escherichia coli, GI1787432, Length=229, Percent_Identity=29.6943231441048, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=398, Percent_Identity=31.9095477386935, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=29.3436293436293, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=343, Percent_Identity=29.4460641399417, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324921, Length=272, Percent_Identity=28.6764705882353, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=30.3405572755418, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=31.2280701754386, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=31.2280701754386, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=36.9747899159664, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40375; Mature: 40375

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAM
CCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCEEEECHHHHHHHHHHHCC
PTAHALKLCRELILRPVRMDVYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
SATWIAEEIRARIYQARQLTASAGIAPNKSLAKIASDWHKPNGQMVIRPEDVSAFVLDLP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VRKLFGVGPKMEEKLRALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
HHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHH
TTIERVMDKLDLIVLRQLIQEGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAM
CCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCEEEECHHHHHHHHHHHCC
PTAHALKLCRELILRPVRMDVYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
SATWIAEEIRARIYQARQLTASAGIAPNKSLAKIASDWHKPNGQMVIRPEDVSAFVLDLP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VRKLFGVGPKMEEKLRALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
HHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHH
TTIERVMDKLDLIVLRQLIQEGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA