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The map label for this gene is 52840715

Identifier: 52840715

GI number: 52840715

Start: 512912

End: 513922

Strand: Reverse

Name: 52840715

Synonym: lpg0470

Alternate gene names: NA

Gene position: 513922-512912 (Counterclockwise)

Preceding gene: 52840716

Following gene: 52840713

Centisome position: 15.13

GC content: 40.16

Gene sequence:

>1011_bases
ATGAGTTATGAAGAATTATCAAATACCATGGAGCAAATGCTGCATGAAGGAAAAGGTATTTTAGCTGCAGATGAAAGCAA
CAGTACAATTGGCAAACGCTTTGCGTCAATCAATACAGAAAATACCGAGGAAAATCGAAGAGATTATCGCTTGTTACTAG
CGACCACTCCTGATTTAGAACAGTATATCAACGGCGTCATTTTATTTGAGGAAACTTTTACTCAAACTGATGAGCATGGA
ACACCAATTCCTGAGCTTTTTGCTAATAAAGGCATTATTCCTGGAATTAAAGTAGACAAAGGGCTTGTTGATTTAGCCAA
TACAGAACATGAAAAAGTTACCCAGGGATTAGATGGTTTAACTGAGCGTCTACTTCATTTTAAAAAATTAGGTGCAAAAT
TCGCAAAATGGAGAAACGTTTATTCAATTTCCGAATACACTCCCAGCCTAACTGCAATCAAAACAGGAGCTGAAAATTTG
GGCCGTTACGCTGCTGCTTGTCAATCAGTCGGCATCGTCCCAATTGTTGAGCCTGAAGTATTAATGGATGGCAACCATAG
CATAGAACATTGTGCAGAAGTCTGTGAAATGGTTCTCCATGAGCTGTTTCATACCTTGTTTATCCATCAAGTGGAGTTGG
AGCATATTATACTTAAACCGAGTATGGTTACCTGTGGTAAAGAAGTGGCCCCGTTTAGCGATCCTGAAGAAGTGGCTGAC
TACACCATTAGTGTATTTCGTAATAATGTTCCAGCGTCAGTACCCACCATTAATTTCCTCTCCGGTGGCCAAACACCCCA
ACAGGCTACCGCTAACTTGAATGCAATCAATCAAATTGGCCACCAACCCTGGTTATTAAGTTTTTCATTTGGAAGAGCAT
TACAAGAGGATTGCTTAAAGGAATGGTGTGGAAACAAAGCAAATATTGCCAAAGCGCAAGAGGCTTTAATTAAGAGAGCC
CGCTTAAACAGTATGGCTTGTTTGGGTGAATACCAAAACGACATGGAGTAA

Upstream 100 bases:

>100_bases
AACCCGGATTTGACAAAAGATGACTAATCGTTATTTAAATTTAATAGGTGCCAAACCACTTCGAAAGGTCGACACCCGAT
AATGAGGAGATAAAGACGCT

Downstream 100 bases:

>100_bases
AGTTGCAATAGCGACAGAACCTTCTCTCGACCAGGAAGGCTGTCGCTTTAATTTTAATCATACAAGGCTTGCTAAAAACC
CCATGGTCAAGGCAAAAAAT

Product: fructose bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLEQYINGVILFEETFTQTDEHG
TPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGLTERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENL
GRYAAACQSVGIVPIVEPEVLMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVAPFSDPEEVAD
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLKEWCGNKANIAKAQEALIKRA
RLNSMACLGEYQNDME

Sequences:

>Translated_336_residues
MSYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLEQYINGVILFEETFTQTDEHG
TPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGLTERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENL
GRYAAACQSVGIVPIVEPEVLMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVAPFSDPEEVAD
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLKEWCGNKANIAKAQEALIKRA
RLNSMACLGEYQNDME
>Mature_335_residues
SYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLEQYINGVILFEETFTQTDEHGT
PIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGLTERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENLG
RYAAACQSVGIVPIVEPEVLMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVAPFSDPEEVADY
TISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLKEWCGNKANIAKAQEALIKRAR
LNSMACLGEYQNDME

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=330, Percent_Identity=51.8181818181818, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI34577110, Length=330, Percent_Identity=51.8181818181818, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI4557305, Length=330, Percent_Identity=51.8181818181818, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI193794814, Length=330, Percent_Identity=51.8181818181818, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI4885063, Length=335, Percent_Identity=49.5522388059701, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI40354205, Length=330, Percent_Identity=48.4848484848485, Blast_Score=301, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI25150450, Length=331, Percent_Identity=51.0574018126888, Blast_Score=331, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI71983985, Length=330, Percent_Identity=51.2121212121212, Blast_Score=323, Evalue=9e-89,
Organism=Caenorhabditis elegans, GI71983990, Length=235, Percent_Identity=50.2127659574468, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI45553577, Length=330, Percent_Identity=51.2121212121212, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24650282, Length=330, Percent_Identity=50.6060606060606, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24650280, Length=330, Percent_Identity=50.6060606060606, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24650278, Length=330, Percent_Identity=50.6060606060606, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI221459619, Length=330, Percent_Identity=50.6060606060606, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI24650288, Length=330, Percent_Identity=50.6060606060606, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI24650304, Length=330, Percent_Identity=44.5454545454545, Blast_Score=275, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37381; Mature: 37250

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLE
CCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCHHCCCCEEEEEECCCCHH
QYINGVILFEETFTQTDEHGTPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGL
HHHCCEEEEEHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHH
TERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENLGRYAAACQSVGIVPIVEPEV
HHHHHHHHHHHHHHHHHHCCEEHHHCCCCHHHHHHCHHHHHHHHHHHHHCCCEEECCCHH
LMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVAPFSDPEEVAD
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCCCCCCCCHHHHHH
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLK
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
EWCGNKANIAKAQEALIKRARLNSMACLGEYQNDME
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLE
CHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCHHCCCCEEEEEECCCCHH
QYINGVILFEETFTQTDEHGTPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGL
HHHCCEEEEEHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHH
TERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENLGRYAAACQSVGIVPIVEPEV
HHHHHHHHHHHHHHHHHHCCEEHHHCCCCHHHHHHCHHHHHHHHHHHHHCCCEEECCCHH
LMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVAPFSDPEEVAD
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCCCCCCCCHHHHHH
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLK
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
EWCGNKANIAKAQEALIKRARLNSMACLGEYQNDME
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]