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The map label for this gene is ackA-2 [H]

Identifier: 39998537

GI number: 39998537

Start: 3792646

End: 3793857

Strand: Reverse

Name: ackA-2 [H]

Synonym: GSU3448

Alternate gene names: 39998537

Gene position: 3793857-3792646 (Counterclockwise)

Preceding gene: 39998538

Following gene: 39998536

Centisome position: 99.47

GC content: 66.01

Gene sequence:

>1212_bases
ATGATTATCCTGATTCTCAATTGCCGGGGCTTTTCCATCCACTTCCAGCTCTTCGACTGGTCTACGCGGACCGTCCTCGC
CCGGGGGGACGTGGACCGGATCGAGCTGGGCGACTCGTTCATCTCTATGGAGGTACCGGGGCGGGACCCCTATCACCTGG
AGTCTGACTGCTCCAGTTTCGGTGCAGCCGTGGCCCTTATTCTCGCCACCCTGACCCACCCCCTGGAGGGTCCCCTCTCC
CGGGTCGAGCAGATCACCGCCGTGGGGCACCGGGTCGTTCACGGGGGGGAGCGGTTTACCTCCTCGGTTCCCATCGACGG
GAAGGTCATCGAGGCGGTCAGATCCGTGGAGGAACTGGCGCCGCTCCATATTCCCCCGAACCTGGCGGGGATCGAGGGAG
CCATGGCTACTCTGCCCGGCATTCCCCACGTGGCAGTCTTCGACACGGCATTCCACCAGGCAATGCCGCTCCATGCCTAC
CTCTACCCTCTCCCCTGGGAGTGGTACGAGCAGCACGGCGTGAGACGCTACGGCTTCCACGGCGCCTCCCATTGTCATGC
GGCGCGGCGGGGGGCGGCGCTCCTGGGGCGCGAGCCGGCCCTCTGTAATCTGGTCACCATCCACATCGGCAATGGGATTT
CCCTTTGCGCCGTGGAGGGAGGGTGCTCCATTGATACGAGCATGGGTCTCACGCCGCTGGAAGGGACCATGATGGGAACC
CGTTGCGGCTCCATCGACCCGGGCATTCCCCCGTTCATGATGCAGGAAGAACAGCTCTCGCCCCGTGATCTGGACCGGAT
TCTCAACCAGCGGAGCGGTGCCGCGGGCATCACCGGCCTCAAGCTGGACCGGTCGGCGTTTCTGGCCCGGGCCATCGCGG
GGGATGAGCGGTGCCTCCTGGCTCTGGAGATGGAGGCCTACCGACTCCGGAAGCACATCGGCGGCTACGCCGCGGCCCTC
GGCCGGCTCGACGCCGTGGTCTTCAGCGCGGCCTCGGGGGAGGGGGAATGGCTCGTGCGGGAAAAGGCCCTCGCCGACAT
GGCATGCTTCGGCATCCGGCTCGACCGGGAGCGGAACCGAACTGCCCGTTCCGTGGACCGGGAGGAGCGGGTCAGCGCCG
ATGACTCGCCTGTTGCGGTCTACGTGATTCCCACCGATGAGGAAATGGTTTACGCCGAGGAGGTGGCCGCGCTCCTGAAT
GGGCAGGGGTGA

Upstream 100 bases:

>100_bases
GCGCTGCCGAGGAAAAGATCCAGGAGGCCGTTGACACCTGTCCGGTCTCCTGCATCCATTGGGGGTAACAGCCCACACAT
CCCACGATACGGGAAGACAC

Downstream 100 bases:

>100_bases
CAACGACCGGGAATGGGGTAAACTGTTTTTCCTGTCGGATTCGATTCACCAAGGAGGCAGGCATGTCGCTGGAAGGCAAA
AAAGCTCCCGACTTCACCCT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MIILILNCRGFSIHFQLFDWSTRTVLARGDVDRIELGDSFISMEVPGRDPYHLESDCSSFGAAVALILATLTHPLEGPLS
RVEQITAVGHRVVHGGERFTSSVPIDGKVIEAVRSVEELAPLHIPPNLAGIEGAMATLPGIPHVAVFDTAFHQAMPLHAY
LYPLPWEWYEQHGVRRYGFHGASHCHAARRGAALLGREPALCNLVTIHIGNGISLCAVEGGCSIDTSMGLTPLEGTMMGT
RCGSIDPGIPPFMMQEEQLSPRDLDRILNQRSGAAGITGLKLDRSAFLARAIAGDERCLLALEMEAYRLRKHIGGYAAAL
GRLDAVVFSAASGEGEWLVREKALADMACFGIRLDRERNRTARSVDREERVSADDSPVAVYVIPTDEEMVYAEEVAALLN
GQG

Sequences:

>Translated_403_residues
MIILILNCRGFSIHFQLFDWSTRTVLARGDVDRIELGDSFISMEVPGRDPYHLESDCSSFGAAVALILATLTHPLEGPLS
RVEQITAVGHRVVHGGERFTSSVPIDGKVIEAVRSVEELAPLHIPPNLAGIEGAMATLPGIPHVAVFDTAFHQAMPLHAY
LYPLPWEWYEQHGVRRYGFHGASHCHAARRGAALLGREPALCNLVTIHIGNGISLCAVEGGCSIDTSMGLTPLEGTMMGT
RCGSIDPGIPPFMMQEEQLSPRDLDRILNQRSGAAGITGLKLDRSAFLARAIAGDERCLLALEMEAYRLRKHIGGYAAAL
GRLDAVVFSAASGEGEWLVREKALADMACFGIRLDRERNRTARSVDREERVSADDSPVAVYVIPTDEEMVYAEEVAALLN
GQG
>Mature_403_residues
MIILILNCRGFSIHFQLFDWSTRTVLARGDVDRIELGDSFISMEVPGRDPYHLESDCSSFGAAVALILATLTHPLEGPLS
RVEQITAVGHRVVHGGERFTSSVPIDGKVIEAVRSVEELAPLHIPPNLAGIEGAMATLPGIPHVAVFDTAFHQAMPLHAY
LYPLPWEWYEQHGVRRYGFHGASHCHAARRGAALLGREPALCNLVTIHIGNGISLCAVEGGCSIDTSMGLTPLEGTMMGT
RCGSIDPGIPPFMMQEEQLSPRDLDRILNQRSGAAGITGLKLDRSAFLARAIAGDERCLLALEMEAYRLRKHIGGYAAAL
GRLDAVVFSAASGEGEWLVREKALADMACFGIRLDRERNRTARSVDREERVSADDSPVAVYVIPTDEEMVYAEEVAALLN
GQG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=391, Percent_Identity=41.6879795396419, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=38.25, Blast_Score=268, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43759; Mature: 43759

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILILNCRGFSIHFQLFDWSTRTVLARGDVDRIELGDSFISMEVPGRDPYHLESDCSSF
CEEEEEECCCEEEEEEEEECCCEEEEECCCCCEEEECCCEEEEECCCCCCCCCHHHHHHH
GAAVALILATLTHPLEGPLSRVEQITAVGHRVVHGGERFTSSVPIDGKVIEAVRSVEELA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCHHHCCCCCCCHHHHHHHHHHHHHC
PLHIPPNLAGIEGAMATLPGIPHVAVFDTAFHQAMPLHAYLYPLPWEWYEQHGVRRYGFH
CCCCCCCCCCCCCHHHHCCCCCCEEEEHHHHHHCCCCEEEEECCCHHHHHHCCCEEECCC
GASHCHAARRGAALLGREPALCNLVTIHIGNGISLCAVEGGCSIDTSMGLTPLEGTMMGT
CCHHHHHHHCCCHHHCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEEC
RCGSIDPGIPPFMMQEEQLSPRDLDRILNQRSGAAGITGLKLDRSAFLARAIAGDERCLL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHCCCCEEEE
ALEMEAYRLRKHIGGYAAALGRLDAVVFSAASGEGEWLVREKALADMACFGIRLDRERNR
EEEHHHHHHHHHHCHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHHHCEEECCHHCH
TARSVDREERVSADDSPVAVYVIPTDEEMVYAEEVAALLNGQG
HHHHCCHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIILILNCRGFSIHFQLFDWSTRTVLARGDVDRIELGDSFISMEVPGRDPYHLESDCSSF
CEEEEEECCCEEEEEEEEECCCEEEEECCCCCEEEECCCEEEEECCCCCCCCCHHHHHHH
GAAVALILATLTHPLEGPLSRVEQITAVGHRVVHGGERFTSSVPIDGKVIEAVRSVEELA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCHHHCCCCCCCHHHHHHHHHHHHHC
PLHIPPNLAGIEGAMATLPGIPHVAVFDTAFHQAMPLHAYLYPLPWEWYEQHGVRRYGFH
CCCCCCCCCCCCCHHHHCCCCCCEEEEHHHHHHCCCCEEEEECCCHHHHHHCCCEEECCC
GASHCHAARRGAALLGREPALCNLVTIHIGNGISLCAVEGGCSIDTSMGLTPLEGTMMGT
CCHHHHHHHCCCHHHCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEEC
RCGSIDPGIPPFMMQEEQLSPRDLDRILNQRSGAAGITGLKLDRSAFLARAIAGDERCLL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHCCCCEEEE
ALEMEAYRLRKHIGGYAAALGRLDAVVFSAASGEGEWLVREKALADMACFGIRLDRERNR
EEEHHHHHHHHHHCHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHHHCEEECCHHCH
TARSVDREERVSADDSPVAVYVIPTDEEMVYAEEVAALLNGQG
HHHHCCHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA