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The map label for this gene is bioH [H]

Identifier: 39997722

GI number: 39997722

Start: 2899593

End: 2900414

Strand: Reverse

Name: bioH [H]

Synonym: GSU2628

Alternate gene names: 39997722

Gene position: 2900414-2899593 (Counterclockwise)

Preceding gene: 39997723

Following gene: 39997721

Centisome position: 76.04

GC content: 66.06

Gene sequence:

>822_bases
ATGCCGTTTCTTCAAATAGACCATAACCTGACGATTCATTATGACGACGAGGGGGACGGCTTCCCCCTGGTGCTCGTCCA
CGGCTGGGCCATGGAAGGGGGCGTCTGGGCCTTCCAGCGGCCGCTGGCATCCTCGTTCCGGGTAATCACCGTGGATCTCA
GGGGCCACGGCCGGTCCACGGCGCCGGGTGACGGGTACGGCCTCGCCGATTTCGCGGCAGATATCGTGGTGCTGTTTGAC
GAGCTTGGCCTGGAACGGGCCGCGATTGTCGGCTGGTCCCTCGGTGCCCAGGCGGCCCTGGAGGCGGCACCGCTGCTGGG
AGACCGCCTTGCCGCGCTCGTGCTCGTGGGGGCGACCCCCCGGTTCTCGGCAACGGATGGATGGCTCCACGGTCTCCCCG
CCACCGAATGTCGGGGGCTGGGGCTGCGTCTGCGGCGCACGTTCGACGCGGCGCTTGACGGCTTTTTCCACAGCATGTTC
GCAGAGGGGGAACTCTCTGACGAATCCGAACGGCTCATCGGGCAAGAGATCACCGCATCGTGGCGCCGTCCCGCAGCCAC
GGCCGCTCAGGCTGCCCTCGTCACCCTGGCGGAAAGCGACCAGCGCCACCTCCTGGAGAAAATTCGAGTGCCCACCCTGG
TTATTCACGGCGACCGGGACGCCATCTGTCCCCTCGAAGCCGGCGCCCATCTGGCGGATCATCTTCCCCTGGGCCGATTC
CTGTTGTTCGCCGGAACCGGCCATGCCCCCTTTCTTTCCCGTCCCCGGGAATTCAACAGCGAGGTGACACGCTTTCTGCG
CGAGGTGGCCGGAGATGATTGA

Upstream 100 bases:

>100_bases
GTACTCTCATGGCGACCCACGACGAGTCCGACCTGGAGCGCGCCGTGGCCGCCATGGCGCGGATCGGCAAAGAACTGGGC
ATTGTGTGACCCGAGGTATC

Downstream 100 bases:

>100_bases
TCGCCGCAAGGTCCGCAACGCCTTCCACCGGGGGGCCGCCGACTATGATGCCTATGCCGCGGTGCAGAAGCGGGTCATGG
AGCGGATACTTTCCCTCCTC

Product: non-heme peroxidase

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPFLQIDHNLTIHYDDEGDGFPLVLVHGWAMEGGVWAFQRPLASSFRVITVDLRGHGRSTAPGDGYGLADFAADIVVLFD
ELGLERAAIVGWSLGAQAALEAAPLLGDRLAALVLVGATPRFSATDGWLHGLPATECRGLGLRLRRTFDAALDGFFHSMF
AEGELSDESERLIGQEITASWRRPAATAAQAALVTLAESDQRHLLEKIRVPTLVIHGDRDAICPLEAGAHLADHLPLGRF
LLFAGTGHAPFLSRPREFNSEVTRFLREVAGDD

Sequences:

>Translated_273_residues
MPFLQIDHNLTIHYDDEGDGFPLVLVHGWAMEGGVWAFQRPLASSFRVITVDLRGHGRSTAPGDGYGLADFAADIVVLFD
ELGLERAAIVGWSLGAQAALEAAPLLGDRLAALVLVGATPRFSATDGWLHGLPATECRGLGLRLRRTFDAALDGFFHSMF
AEGELSDESERLIGQEITASWRRPAATAAQAALVTLAESDQRHLLEKIRVPTLVIHGDRDAICPLEAGAHLADHLPLGRF
LLFAGTGHAPFLSRPREFNSEVTRFLREVAGDD
>Mature_272_residues
PFLQIDHNLTIHYDDEGDGFPLVLVHGWAMEGGVWAFQRPLASSFRVITVDLRGHGRSTAPGDGYGLADFAADIVVLFDE
LGLERAAIVGWSLGAQAALEAAPLLGDRLAALVLVGATPRFSATDGWLHGLPATECRGLGLRLRRTFDAALDGFFHSMFA
EGELSDESERLIGQEITASWRRPAATAAQAALVTLAESDQRHLLEKIRVPTLVIHGDRDAICPLEAGAHLADHLPLGRFL
LFAGTGHAPFLSRPREFNSEVTRFLREVAGDD

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

Organism=Escherichia coli, GI1789817, Length=250, Percent_Identity=30.4, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 29565; Mature: 29434

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLQIDHNLTIHYDDEGDGFPLVLVHGWAMEGGVWAFQRPLASSFRVITVDLRGHGRST
CCCEEECCEEEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHCCCEEEEEEEEECCCCCC
APGDGYGLADFAADIVVLFDELGLERAAIVGWSLGAQAALEAAPLLGDRLAALVLVGATP
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEECCCC
RFSATDGWLHGLPATECRGLGLRLRRTFDAALDGFFHSMFAEGELSDESERLIGQEITAS
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
WRRPAATAAQAALVTLAESDQRHLLEKIRVPTLVIHGDRDAICPLEAGAHLADHLPLGRF
HCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCE
LLFAGTGHAPFLSRPREFNSEVTRFLREVAGDD
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFLQIDHNLTIHYDDEGDGFPLVLVHGWAMEGGVWAFQRPLASSFRVITVDLRGHGRST
CCEEECCEEEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHCCCEEEEEEEEECCCCCC
APGDGYGLADFAADIVVLFDELGLERAAIVGWSLGAQAALEAAPLLGDRLAALVLVGATP
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEECCCC
RFSATDGWLHGLPATECRGLGLRLRRTFDAALDGFFHSMFAEGELSDESERLIGQEITAS
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
WRRPAATAAQAALVTLAESDQRHLLEKIRVPTLVIHGDRDAICPLEAGAHLADHLPLGRF
HCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCE
LLFAGTGHAPFLSRPREFNSEVTRFLREVAGDD
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA