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The map label for this gene is czcB [H]

Identifier: 39998488

GI number: 39998488

Start: 3738371

End: 3740119

Strand: Direct

Name: czcB [H]

Synonym: GSU3399

Alternate gene names: 39998488

Gene position: 3738371-3740119 (Clockwise)

Preceding gene: 39998487

Following gene: 39998489

Centisome position: 98.01

GC content: 67.87

Gene sequence:

>1749_bases
ATGATACGCACGATAACATACGGAATCCTGGCGCTGCTGGCCATGACGCTGCTGGTCGCCTGCAGCAAGGGAAACGGCAG
CCGGGAAGCCGGCGGCGAGGCCGGCCACGGGCCGGTGCAGATGACCGCCTGGTCGGACCGGACAGAGGTCTTTCTGGAGC
ATCCCGAGCTTGAACCGGGCAAAGGGGCGACGCTCCTCATCTATCTGACCCGCACGGCCGACTGGAAGCCCCTGGCGTCA
TCGGAGGTGCACCTGGTCATAACCCCGCCCGCGGGAACCCCTCTGACGGTGGCCGCCAAAGGGACCAAGCCGGGACTCTA
TCGGGCCGAAGCAACCTTCCCCGCCAAAGGCGCCTACCGGCTAACGGTGGTGATCGGCGGCTCCCAGGGGGAACAGATCG
AACTCCCCTCTCTCCTGGTTGGGGAAGGACATGACCACGGCGAGGGCGAGCACAAGGAGACGGCCGCGAGTGACCGGAAG
GAGGGAACTCCCCACGACCGCGACGACCACGGGGACCACGCCGCGGAGACGAAGCAGGGCGGAGGAAAAGAGCCCGCCCA
TGCCGAACATGACGACCACGATGAGCATGCCGGGCATGGCGGACACGACAGCCATGACGACCATGAGGGAGAGCAGGCGC
ACGACGAAACCGGCAAAGCCCATGCACACGCCGCCTCGGGAGCCGTCGGCGCCATCACCCTGACCAAGGAGCAGCAGTGG
GCCGTGGCCTTCGGCGTGGCCGAGCCGAGACGAATGGATATGGCCAGTGGCCTCACGGCGGTCGGCGAACTGGTGCCGGT
GGCCACGGCCGAGGCGGTAGTGGCCGCTCCCCTGGCAGGGGTCGTCTCCCCGACCCGCGCCCTTCCCTTCCCCGGCAAGC
GGGTGGCAAAGGGCGAGGTGATCGCGGTGATCGATCCTCCGGCAAGCCTTGGCGGAGGCATGACCCAGCTGGCCGCCGAC
CATGCCCAGGCCATGAGCCGTCTCACCCTGGCCCAGGCCGAGTACGATCGGGCCAAGCGGCTGGTGGAGGGAAAGATTGC
CGCCCGCAAGCGGCTTGAGGAGGCCGAGGCGTCCCTGGAGGCGGCCCGCGCCGTCGCAACACCCCTGGAGACTGCCATGA
AGAGCGTTCAGGGGGGGAGCGGCGGACGGATTACCGTGCGCGCGCCGGTCTCGGGCACCGTGGTCGAGGTCCCTGCCGTG
AACGGCAGCGGGGTAGCCCCTGGCCAGACCCTGGTCCGCATCGTGGATACCGGCCGGCTCTGGCTCCGGGTGAACCTCCC
GGCAACGGACCTGGGCAAGGTTGGACGCCCCGCGGCCGCTGGGACTACCTTCACCGTAACGGGACTGCCGGGAGAATTCC
ACACCAGCGGCCTCGTCTCCGACGGGACGGTGGTGGATCCCCAGACCCGGACTCTCCCGCTGGTCTTCGCCGTGGAAAAC
CGCAGCGGCAACCTCAAGGCAGGTATGTTCGCCCGGGTCACCATCCGGACCGGTACGGCCAAAGGTGTCCTGGCCGTACC
GAAAGAGGCCCTCTTCGAGGACGAAGGTCGCTGGTTCGCCTTCGTCCAGATCTCGGGAATCACCTTTGACCGCCGGGAGG
TGCAGATCGGAACCGAAGACCAGGGGATGATCCAGATCGTATCGGGGCTCGACGAGCATGACCGGCTGGTGGTGAAGGGG
GGCTACTACGTGAAGCTCGCTTCCCAGGGCGGGGCTACCGCCGACCCCCATGCCGGTCACGGCCACTAA

Upstream 100 bases:

>100_bases
ACCTGGCGGCCGTCCATGCCCGGCAGACGGCCCGTGCCCGCCTGGAGGCAGCCGTGGGCGCGCCCCTTGACGAACTGACA
ACAGGAGGTACCCAGTGAGC

Downstream 100 bases:

>100_bases
GGGGGCGCCGCCATGCTTGATCGTATAATCCGCTTATCCATAGAAAACCGCCTCATCGTGGTGGTCCTGTCGGCCCTCAT
CCTGGTGGTGGGGACCCTCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MIRTITYGILALLAMTLLVACSKGNGSREAGGEAGHGPVQMTAWSDRTEVFLEHPELEPGKGATLLIYLTRTADWKPLAS
SEVHLVITPPAGTPLTVAAKGTKPGLYRAEATFPAKGAYRLTVVIGGSQGEQIELPSLLVGEGHDHGEGEHKETAASDRK
EGTPHDRDDHGDHAAETKQGGGKEPAHAEHDDHDEHAGHGGHDSHDDHEGEQAHDETGKAHAHAASGAVGAITLTKEQQW
AVAFGVAEPRRMDMASGLTAVGELVPVATAEAVVAAPLAGVVSPTRALPFPGKRVAKGEVIAVIDPPASLGGGMTQLAAD
HAQAMSRLTLAQAEYDRAKRLVEGKIAARKRLEEAEASLEAARAVATPLETAMKSVQGGSGGRITVRAPVSGTVVEVPAV
NGSGVAPGQTLVRIVDTGRLWLRVNLPATDLGKVGRPAAAGTTFTVTGLPGEFHTSGLVSDGTVVDPQTRTLPLVFAVEN
RSGNLKAGMFARVTIRTGTAKGVLAVPKEALFEDEGRWFAFVQISGITFDRREVQIGTEDQGMIQIVSGLDEHDRLVVKG
GYYVKLASQGGATADPHAGHGH

Sequences:

>Translated_582_residues
MIRTITYGILALLAMTLLVACSKGNGSREAGGEAGHGPVQMTAWSDRTEVFLEHPELEPGKGATLLIYLTRTADWKPLAS
SEVHLVITPPAGTPLTVAAKGTKPGLYRAEATFPAKGAYRLTVVIGGSQGEQIELPSLLVGEGHDHGEGEHKETAASDRK
EGTPHDRDDHGDHAAETKQGGGKEPAHAEHDDHDEHAGHGGHDSHDDHEGEQAHDETGKAHAHAASGAVGAITLTKEQQW
AVAFGVAEPRRMDMASGLTAVGELVPVATAEAVVAAPLAGVVSPTRALPFPGKRVAKGEVIAVIDPPASLGGGMTQLAAD
HAQAMSRLTLAQAEYDRAKRLVEGKIAARKRLEEAEASLEAARAVATPLETAMKSVQGGSGGRITVRAPVSGTVVEVPAV
NGSGVAPGQTLVRIVDTGRLWLRVNLPATDLGKVGRPAAAGTTFTVTGLPGEFHTSGLVSDGTVVDPQTRTLPLVFAVEN
RSGNLKAGMFARVTIRTGTAKGVLAVPKEALFEDEGRWFAFVQISGITFDRREVQIGTEDQGMIQIVSGLDEHDRLVVKG
GYYVKLASQGGATADPHAGHGH
>Mature_582_residues
MIRTITYGILALLAMTLLVACSKGNGSREAGGEAGHGPVQMTAWSDRTEVFLEHPELEPGKGATLLIYLTRTADWKPLAS
SEVHLVITPPAGTPLTVAAKGTKPGLYRAEATFPAKGAYRLTVVIGGSQGEQIELPSLLVGEGHDHGEGEHKETAASDRK
EGTPHDRDDHGDHAAETKQGGGKEPAHAEHDDHDEHAGHGGHDSHDDHEGEQAHDETGKAHAHAASGAVGAITLTKEQQW
AVAFGVAEPRRMDMASGLTAVGELVPVATAEAVVAAPLAGVVSPTRALPFPGKRVAKGEVIAVIDPPASLGGGMTQLAAD
HAQAMSRLTLAQAEYDRAKRLVEGKIAARKRLEEAEASLEAARAVATPLETAMKSVQGGSGGRITVRAPVSGTVVEVPAV
NGSGVAPGQTLVRIVDTGRLWLRVNLPATDLGKVGRPAAAGTTFTVTGLPGEFHTSGLVSDGTVVDPQTRTLPLVFAVEN
RSGNLKAGMFARVTIRTGTAKGVLAVPKEALFEDEGRWFAFVQISGITFDRREVQIGTEDQGMIQIVSGLDEHDRLVVKG
GYYVKLASQGGATADPHAGHGH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 60709; Mature: 60709

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTITYGILALLAMTLLVACSKGNGSREAGGEAGHGPVQMTAWSDRTEVFLEHPELEPG
CCEEHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCC
KGATLLIYLTRTADWKPLASSEVHLVITPPAGTPLTVAAKGTKPGLYRAEATFPAKGAYR
CCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEECCCCCCCCCEE
LTVVIGGSQGEQIELPSLLVGEGHDHGEGEHKETAASDRKEGTPHDRDDHGDHAAETKQG
EEEEEECCCCCEEECCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCC
GGKEPAHAEHDDHDEHAGHGGHDSHDDHEGEQAHDETGKAHAHAASGAVGAITLTKEQQW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEEEECCCCE
AVAFGVAEPRRMDMASGLTAVGELVPVATAEAVVAAPLAGVVSPTRALPFPGKRVAKGEV
EEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCE
IAVIDPPASLGGGMTQLAADHAQAMSRLTLAQAEYDRAKRLVEGKIAARKRLEEAEASLE
EEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARAVATPLETAMKSVQGGSGGRITVRAPVSGTVVEVPAVNGSGVAPGQTLVRIVDTGRL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHEEEEEECCEE
WLRVNLPATDLGKVGRPAAAGTTFTVTGLPGEFHTSGLVSDGTVVDPQTRTLPLVFAVEN
EEEEECCCHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEC
RSGNLKAGMFARVTIRTGTAKGVLAVPKEALFEDEGRWFAFVQISGITFDRREVQIGTED
CCCCEEECEEEEEEEEECCCCCEEECCHHHHCCCCCCEEEEEEEECEEEECEEEEECCCC
QGMIQIVSGLDEHDRLVVKGGYYVKLASQGGATADPHAGHGH
CCHHHEECCCCCCCEEEEECCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRTITYGILALLAMTLLVACSKGNGSREAGGEAGHGPVQMTAWSDRTEVFLEHPELEPG
CCEEHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCC
KGATLLIYLTRTADWKPLASSEVHLVITPPAGTPLTVAAKGTKPGLYRAEATFPAKGAYR
CCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEECCCCCCCCCEE
LTVVIGGSQGEQIELPSLLVGEGHDHGEGEHKETAASDRKEGTPHDRDDHGDHAAETKQG
EEEEEECCCCCEEECCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCC
GGKEPAHAEHDDHDEHAGHGGHDSHDDHEGEQAHDETGKAHAHAASGAVGAITLTKEQQW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEEEECCCCE
AVAFGVAEPRRMDMASGLTAVGELVPVATAEAVVAAPLAGVVSPTRALPFPGKRVAKGEV
EEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCE
IAVIDPPASLGGGMTQLAADHAQAMSRLTLAQAEYDRAKRLVEGKIAARKRLEEAEASLE
EEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARAVATPLETAMKSVQGGSGGRITVRAPVSGTVVEVPAVNGSGVAPGQTLVRIVDTGRL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHEEEEEECCEE
WLRVNLPATDLGKVGRPAAAGTTFTVTGLPGEFHTSGLVSDGTVVDPQTRTLPLVFAVEN
EEEEECCCHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEC
RSGNLKAGMFARVTIRTGTAKGVLAVPKEALFEDEGRWFAFVQISGITFDRREVQIGTED
CCCCEEECEEEEEEEEECCCCCEEECCHHHHCCCCCCEEEEEEEECEEEECEEEEECCCC
QGMIQIVSGLDEHDRLVVKGGYYVKLASQGGATADPHAGHGH
CCHHHEECCCCCCCEEEEECCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]