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The map label for this gene is yfhR [C]

Identifier: 39998540

GI number: 39998540

Start: 3799051

End: 3799878

Strand: Reverse

Name: yfhR [C]

Synonym: GSU3451

Alternate gene names: 39998540

Gene position: 3799878-3799051 (Counterclockwise)

Preceding gene: 39998541

Following gene: 39998539

Centisome position: 99.63

GC content: 64.61

Gene sequence:

>828_bases
ATGGAGCATCCCCTCATCCGGATCGTCATCCTGGCCGTGCTCGCCTATGTGGGGTACGCACTGCTCTGTTTCCTGGTCCA
GCGCACCATCATCTATCCCGGCCGTTCCCTTTCCGTGGCCGGCCAGCCTCCCGATTTGCCCGACATCCATCCCCTCTGGC
TCACAACCCCATACGGCCACGTCGAATCCTGGTTTCTGCCGGCCACGGGGAGCGTTGCCGGAGACAGGCGTCCGGTGGTA
CTCTTTTTTCACGGCAACGGCGAGGTGATCGACGTTCTGCCGGACCAGGCCGAGGGGTTTCGCAGGATGGGGATGCACGT
CATGCTCGTGGAGTATCCGGGATACGGCCGTTCCGGCGGGTCGCCGTCAGAGGAGGGAATCACGGCTGCGGCCGTGGCCG
CCTATGATGAACTTGTGCGGAGGAGCGACACGGATTCCGGCCGCATGATCGCCTTCGGCAGGTCGCTCGGATGCGGGGCC
GCCTGTGCCCTGAGCCTCAGACGCCCGCTGGCGGCCCTTATCCTCCAGTCGCCGTTCACCTCGACCCGTCCCTTTGCCCG
GCAGATGCTCCTCCCCGGATTTCTGGCACGCGATGTCTTCGACAACCGTAAGGCCCTGGAATCCTACGGCGGAGCGGTCC
TCATCCTGCACGGCACGGAAGACGACATCATCCCCGTCGGCCACGGGCGCGAACTGGCCCGTACCGTCCGGCGCGGGTGC
CTGATAGAGCTTCGCTGCGGCCATAATGACTGCCCCCCCGACTGGCTGGAGTTCTGGCGGATCATTGAGGGATTTCTGGA
GCAGGAAGGGGTGTCGGGGAGAAAATGA

Upstream 100 bases:

>100_bases
CCCTGCGGACGCAGTTCCTGGCGGTGGCGCCGTCGCCAACCCGCCCGCCCGACGAGGAAACGCCGCCTCCCCACTACTGA
CAGCCATTCATGGGGGCCCC

Downstream 100 bases:

>100_bases
AAGGCCCGCCACTCTGCGGCGGGCCCCTGCTCATTCATATTTCCGAGTTCCCGTTTCACGGGATCTTCCGGCATCAACGG
CAGCCGGATTCGTACTGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MEHPLIRIVILAVLAYVGYALLCFLVQRTIIYPGRSLSVAGQPPDLPDIHPLWLTTPYGHVESWFLPATGSVAGDRRPVV
LFFHGNGEVIDVLPDQAEGFRRMGMHVMLVEYPGYGRSGGSPSEEGITAAAVAAYDELVRRSDTDSGRMIAFGRSLGCGA
ACALSLRRPLAALILQSPFTSTRPFARQMLLPGFLARDVFDNRKALESYGGAVLILHGTEDDIIPVGHGRELARTVRRGC
LIELRCGHNDCPPDWLEFWRIIEGFLEQEGVSGRK

Sequences:

>Translated_275_residues
MEHPLIRIVILAVLAYVGYALLCFLVQRTIIYPGRSLSVAGQPPDLPDIHPLWLTTPYGHVESWFLPATGSVAGDRRPVV
LFFHGNGEVIDVLPDQAEGFRRMGMHVMLVEYPGYGRSGGSPSEEGITAAAVAAYDELVRRSDTDSGRMIAFGRSLGCGA
ACALSLRRPLAALILQSPFTSTRPFARQMLLPGFLARDVFDNRKALESYGGAVLILHGTEDDIIPVGHGRELARTVRRGC
LIELRCGHNDCPPDWLEFWRIIEGFLEQEGVSGRK
>Mature_275_residues
MEHPLIRIVILAVLAYVGYALLCFLVQRTIIYPGRSLSVAGQPPDLPDIHPLWLTTPYGHVESWFLPATGSVAGDRRPVV
LFFHGNGEVIDVLPDQAEGFRRMGMHVMLVEYPGYGRSGGSPSEEGITAAAVAAYDELVRRSDTDSGRMIAFGRSLGCGA
ACALSLRRPLAALILQSPFTSTRPFARQMLLPGFLARDVFDNRKALESYGGAVLILHGTEDDIIPVGHGRELARTVRRGC
LIELRCGHNDCPPDWLEFWRIIEGFLEQEGVSGRK

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI109689718, Length=204, Percent_Identity=29.9019607843137, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI24308097, Length=204, Percent_Identity=29.9019607843137, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI194306564, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI71051600, Length=204, Percent_Identity=29.9019607843137, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194306562, Length=201, Percent_Identity=30.8457711442786, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI71051602, Length=201, Percent_Identity=29.8507462686567, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI32451492, Length=195, Percent_Identity=29.2307692307692, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI32528310, Length=195, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI151301175, Length=186, Percent_Identity=30.1075268817204, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI49355781, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI226510965, Length=193, Percent_Identity=27.4611398963731, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71988362, Length=158, Percent_Identity=31.0126582278481, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=185, Percent_Identity=30.2702702702703, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137566, Length=250, Percent_Identity=26.8, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362521, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362519, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571878, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 30210; Mature: 30210

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHPLIRIVILAVLAYVGYALLCFLVQRTIIYPGRSLSVAGQPPDLPDIHPLWLTTPYGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEECCCCC
VESWFLPATGSVAGDRRPVVLFFHGNGEVIDVLPDQAEGFRRMGMHVMLVEYPGYGRSGG
CCCEECCCCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHCCCEEEEEECCCCCCCCC
SPSEEGITAAAVAAYDELVRRSDTDSGRMIAFGRSLGCGAACALSLRRPLAALILQSPFT
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
STRPFARQMLLPGFLARDVFDNRKALESYGGAVLILHGTEDDIIPVGHGRELARTVRRGC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHHHHCC
LIELRCGHNDCPPDWLEFWRIIEGFLEQEGVSGRK
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEHPLIRIVILAVLAYVGYALLCFLVQRTIIYPGRSLSVAGQPPDLPDIHPLWLTTPYGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEECCCCC
VESWFLPATGSVAGDRRPVVLFFHGNGEVIDVLPDQAEGFRRMGMHVMLVEYPGYGRSGG
CCCEECCCCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHCCCEEEEEECCCCCCCCC
SPSEEGITAAAVAAYDELVRRSDTDSGRMIAFGRSLGCGAACALSLRRPLAALILQSPFT
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
STRPFARQMLLPGFLARDVFDNRKALESYGGAVLILHGTEDDIIPVGHGRELARTVRRGC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHHHHCC
LIELRCGHNDCPPDWLEFWRIIEGFLEQEGVSGRK
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]