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The map label for this gene is czcC [H]

Identifier: 39998487

GI number: 39998487

Start: 3737064

End: 3738368

Strand: Direct

Name: czcC [H]

Synonym: GSU3398

Alternate gene names: 39998487

Gene position: 3737064-3738368 (Clockwise)

Preceding gene: 39998486

Following gene: 39998488

Centisome position: 97.98

GC content: 67.2

Gene sequence:

>1305_bases
GTGAATCGAGCAGTTTCCCTGCCGGTGGCGGCCTTGTTGTTTCTTGCCGTCACCGGTGCGTCGGCGGGCAATGCCGGCGC
CGACACCAGAATCTTCACCCTTACCGAGGCCGTTGAGCACGCTCTCAGCAACAACGGTGAGCTCAAGGCGGCGCGGAGCG
GACACGAGGCCGCCCAAGCCGGCACCGTCCGGGCCGGGCTTTACCCCAATCCGGTCCTGGAGCTGGAAGGAGCCACCGGT
GCCCTCACCGGCAGCAGCAACGAAAACAGCATGGAACTGGCAATTTCCCAGGAAGTGCTGCTTGGCGGCAAGCGGGCCAA
ACGACTGGAAGCCGCGGAGCGGGACGTCGAGGCGGTCCGCTGGTGGTTGGCGGATCGGGAACGTCTCACTGCCCTGGAAG
TGAAGACGGCGTATGCCGATCTTCTGCTGGCCCAGCAACGGGTCGATCTGGCAAAGCAGGCCGCGGAGCTGGGCAGCCGC
CTGCTGACCCTGACGCAGGAGCGTTTCGCTGCGGGCGACATTCCTGAGCTGGAGGTCAACCTGGCCCGGGTCGAGGCGGC
GCGCAGCGACAGCGAGCGGATGGCGGCGGAACGGGAGATCGTGCCGGTCCGCTCTCGGCTCTCAACCCTCATGGGTCTTG
ACCCCGGCACTGAGGCGGCCGTTGTTGCGCCGCCCGACGAACAGCCCGTTACCGCCCTGGTTGCCGGCCTGGCAACCAAG
GCCCGGGAACACCGTCCCGACCTCAAGGCACTGACCGCCGAACAGGCCAGGGGCGAGGTAGAGGTGAGCCTTGCCCGGTC
CGAGGGGGTACCGAACCTGACAGTGGGACTCTTCGTGGCCCATGAGCGGAGCACCGACGCCATCGGCACCGACGAGGAAA
AAACCCGTGACACCATCGTGGGGGTAAGGCTCTCCCTGCCGCTCCCCCTCTTTGATCGCAACCAGGCCGGCATCCGCGAG
GCCGGTGCCCGCCGCGGGGGAACCGAGGCCCGGCTCATCGCCGCCCGCACCGCGCTGGAGCGGGAGGTGGCGGCGGAGTA
TGCCCGAATGGCCGCAGCGGAGGAGGTCCTCCGCCTCTACGCGAAGGATATCCTTCCACGGCTCAAGGAGAACCTCGCCC
TGGTTCAGGAGGCCTACGGACTGGGGGAAATAGACATTCTCGCGGTTATCGAGGAGCAGAAAAAATACGTGGCGGTCCAC
GGGTCATACCTGGCGGCCGTCCATGCCCGGCAGACGGCCCGTGCCCGCCTGGAGGCAGCCGTGGGCGCGCCCCTTGACGA
ACTGACAACAGGAGGTACCCAGTGA

Upstream 100 bases:

>100_bases
TGGAGGGAGACGTGCGTCTCCCTCCGGCGGTGGAGTTCGCCGTACAGCCCGTAATCCCTCACAGACTAGCCATTCAGATA
CACCACAAGGAGGTACTGCC

Downstream 100 bases:

>100_bases
GCATGATACGCACGATAACATACGGAATCCTGGCGCTGCTGGCCATGACGCTGCTGGTCGCCTGCAGCAAGGGAAACGGC
AGCCGGGAAGCCGGCGGCGA

Product: metal ion efflux outer membrane protein family protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNRAVSLPVAALLFLAVTGASAGNAGADTRIFTLTEAVEHALSNNGELKAARSGHEAAQAGTVRAGLYPNPVLELEGATG
ALTGSSNENSMELAISQEVLLGGKRAKRLEAAERDVEAVRWWLADRERLTALEVKTAYADLLLAQQRVDLAKQAAELGSR
LLTLTQERFAAGDIPELEVNLARVEAARSDSERMAAEREIVPVRSRLSTLMGLDPGTEAAVVAPPDEQPVTALVAGLATK
AREHRPDLKALTAEQARGEVEVSLARSEGVPNLTVGLFVAHERSTDAIGTDEEKTRDTIVGVRLSLPLPLFDRNQAGIRE
AGARRGGTEARLIAARTALEREVAAEYARMAAAEEVLRLYAKDILPRLKENLALVQEAYGLGEIDILAVIEEQKKYVAVH
GSYLAAVHARQTARARLEAAVGAPLDELTTGGTQ

Sequences:

>Translated_434_residues
MNRAVSLPVAALLFLAVTGASAGNAGADTRIFTLTEAVEHALSNNGELKAARSGHEAAQAGTVRAGLYPNPVLELEGATG
ALTGSSNENSMELAISQEVLLGGKRAKRLEAAERDVEAVRWWLADRERLTALEVKTAYADLLLAQQRVDLAKQAAELGSR
LLTLTQERFAAGDIPELEVNLARVEAARSDSERMAAEREIVPVRSRLSTLMGLDPGTEAAVVAPPDEQPVTALVAGLATK
AREHRPDLKALTAEQARGEVEVSLARSEGVPNLTVGLFVAHERSTDAIGTDEEKTRDTIVGVRLSLPLPLFDRNQAGIRE
AGARRGGTEARLIAARTALEREVAAEYARMAAAEEVLRLYAKDILPRLKENLALVQEAYGLGEIDILAVIEEQKKYVAVH
GSYLAAVHARQTARARLEAAVGAPLDELTTGGTQ
>Mature_434_residues
MNRAVSLPVAALLFLAVTGASAGNAGADTRIFTLTEAVEHALSNNGELKAARSGHEAAQAGTVRAGLYPNPVLELEGATG
ALTGSSNENSMELAISQEVLLGGKRAKRLEAAERDVEAVRWWLADRERLTALEVKTAYADLLLAQQRVDLAKQAAELGSR
LLTLTQERFAAGDIPELEVNLARVEAARSDSERMAAEREIVPVRSRLSTLMGLDPGTEAAVVAPPDEQPVTALVAGLATK
AREHRPDLKALTAEQARGEVEVSLARSEGVPNLTVGLFVAHERSTDAIGTDEEKTRDTIVGVRLSLPLPLFDRNQAGIRE
AGARRGGTEARLIAARTALEREVAAEYARMAAAEEVLRLYAKDILPRLKENLALVQEAYGLGEIDILAVIEEQKKYVAVH
GSYLAAVHARQTARARLEAAVGAPLDELTTGGTQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 46312; Mature: 46312

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAVSLPVAALLFLAVTGASAGNAGADTRIFTLTEAVEHALSNNGELKAARSGHEAAQA
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEECCCCCHHHHC
GTVRAGLYPNPVLELEGATGALTGSSNENSMELAISQEVLLGGKRAKRLEAAERDVEAVR
CCEEECCCCCCCEEECCCCEEEECCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHH
WWLADRERLTALEVKTAYADLLLAQQRVDLAKQAAELGSRLLTLTQERFAAGDIPELEVN
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LARVEAARSDSERMAAEREIVPVRSRLSTLMGLDPGTEAAVVAPPDEQPVTALVAGLATK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHH
AREHRPDLKALTAEQARGEVEVSLARSEGVPNLTVGLFVAHERSTDAIGTDEEKTRDTIV
HHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHEE
GVRLSLPLPLFDRNQAGIREAGARRGGTEARLIAARTALEREVAAEYARMAAAEEVLRLY
EEEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKDILPRLKENLALVQEAYGLGEIDILAVIEEQKKYVAVHGSYLAAVHARQTARARLEAA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCEEEEECHHHHHHHHHHHHHHHHHHH
VGAPLDELTTGGTQ
HCCCHHHHCCCCCC
>Mature Secondary Structure
MNRAVSLPVAALLFLAVTGASAGNAGADTRIFTLTEAVEHALSNNGELKAARSGHEAAQA
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEECCCCCHHHHC
GTVRAGLYPNPVLELEGATGALTGSSNENSMELAISQEVLLGGKRAKRLEAAERDVEAVR
CCEEECCCCCCCEEECCCCEEEECCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHH
WWLADRERLTALEVKTAYADLLLAQQRVDLAKQAAELGSRLLTLTQERFAAGDIPELEVN
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LARVEAARSDSERMAAEREIVPVRSRLSTLMGLDPGTEAAVVAPPDEQPVTALVAGLATK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHH
AREHRPDLKALTAEQARGEVEVSLARSEGVPNLTVGLFVAHERSTDAIGTDEEKTRDTIV
HHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHEE
GVRLSLPLPLFDRNQAGIREAGARRGGTEARLIAARTALEREVAAEYARMAAAEEVLRLY
EEEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKDILPRLKENLALVQEAYGLGEIDILAVIEEQKKYVAVHGSYLAAVHARQTARARLEAA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCEEEEECHHHHHHHHHHHHHHHHHHH
VGAPLDELTTGGTQ
HCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]