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The map label for this gene is cheA-3 [H]

Identifier: 39998289

GI number: 39998289

Start: 3506196

End: 3507881

Strand: Direct

Name: cheA-3 [H]

Synonym: GSU3199

Alternate gene names: 39998289

Gene position: 3506196-3507881 (Clockwise)

Preceding gene: 39998288

Following gene: 39998290

Centisome position: 91.93

GC content: 66.13

Gene sequence:

>1686_bases
ATGGACATGTCCCAGTACCGGGACCTCTTCGTTGCCGAGGCCCGGGAACACCTGGAGCGCCTGGGCGAAGAGGTACTGGC
CCTGGAAAAGGACCCGGCCAACGGCGAACGCCTCGACTCGCTCTTCCGCACCGCCCACTCCATCAAAGGCATGGCGGGCT
CCATGGGATATGACGGCATAGCCGACCTTTCCCACCGCATGGAAGACCTGATGGACCGCGTCCGCAAGGGCCGGATTCCC
TTTGGCCGGGACATCGCCGACCTGCTGCTGGCCTGCGCGGACCAGTTGGGACGAATGGTGGAAGACGTGACCGGCGGCGG
GAACGGCTCCCTCGACGCGACAGACCTCTGCGCCAGACTCGCCCTGGTTGCCGGGCAGGAGGCCGCAGCCCCGGCGGCTC
CAGCCGATGCAGAGACATCCCCCTCCCCGCAGCCATCCGACCAGCCGGAACCGGCACGTCGCGACGAAAGCGACGGGGCG
CGAACCGTCCGGATCCGGTCAGAGCTTCTTGACCGATTTGTCAACATAACCGGCGAACTGGTCACCGGCAAGAACCGGAT
CATGGAACTGGCGGCGGGACTCGAATCCGAACCACTGCGGGATGCGGCGGCCGAACTGTCGAAACTGGTCCGCGACCTGC
AGCGCGAGGTCATGTCGGCCAGAATGATGCCCTTCGGCACCATCTGCGACCGTTTCCCCCGCATGGTGCGGGATCTGGCT
CGCCGTAGCGGGAAAGAGGCGACGCTGGCCATCGACGGCAAGGATCAGGAACTGGATCGCGGCATTCTGGAAATTCTCCC
CGACCCTCTGCTCCATGCCCTGCGCAATGCCGTCGATCACGGCATCGAGTCGCCGGAGGAACGGAGTGCGGCCGGAAAGG
GAGCGGGGGGTCGGATCGTCCTGTCGGTTCGCAGGGAAAAAGACCATCTGGACGTGACAGTGACGGATGACGGGCGGGGC
ATGGATCCGGCAGCTCTCGTCAACGCCGCCCTTGCCAAGGGAATCATCACCCCGGAAGAGGCGGCGACGCTCAGCCGGCA
GGAGGCGTTGATGCTCGTCTGCAGGCCGGGCTTTTCCACGGCCAGGAGCGTCACCGAGGTATCCGGAAGAGGGGTGGGGA
TGGATGCGGTGCAAGCCGCTGTAAGTCGGGCGGGTGGCAGCCTGTCCATCCAGTCCGAGCGAGGCCGGGGAAGCAGGATC
ACCCTTCGGCTCCCCCTGAGCGTGGCGATCATCCAGGTGCTCCTGGTGGGCTGCGGCCCGCTGACCATGGCGGTTCCCGT
CAACGCCGTCCGCCGGACCGTCGAGCTGGACCGGCGGCTCCAGCGCATCGAAGATGGGCGGGCTGTTTTTGATCTGGGCG
GGGAAACCCTCCCGCTGGTTGACCTGGGCCTGCTCGTGGGGACCGGCCCGACTGCCGGCGGGGATTTCTCGCCCGTTCTG
ACGGCCGACGTTGCAGGACGCACAATGGGGTTTGCCGTGGACCGTTTTTTCGGACAGGCAGAGGTATTCACCAAGCCGCT
CGGCACGCCGCTCAACCGTGCCAGGGGGCTTGCGGGAGGAGCTATACTGGGAGACGGTCGGGTCATCTTCATCCTCGACC
TCCCCAATCTTGTCGACGGGGCCACCAGCCGGCGCCGCGTTTTCATGCACCCTGACGGTGCGCACAAAGGGGGAACGACC
GCATGA

Upstream 100 bases:

>100_bases
TGGACAAAGCCCGGAGCGTGGGCGCGAAAGACTTCATCCTCAAACCGTTCAATCCGGAGCGGGTCAAGGATGTGATGAAG
CAGGTGACCGAGGGCTAGAC

Downstream 100 bases:

>100_bases
AATTCGATGCATTGACCGAGGAGCACCTGGACGCCCTCAAGGAAGTAAGCAACATCGGTGTGGCTCACGCAGCCACTGCC
CTTTCCCAGCTGATCGGCAA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MDMSQYRDLFVAEAREHLERLGEEVLALEKDPANGERLDSLFRTAHSIKGMAGSMGYDGIADLSHRMEDLMDRVRKGRIP
FGRDIADLLLACADQLGRMVEDVTGGGNGSLDATDLCARLALVAGQEAAAPAAPADAETSPSPQPSDQPEPARRDESDGA
RTVRIRSELLDRFVNITGELVTGKNRIMELAAGLESEPLRDAAAELSKLVRDLQREVMSARMMPFGTICDRFPRMVRDLA
RRSGKEATLAIDGKDQELDRGILEILPDPLLHALRNAVDHGIESPEERSAAGKGAGGRIVLSVRREKDHLDVTVTDDGRG
MDPAALVNAALAKGIITPEEAATLSRQEALMLVCRPGFSTARSVTEVSGRGVGMDAVQAAVSRAGGSLSIQSERGRGSRI
TLRLPLSVAIIQVLLVGCGPLTMAVPVNAVRRTVELDRRLQRIEDGRAVFDLGGETLPLVDLGLLVGTGPTAGGDFSPVL
TADVAGRTMGFAVDRFFGQAEVFTKPLGTPLNRARGLAGGAILGDGRVIFILDLPNLVDGATSRRRVFMHPDGAHKGGTT
A

Sequences:

>Translated_561_residues
MDMSQYRDLFVAEAREHLERLGEEVLALEKDPANGERLDSLFRTAHSIKGMAGSMGYDGIADLSHRMEDLMDRVRKGRIP
FGRDIADLLLACADQLGRMVEDVTGGGNGSLDATDLCARLALVAGQEAAAPAAPADAETSPSPQPSDQPEPARRDESDGA
RTVRIRSELLDRFVNITGELVTGKNRIMELAAGLESEPLRDAAAELSKLVRDLQREVMSARMMPFGTICDRFPRMVRDLA
RRSGKEATLAIDGKDQELDRGILEILPDPLLHALRNAVDHGIESPEERSAAGKGAGGRIVLSVRREKDHLDVTVTDDGRG
MDPAALVNAALAKGIITPEEAATLSRQEALMLVCRPGFSTARSVTEVSGRGVGMDAVQAAVSRAGGSLSIQSERGRGSRI
TLRLPLSVAIIQVLLVGCGPLTMAVPVNAVRRTVELDRRLQRIEDGRAVFDLGGETLPLVDLGLLVGTGPTAGGDFSPVL
TADVAGRTMGFAVDRFFGQAEVFTKPLGTPLNRARGLAGGAILGDGRVIFILDLPNLVDGATSRRRVFMHPDGAHKGGTT
A
>Mature_561_residues
MDMSQYRDLFVAEAREHLERLGEEVLALEKDPANGERLDSLFRTAHSIKGMAGSMGYDGIADLSHRMEDLMDRVRKGRIP
FGRDIADLLLACADQLGRMVEDVTGGGNGSLDATDLCARLALVAGQEAAAPAAPADAETSPSPQPSDQPEPARRDESDGA
RTVRIRSELLDRFVNITGELVTGKNRIMELAAGLESEPLRDAAAELSKLVRDLQREVMSARMMPFGTICDRFPRMVRDLA
RRSGKEATLAIDGKDQELDRGILEILPDPLLHALRNAVDHGIESPEERSAAGKGAGGRIVLSVRREKDHLDVTVTDDGRG
MDPAALVNAALAKGIITPEEAATLSRQEALMLVCRPGFSTARSVTEVSGRGVGMDAVQAAVSRAGGSLSIQSERGRGSRI
TLRLPLSVAIIQVLLVGCGPLTMAVPVNAVRRTVELDRRLQRIEDGRAVFDLGGETLPLVDLGLLVGTGPTAGGDFSPVL
TADVAGRTMGFAVDRFFGQAEVFTKPLGTPLNRARGLAGGAILGDGRVIFILDLPNLVDGATSRRRVFMHPDGAHKGGTT
A

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=398, Percent_Identity=35.427135678392, Blast_Score=244, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59816; Mature: 59816

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMSQYRDLFVAEAREHLERLGEEVLALEKDPANGERLDSLFRTAHSIKGMAGSMGYDGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHH
ADLSHRMEDLMDRVRKGRIPFGRDIADLLLACADQLGRMVEDVTGGGNGSLDATDLCARL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALVAGQEAAAPAAPADAETSPSPQPSDQPEPARRDESDGARTVRIRSELLDRFVNITGEL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
VTGKNRIMELAAGLESEPLRDAAAELSKLVRDLQREVMSARMMPFGTICDRFPRMVRDLA
ECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RRSGKEATLAIDGKDQELDRGILEILPDPLLHALRNAVDHGIESPEERSAAGKGAGGRIV
HHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEE
LSVRREKDHLDVTVTDDGRGMDPAALVNAALAKGIITPEEAATLSRQEALMLVCRPGFST
EEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCHH
ARSVTEVSGRGVGMDAVQAAVSRAGGSLSIQSERGRGSRITLRLPLSVAIIQVLLVGCGP
HHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCC
LTMAVPVNAVRRTVELDRRLQRIEDGRAVFDLGGETLPLVDLGLLVGTGPTAGGDFSPVL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEECHHHHHHHEECCCCCCCCCCCEE
TADVAGRTMGFAVDRFFGQAEVFTKPLGTPLNRARGLAGGAILGDGRVIFILDLPNLVDG
EHHHCCCHHHHHHHHHHCHHHHHHCCCCCHHHHHCCCCCCEEEECCEEEEEEECCHHHCC
ATSRRRVFMHPDGAHKGGTTA
CCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDMSQYRDLFVAEAREHLERLGEEVLALEKDPANGERLDSLFRTAHSIKGMAGSMGYDGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHH
ADLSHRMEDLMDRVRKGRIPFGRDIADLLLACADQLGRMVEDVTGGGNGSLDATDLCARL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALVAGQEAAAPAAPADAETSPSPQPSDQPEPARRDESDGARTVRIRSELLDRFVNITGEL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
VTGKNRIMELAAGLESEPLRDAAAELSKLVRDLQREVMSARMMPFGTICDRFPRMVRDLA
ECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RRSGKEATLAIDGKDQELDRGILEILPDPLLHALRNAVDHGIESPEERSAAGKGAGGRIV
HHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEE
LSVRREKDHLDVTVTDDGRGMDPAALVNAALAKGIITPEEAATLSRQEALMLVCRPGFST
EEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCHH
ARSVTEVSGRGVGMDAVQAAVSRAGGSLSIQSERGRGSRITLRLPLSVAIIQVLLVGCGP
HHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCC
LTMAVPVNAVRRTVELDRRLQRIEDGRAVFDLGGETLPLVDLGLLVGTGPTAGGDFSPVL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEECHHHHHHHEECCCCCCCCCCCEE
TADVAGRTMGFAVDRFFGQAEVFTKPLGTPLNRARGLAGGAILGDGRVIFILDLPNLVDG
EHHHCCCHHHHHHHHHHCHHHHHHCCCCCHHHHHCCCCCCEEEECCEEEEEEECCHHHCC
ATSRRRVFMHPDGAHKGGTTA
CCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]