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The map label for this gene is adrA [H]

Identifier: 39998445

GI number: 39998445

Start: 3685627

End: 3687228

Strand: Direct

Name: adrA [H]

Synonym: GSU3356

Alternate gene names: 39998445

Gene position: 3685627-3687228 (Clockwise)

Preceding gene: 39998444

Following gene: 39998446

Centisome position: 96.63

GC content: 62.86

Gene sequence:

>1602_bases
ATGAGACGAGCAAGCCTGAAAACCAAAACAGCCCTCTTTGTGCTCCTCGTCTTCTTTACCACGGCTCCCACTGCGGTCTA
CCTGACACTTGAGTTCTTCGGAAGGTCGCTGCGGGACGTGGTGAATACCCACCAGGCGACCCTGCTGGCTCGAATCGGCG
CTGAAATTGACGAAAAGCTCCAGGGCAGCCATGACGCCCTCATAAATGTCGCTCGCATGGCCACTGCCGACGACGTGACG
TCCCCCGAGAGCGCCCGGCGCTTTCTTCATCGCTATCCCCTGCTGGCGGCATTCTTCGACAACGGCGTGTTCGTGTTCAC
GCCCGCCGGAATCTTGATGGCCGAGACTAATCAGGGGTTGCAGCGAACCGGCCTCGACTTCTCCGCCCGCGAGTACATCC
GGCAGACCAGGATCTCGGAGCGCCCCTACATCTCGAGGCCCTTCGTGTCGAGCCAGCCCCACCACCATCCCACCGTCATG
TTCACTGCCCCGGTCTTTACGCCGAACGGAACCCTCGTTGCCATTCTCGGGGGGAGCATGGATCTGCTCAAGGGGAATTT
CATCGGCTCCCTTGCCTCAACCCGCATCGGCAAGGGAGGTCACTTTTACCTGTTTGCCGACGACGGCGTCCTGATCATGC
ATCCCCAACGGGAAAATATCCTGCAGCAGAACGTCAGCTCGGAGGTTCTGAACCACGCATCCTCCGTGCCCCGAGGAGGC
GTCATCTCGGCCGAAACGGTCAGCGACGGCACCCCCATGCTGAGTACCCTGAAAAAGCTGAGCCAGACGACATGGACCCT
GGCGGCCGACCTGCCGAAGGACGAGGCCTATGCGCCGCTCCGCATGGCGGAGCGTTCGGCATGGGCGGCCATCATCCCGT
GGGGACTCTTGAGCGTCGCGGCCATCTGGCTTCTCATGCGCCGGCTGACACTGCCGATCCTCGCGCTGGAGTGCCAGATT
CGCGAGGCCGAGGACAGCGGTGCCCACCGCAACGTGCTGATCCGTTCGGGGGACGAGATCGAACGGGTGGCCGAGGCATT
CAACGGCCTCGTCAACCGGCTCATCGAGAAGGAAGACCGGCTCGTCCACCTCTCCAACCACGACTCCCTGACCGGGCTCT
ACAACCGCCTCTTTTTCGAGGCGGAGATGCAGCGGATCGACCGGGGACGGCATTTCCCCGTAAGCATGGTGATGGTTGAC
GTGGACAATCTGAAAACGGTCAACGACACCTTCGGCCACACGGCGGGCGATGCTCTCATCATCAAGGCGGCCCAGGCCCT
GCGGGCGGCATTCCGGTCCGAAGACGTGGTGGCGCGGGTCGGCGGCGACGAGTTCGCCGTCATCATGGAGGGATCCGACC
ACGAAACGGCGCTGGAGGCACTGGAACGTGTCCGGGAAACCGTAGCGCTGCTCAACTCCGACGGAGATTCTCCCGAACTA
GCCCTCTCGCTGGGCACCGCCACGGCCACGGCACCGCTCACCCTCGGACAAAGCTGGCGCCTGGCGGACCAGCGCATGTA
TGCCGACAAGGCGCGACGCAAGGCATCAAAGATAATCGGAAGCGGCTCCGCTTCCCGTGATTCGGCCGTTTCGGCCTCCT
GA

Upstream 100 bases:

>100_bases
CAGGCTGGAGTCGCTTCGGATGCAAAAAAGCTCAAGCAATGAAACCACGGTGACGAAATGATATACTACTGGTTACTACT
TTTTCCCACGGCGGCGCGAC

Downstream 100 bases:

>100_bases
ACGCGGTCGCCGCATCCTCCGGAGCGGGATACCGCGAACAAGGTAGGGCTACAGCCTTACCCGGAGAACACCGGATGAAT
CCCTTGGCCGCCAGCCACTT

Product: GGDEF domain/HAMP domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MRRASLKTKTALFVLLVFFTTAPTAVYLTLEFFGRSLRDVVNTHQATLLARIGAEIDEKLQGSHDALINVARMATADDVT
SPESARRFLHRYPLLAAFFDNGVFVFTPAGILMAETNQGLQRTGLDFSAREYIRQTRISERPYISRPFVSSQPHHHPTVM
FTAPVFTPNGTLVAILGGSMDLLKGNFIGSLASTRIGKGGHFYLFADDGVLIMHPQRENILQQNVSSEVLNHASSVPRGG
VISAETVSDGTPMLSTLKKLSQTTWTLAADLPKDEAYAPLRMAERSAWAAIIPWGLLSVAAIWLLMRRLTLPILALECQI
REAEDSGAHRNVLIRSGDEIERVAEAFNGLVNRLIEKEDRLVHLSNHDSLTGLYNRLFFEAEMQRIDRGRHFPVSMVMVD
VDNLKTVNDTFGHTAGDALIIKAAQALRAAFRSEDVVARVGGDEFAVIMEGSDHETALEALERVRETVALLNSDGDSPEL
ALSLGTATATAPLTLGQSWRLADQRMYADKARRKASKIIGSGSASRDSAVSAS

Sequences:

>Translated_533_residues
MRRASLKTKTALFVLLVFFTTAPTAVYLTLEFFGRSLRDVVNTHQATLLARIGAEIDEKLQGSHDALINVARMATADDVT
SPESARRFLHRYPLLAAFFDNGVFVFTPAGILMAETNQGLQRTGLDFSAREYIRQTRISERPYISRPFVSSQPHHHPTVM
FTAPVFTPNGTLVAILGGSMDLLKGNFIGSLASTRIGKGGHFYLFADDGVLIMHPQRENILQQNVSSEVLNHASSVPRGG
VISAETVSDGTPMLSTLKKLSQTTWTLAADLPKDEAYAPLRMAERSAWAAIIPWGLLSVAAIWLLMRRLTLPILALECQI
REAEDSGAHRNVLIRSGDEIERVAEAFNGLVNRLIEKEDRLVHLSNHDSLTGLYNRLFFEAEMQRIDRGRHFPVSMVMVD
VDNLKTVNDTFGHTAGDALIIKAAQALRAAFRSEDVVARVGGDEFAVIMEGSDHETALEALERVRETVALLNSDGDSPEL
ALSLGTATATAPLTLGQSWRLADQRMYADKARRKASKIIGSGSASRDSAVSAS
>Mature_533_residues
MRRASLKTKTALFVLLVFFTTAPTAVYLTLEFFGRSLRDVVNTHQATLLARIGAEIDEKLQGSHDALINVARMATADDVT
SPESARRFLHRYPLLAAFFDNGVFVFTPAGILMAETNQGLQRTGLDFSAREYIRQTRISERPYISRPFVSSQPHHHPTVM
FTAPVFTPNGTLVAILGGSMDLLKGNFIGSLASTRIGKGGHFYLFADDGVLIMHPQRENILQQNVSSEVLNHASSVPRGG
VISAETVSDGTPMLSTLKKLSQTTWTLAADLPKDEAYAPLRMAERSAWAAIIPWGLLSVAAIWLLMRRLTLPILALECQI
REAEDSGAHRNVLIRSGDEIERVAEAFNGLVNRLIEKEDRLVHLSNHDSLTGLYNRLFFEAEMQRIDRGRHFPVSMVMVD
VDNLKTVNDTFGHTAGDALIIKAAQALRAAFRSEDVVARVGGDEFAVIMEGSDHETALEALERVRETVALLNSDGDSPEL
ALSLGTATATAPLTLGQSWRLADQRMYADKARRKASKIIGSGSASRDSAVSAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=34.6820809248555, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082007, Length=152, Percent_Identity=36.8421052631579, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=156, Percent_Identity=34.6153846153846, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=36.2573099415205, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87081974, Length=151, Percent_Identity=32.4503311258278, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=158, Percent_Identity=30.379746835443, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788381, Length=101, Percent_Identity=38.6138613861386, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081977, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788085, Length=187, Percent_Identity=26.7379679144385, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787056, Length=150, Percent_Identity=31.3333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787541, Length=137, Percent_Identity=35.036496350365, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787816, Length=150, Percent_Identity=30, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 58409; Mature: 58409

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRASLKTKTALFVLLVFFTTAPTAVYLTLEFFGRSLRDVVNTHQATLLARIGAEIDEKL
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QGSHDALINVARMATADDVTSPESARRFLHRYPLLAAFFDNGVFVFTPAGILMAETNQGL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHEEHHCCCEEEEECCCEEEECCCCCH
QRTGLDFSAREYIRQTRISERPYISRPFVSSQPHHHPTVMFTAPVFTPNGTLVAILGGSM
HHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCH
DLLKGNFIGSLASTRIGKGGHFYLFADDGVLIMHPQRENILQQNVSSEVLNHASSVPRGG
HHHCCCHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
VISAETVSDGTPMLSTLKKLSQTTWTLAADLPKDEAYAPLRMAERSAWAAIIPWGLLSVA
EEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHCCCCEEHHHHHHHHHH
AIWLLMRRLTLPILALECQIREAEDSGAHRNVLIRSGDEIERVAEAFNGLVNRLIEKEDR
HHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
LVHLSNHDSLTGLYNRLFFEAEMQRIDRGRHFPVSMVMVDVDNLKTVNDTFGHTAGDALI
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHCCCCCCCHHH
IKAAQALRAAFRSEDVVARVGGDEFAVIMEGSDHETALEALERVRETVALLNSDGDSPEL
HHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
ALSLGTATATAPLTLGQSWRLADQRMYADKARRKASKIIGSGSASRDSAVSAS
EEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRASLKTKTALFVLLVFFTTAPTAVYLTLEFFGRSLRDVVNTHQATLLARIGAEIDEKL
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QGSHDALINVARMATADDVTSPESARRFLHRYPLLAAFFDNGVFVFTPAGILMAETNQGL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHEEHHCCCEEEEECCCEEEECCCCCH
QRTGLDFSAREYIRQTRISERPYISRPFVSSQPHHHPTVMFTAPVFTPNGTLVAILGGSM
HHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCH
DLLKGNFIGSLASTRIGKGGHFYLFADDGVLIMHPQRENILQQNVSSEVLNHASSVPRGG
HHHCCCHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
VISAETVSDGTPMLSTLKKLSQTTWTLAADLPKDEAYAPLRMAERSAWAAIIPWGLLSVA
EEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHCCCCEEHHHHHHHHHH
AIWLLMRRLTLPILALECQIREAEDSGAHRNVLIRSGDEIERVAEAFNGLVNRLIEKEDR
HHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
LVHLSNHDSLTGLYNRLFFEAEMQRIDRGRHFPVSMVMVDVDNLKTVNDTFGHTAGDALI
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHCCCCCCCHHH
IKAAQALRAAFRSEDVVARVGGDEFAVIMEGSDHETALEALERVRETVALLNSDGDSPEL
HHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
ALSLGTATATAPLTLGQSWRLADQRMYADKARRKASKIIGSGSASRDSAVSAS
EEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]