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The map label for this gene is oxaA

Identifier: 39998555

GI number: 39998555

Start: 3811508

End: 3813103

Strand: Reverse

Name: oxaA

Synonym: GSU3466

Alternate gene names: 39998555

Gene position: 3813103-3811508 (Counterclockwise)

Preceding gene: 39998556

Following gene: 39998554

Centisome position: 99.97

GC content: 56.45

Gene sequence:

>1596_bases
ATGGAAAAAAGGGCTTTGATAGCTGTTGTACTATCCATTCTCTTCTTTTACGGCTACACGGCACTCTTTTCGCCGCCCCC
GAAAGAAACACCGAAGCCGGTTGCCACTGCGACGCAAAGCCAGCCGGCTCAGCAGGTGACTGCCGCACCGGTTCCCGTGG
CTGTTCCCGCTCAGCCTCAACCGGCTGTTGCCGCCAGGGACGTGTCGGTCGACACTCCTGCCTATTCGGTGACGTTTTCC
ACCCAGGGCGGGAGTATTAAGCGCCTCGATCTGAAGCGGTATCATGAGACGGCTGGTCCGGGCGGCAAGAACGTCACGCT
GGTTTCCGAGGACAATCCGTCGAATTACACCATTGGCCTCCGCGCTCCCGGTTTCGGTCTTGACCAGAATGCAGTCTTTG
TCCCGAGTGCCGACGCACTCACCGTAGGACCCGGCGAGAAGAAGCAGCTTTCCTTCACCTGGGTTTCGCCGGCCGGCGTC
ACGGTGACAAAGACATATAACTTTTCCGGTGACGGCTACGGGCTGGAGATACAGTACCAGGTCACCAACAGCGGCAGCGC
TCGCGTATCCTCGCCTGTTCAGACGGTCCAGACCTATCCCCTTGTGCCAAAGGTCAAGGAGAGCAGGTTTGAGACCTTCG
GACCGGCGACCTTTGCCCAGGACAAACTGTTTGAGGACAAGGTGAAGGACCTGGAGTCGGGCGCAAAGACTCATGCGGCT
CCGCTCTGGTCCGGATTCGCTGACAAGTACTTCCTCTCTGCCGTACTGGCTCACGAGGGTAGTATGGCGGCAGCAACCAT
CCGCAAGACAGCCTCGGGTTATCTGGAGAACACCATCTCTTCACCTGAACTGTCCCTTAACCCCGGTGAGGGCCGGGCGC
TTACCTATCGTCTTTTCTTCGGGCCCAAGGATATCGATGTTCTCAAGGCACAGGGCAACAGCCTGGAGCGGGCGATCAAC
CTGGGCTGGTTCGCGATGCTGGCTAAGCCCCTTCTCCACAGTCTCAAGTTTTTCCACAACTACACCGGGAACTACGGGAT
AGCCATTATCATCATCACGGTTATCATAAAGGTTATCTTCTACCCGCTAACCCACTCCAGCTACAAGTCCATGAAGGAGA
TGCAGAAGCTCCAGCCGAAGATGCAGCAGTTGCGCGAAAAGTACAAGAATGACCGTGAGGCCATGAACCGCGCCATGATG
GAACTGTACCAGACCCATAAGGTGAACCCTGTGGGCGGGTGTCTCCCCATGCTCGTACAGATTCCCGTCTTCTTCGCGCT
CTACAAGGCGCTCATGTTCTCCATTGAGTTGCGCCACGCGCCCTTCATGCTCTGGATCACCGATCTGGCCGCCAAGGATC
CCTACTACGTGACTCCCATCATCATGGGTGTGACAATGGTCATCCAGCAGAAGATGACGCCTTCCCAAATGGATCCTGTG
CAGCAGAAGATGATGATGGCGCTGCCGGTGGTCTTTACGTTCATGTTCCTCAACTTCCCGTCGGGCCTTGTGCTTTACTG
GCTCGTCAACAACGTGCTTACCATCATTCAGCAGTACTACATCAACCGCAGCATCAGTACGGCGGAGGCCAAGTAG

Upstream 100 bases:

>100_bases
GTTAAGGGACTCTGGCTTACTACTATCCGGATCCTCAAGTGTCATCCATTCCATCCGGGCGGCGTTGATCCAGTCAAGTA
ACGAATAATCAGGAGCTGAC

Downstream 100 bases:

>100_bases
CGGACCATGTACGTGGAAGATACCATAGCCGCCATCAGCACGGCGGCAGGGGAGGGTGGGGTCGGGATCGTCCGCGTTAG
CGGACCGGACGCCCCCTCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MEKRALIAVVLSILFFYGYTALFSPPPKETPKPVATATQSQPAQQVTAAPVPVAVPAQPQPAVAARDVSVDTPAYSVTFS
TQGGSIKRLDLKRYHETAGPGGKNVTLVSEDNPSNYTIGLRAPGFGLDQNAVFVPSADALTVGPGEKKQLSFTWVSPAGV
TVTKTYNFSGDGYGLEIQYQVTNSGSARVSSPVQTVQTYPLVPKVKESRFETFGPATFAQDKLFEDKVKDLESGAKTHAA
PLWSGFADKYFLSAVLAHEGSMAAATIRKTASGYLENTISSPELSLNPGEGRALTYRLFFGPKDIDVLKAQGNSLERAIN
LGWFAMLAKPLLHSLKFFHNYTGNYGIAIIIITVIIKVIFYPLTHSSYKSMKEMQKLQPKMQQLREKYKNDREAMNRAMM
ELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWITDLAAKDPYYVTPIIMGVTMVIQQKMTPSQMDPV
QQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQYYINRSISTAEAK

Sequences:

>Translated_531_residues
MEKRALIAVVLSILFFYGYTALFSPPPKETPKPVATATQSQPAQQVTAAPVPVAVPAQPQPAVAARDVSVDTPAYSVTFS
TQGGSIKRLDLKRYHETAGPGGKNVTLVSEDNPSNYTIGLRAPGFGLDQNAVFVPSADALTVGPGEKKQLSFTWVSPAGV
TVTKTYNFSGDGYGLEIQYQVTNSGSARVSSPVQTVQTYPLVPKVKESRFETFGPATFAQDKLFEDKVKDLESGAKTHAA
PLWSGFADKYFLSAVLAHEGSMAAATIRKTASGYLENTISSPELSLNPGEGRALTYRLFFGPKDIDVLKAQGNSLERAIN
LGWFAMLAKPLLHSLKFFHNYTGNYGIAIIIITVIIKVIFYPLTHSSYKSMKEMQKLQPKMQQLREKYKNDREAMNRAMM
ELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWITDLAAKDPYYVTPIIMGVTMVIQQKMTPSQMDPV
QQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQYYINRSISTAEAK
>Mature_531_residues
MEKRALIAVVLSILFFYGYTALFSPPPKETPKPVATATQSQPAQQVTAAPVPVAVPAQPQPAVAARDVSVDTPAYSVTFS
TQGGSIKRLDLKRYHETAGPGGKNVTLVSEDNPSNYTIGLRAPGFGLDQNAVFVPSADALTVGPGEKKQLSFTWVSPAGV
TVTKTYNFSGDGYGLEIQYQVTNSGSARVSSPVQTVQTYPLVPKVKESRFETFGPATFAQDKLFEDKVKDLESGAKTHAA
PLWSGFADKYFLSAVLAHEGSMAAATIRKTASGYLENTISSPELSLNPGEGRALTYRLFFGPKDIDVLKAQGNSLERAIN
LGWFAMLAKPLLHSLKFFHNYTGNYGIAIIIITVIIKVIFYPLTHSSYKSMKEMQKLQPKMQQLREKYKNDREAMNRAMM
ELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWITDLAAKDPYYVTPIIMGVTMVIQQKMTPSQMDPV
QQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQYYINRSISTAEAK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=505, Percent_Identity=36.039603960396, Blast_Score=294, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24662345, Length=298, Percent_Identity=23.8255033557047, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356443, Length=298, Percent_Identity=23.8255033557047, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_GEOSL (Q746Q2)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954506.1
- GeneID:   2686587
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3466
- NMPDR:   fig|243231.1.peg.3444
- TIGR:   GSU3466
- HOGENOM:   HBG507812
- OMA:   LHIMTES
- ProtClustDB:   CLSK829298
- BioCyc:   GSUL243231:GSU_3466-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 58700; Mature: 58700

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12884050)-; HASH(0x128bddf4)-; HASH(0x11d7c778)-; HASH(0x1263e568)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRALIAVVLSILFFYGYTALFSPPPKETPKPVATATQSQPAQQVTAAPVPVAVPAQPQ
CCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCC
PAVAARDVSVDTPAYSVTFSTQGGSIKRLDLKRYHETAGPGGKNVTLVSEDNPSNYTIGL
CCCEECCCCCCCCCEEEEEECCCCCEEEEHHHHHHHCCCCCCCEEEEEECCCCCCEEEEE
RAPGFGLDQNAVFVPSADALTVGPGEKKQLSFTWVSPAGVTVTKTYNFSGDGYGLEIQYQ
ECCCCCCCCCEEEECCCCEEEECCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEEEE
VTNSGSARVSSPVQTVQTYPLVPKVKESRFETFGPATFAQDKLFEDKVKDLESGAKTHAA
EECCCCCEECCCHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PLWSGFADKYFLSAVLAHEGSMAAATIRKTASGYLENTISSPELSLNPGEGRALTYRLFF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEE
GPKDIDVLKAQGNSLERAINLGWFAMLAKPLLHSLKFFHNYTGNYGIAIIIITVIIKVIF
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YPLTHSSYKSMKEMQKLQPKMQQLREKYKNDREAMNRAMMELYQTHKVNPVGGCLPMLVQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IPVFFALYKALMFSIELRHAPFMLWITDLAAKDPYYVTPIIMGVTMVIQQKMTPSQMDPV
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHH
QQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQYYINRSISTAEAK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MEKRALIAVVLSILFFYGYTALFSPPPKETPKPVATATQSQPAQQVTAAPVPVAVPAQPQ
CCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCC
PAVAARDVSVDTPAYSVTFSTQGGSIKRLDLKRYHETAGPGGKNVTLVSEDNPSNYTIGL
CCCEECCCCCCCCCEEEEEECCCCCEEEEHHHHHHHCCCCCCCEEEEEECCCCCCEEEEE
RAPGFGLDQNAVFVPSADALTVGPGEKKQLSFTWVSPAGVTVTKTYNFSGDGYGLEIQYQ
ECCCCCCCCCEEEECCCCEEEECCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEEEE
VTNSGSARVSSPVQTVQTYPLVPKVKESRFETFGPATFAQDKLFEDKVKDLESGAKTHAA
EECCCCCEECCCHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PLWSGFADKYFLSAVLAHEGSMAAATIRKTASGYLENTISSPELSLNPGEGRALTYRLFF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEE
GPKDIDVLKAQGNSLERAINLGWFAMLAKPLLHSLKFFHNYTGNYGIAIIIITVIIKVIF
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YPLTHSSYKSMKEMQKLQPKMQQLREKYKNDREAMNRAMMELYQTHKVNPVGGCLPMLVQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IPVFFALYKALMFSIELRHAPFMLWITDLAAKDPYYVTPIIMGVTMVIQQKMTPSQMDPV
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHH
QQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQYYINRSISTAEAK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA