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The map label for this gene is kup3

Identifier: 39998435

GI number: 39998435

Start: 3675042

End: 3676874

Strand: Reverse

Name: kup3

Synonym: GSU3346

Alternate gene names: 39998435

Gene position: 3676874-3675042 (Counterclockwise)

Preceding gene: 39998442

Following gene: 308513343

Centisome position: 96.4

GC content: 60.39

Gene sequence:

>1833_bases
TTGTCTTGGGCTGATATGGAACATCACAAGCACGATACATTCTTGGGGGGCATCGTCAAGGCCCTGGGCCTCGTCTTCGG
CGACATCGGCACGAGTCCCATTTATACCCTGACGGTTATCTTTACCCTCACGCAACCCACGATCGATAACGTCTACGGCA
TTCTTTCCCTCATTTTCTGGACCATGACGATCCTCGTTTCCGCCGAGTATGCCTGGCTCGCCATGAGCCTGGGGCGCAAG
GGGCAGGGGGGGGAGATCGTCCTGCGGGAAATAATCATGAAGCTGGTCAAGGCCGGGCGTCTGGTGGCCTTTGCCGGCTT
TCTCTCCTTTGTGGGGGTGTCGCTGCTGCTGGGCGACGCGGTCATCACCCCGGCCATCAGTATCCTCTCCGCCGTGGAGG
GTCTGCTTCTCATCCCCGGTTTGGAAGGGCTGTCTACAGGGGCTCTGGTTGCCATTGCCGCGGCCATCGCCATCGGCCTT
TTCTCGGTCCAGCACAAGGGGACCGACCGGGTGGCCAGCGCGTTCGGGCCGATCATGGCCCTCTGGTTCGGAACCCTCGC
CGTTACCGGTGCCGTCTCCGCCTTTTCCATGCCGCAGATCGTTGAGGCGATCAATCCCTTGCACGGCATCGCCTTTTTCC
GCGACAACGGACTGGCCGGCTACTTCGTCCTCTCCGAGGTAATACTCTGCGCCACCGGCGGAGAGGCCCTCTACGCGGAC
ATGGGGCATCTGGGGAAAAGGCCGATCGTCCGGGCGTGGCACTTCGTGTTCGTAGCCCTCTACCTTAACTACCTGGGCCA
GGGGGTGTTCGCCATTGCCCATCCCGATGCGAAAAACCTCCTCTTCGGCATGGTACGGAGCCAGGCGCCGGCCCTCTACA
TCCCCTTCCTGATCCTCACCATCATGGCCACCATCATCGCCTCCCAGGCCATCATCAGCGGGGTCTTCTCCATCGTCTAC
CAGGGGATCACCACGCGGCTCCTCCCGCTGATGCGGGTCGACTACACGTCACGTCAGATCAAGTCACAGATCTACCTCGG
CGCCGTCAACTGGTCGCTTATGGTAGCGGTCATCTTCATCATGCTGGTTTTCCGCAAGTCCGAGAACCTGGCCGCAGCCT
ACGGTATGGCGGTGACGGGCTCCATGACCATCACCGGCATCATGATGATCATCGTTTTCTCCCACACCACCAAGAAGTGG
CGTGCCCTGGTGGCCCTGGTGGTGACTCTCATCGCAGCCGCCTACCACGTGTCCACTTTCTCCAAGCTGCCCCACGGCGC
CTACTGGTCCATCATCCTGGCGTCAATCCCCTTTGTGACCATCATCATCTGGACCCGAGGCCAGCGCACCCTCTACCGCG
CCCTGAAGCCCCTGGACCTGGAGACGTTCCTCATCTCCTACGAGCAGATCTACGCCAAGGGCCCCATCCGCGGGACCGGG
CTCTTCTTCACCCGGGAGACCGACGTGGTCCCCCCCTACGTGGTCCACTGCATCATCCGGAGCAACATCATCTATGAGCG
CAATGTGTTCATTTCCCTGATGATCAGCGACGAGCCCCTGGGCGTGGAAACTGAGCTGATCAGGGGAATCGGGCCGGGTC
TCGACGCATTCCGGATTGAGGCGGGGTACATGGAGATGGTGGATATCGAACGGCTGCTGAAAGAGAATGGCATTCAGGAG
AAGGTCATCTTCTACGGCGTCGAGGACATCAGTACCCGCAATCCGTTCTGGCGCTTCTTCTCGGTCCTCAAAAAACTCAC
TCCCAACTTCGTCCAGTTCCACAAACTGCCGGCCAGCCGACTCCAGGGCGTGGTGACGCGGGTGGAGATGTAG

Upstream 100 bases:

>100_bases
AAGGGCGAAGCTCCCCTCCCCGGGCCGGGAATTGTGTTGAGTTGGCCGGAGCGAAGTGATATAAGGTGCCGGTTGTTGAG
TTCTGATTTTTCGACAGTTC

Downstream 100 bases:

>100_bases
CCTCCCTACTTCACGCACCGCTCCCGCGCCGCCTTCACCATCGCCAGCACCCGCTCGTCCGCTCCTTCTTTCGGTGCGGA
CACCATGCGGACATAGGCCG

Product: potassium uptake protein, Kup system

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSWADMEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFWTMTILVSAEYAWLAMSLGRK
GQGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDAVITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGL
FSVQHKGTDRVASAFGPIMALWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYAD
MGHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILTIMATIIASQAIISGVFSIVY
QGITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFIMLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKW
RALVALVVTLIAAAYHVSTFSKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTG
LFFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIEAGYMEMVDIERLLKENGIQE
KVIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASRLQGVVTRVEM

Sequences:

>Translated_610_residues
MSWADMEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFWTMTILVSAEYAWLAMSLGRK
GQGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDAVITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGL
FSVQHKGTDRVASAFGPIMALWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYAD
MGHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILTIMATIIASQAIISGVFSIVY
QGITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFIMLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKW
RALVALVVTLIAAAYHVSTFSKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTG
LFFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIEAGYMEMVDIERLLKENGIQE
KVIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASRLQGVVTRVEM
>Mature_609_residues
SWADMEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFWTMTILVSAEYAWLAMSLGRKG
QGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDAVITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGLF
SVQHKGTDRVASAFGPIMALWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYADM
GHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILTIMATIIASQAIISGVFSIVYQ
GITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFIMLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKWR
ALVALVVTLIAAAYHVSTFSKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTGL
FFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIEAGYMEMVDIERLLKENGIQEK
VIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASRLQGVVTRVEM

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=557, Percent_Identity=34.6499102333932, Blast_Score=286, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP3_GEOSL (Q747C1)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954386.1
- GeneID:   2687636
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3346
- NMPDR:   fig|243231.1.peg.3324
- TIGR:   GSU3346
- HOGENOM:   HBG351154
- OMA:   HGAYWSI
- ProtClustDB:   CLSK900490
- BioCyc:   GSUL243231:GSU_3346-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 67008; Mature: 66877

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11f9ddb8)-; HASH(0x11a17f38)-; HASH(0x11f75408)-; HASH(0x11a6aba8)-; HASH(0x11df7428)-; HASH(0x121461e8)-; HASH(0x117aab90)-; HASH(0x11b500e4)-; HASH(0x12225ee4)-; HASH(0x11f5fa44)-; HASH(0x11ced5d0)-; HASH(0x119a47c0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWADMEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFW
CCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
TMTILVSAEYAWLAMSLGRKGQGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGLFSVQHKGTDRVASAFGPIMA
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYAD
HHHHHHHHHHHHHHCCHHHHHHHHCHHHHEEEEECCCCCHHHHHHHHHHHCCCCCHHHHH
MGHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILT
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHH
IMATIIASQAIISGVFSIVYQGITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCHHHHHHHHHH
MLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKWRALVALVVTLIAAAYHVSTF
HHHHHCCCCHHHHHCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTG
HHCCCCHHHHHHHHHCCEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
LFFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIE
EEEECCCCCCCHHHHHHHHHCCEEEECCEEEEEEECCCCCCCHHHHHHHCCCCCCCEEEC
AGYMEMVDIERLLKENGIQEKVIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASR
CCHHHHHHHHHHHHHCCCCCEEEEEECHHCCCCCHHHHHHHHHHHHCCHHHHHHCCCHHH
LQGVVTRVEM
HHHHHHHCCH
>Mature Secondary Structure 
SWADMEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFW
CCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
TMTILVSAEYAWLAMSLGRKGQGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGLFSVQHKGTDRVASAFGPIMA
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYAD
HHHHHHHHHHHHHHCCHHHHHHHHCHHHHEEEEECCCCCHHHHHHHHHHHCCCCCHHHHH
MGHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILT
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHH
IMATIIASQAIISGVFSIVYQGITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCHHHHHHHHHH
MLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKWRALVALVVTLIAAAYHVSTF
HHHHHCCCCHHHHHCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTG
HHCCCCHHHHHHHHHCCEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
LFFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIE
EEEECCCCCCCHHHHHHHHHCCEEEECCEEEEEEECCCCCCCHHHHHHHCCCCCCCEEEC
AGYMEMVDIERLLKENGIQEKVIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASR
CCHHHHHHHHHHHHHCCCCCEEEEEECHHCCCCCHHHHHHHHHHHHCCHHHHHHCCCHHH
LQGVVTRVEM
HHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA