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The map label for this gene is aroA

Identifier: 39997700

GI number: 39997700

Start: 2873688

End: 2874977

Strand: Reverse

Name: aroA

Synonym: GSU2606

Alternate gene names: 39997700

Gene position: 2874977-2873688 (Counterclockwise)

Preceding gene: 39997701

Following gene: 39997699

Centisome position: 75.38

GC content: 69.77

Gene sequence:

>1290_bases
GTGGTAAGCCTGAGTTCACACCCCGCCCGTGCGCTGCGCGGCGAAATCGCGGTGCCGGGGGACAAATCGATCTCCCACCG
CTCCATCATGCTCGGCTCCATCGCCCGCGGCGTGACCACGGTGAGCGGCTTTCTCCGGGGCGAGGACAATATCGCCACCC
TCGACGCCTTCCGGGCCATGGGGGTGCAGGTCCACGACGACGGCGAGACCCTGCGGATCGAGGGGAAAGGGCTCCACGGC
CTGACCGAGGCCGAGGACGTCATCGACTGCGGCAACTCCGGCACGTCCATCCGGCTCCTGACGGGGCTCATGGCGGCCCA
GCGCTTCTACACGGTCCTAACCGGCGACCGCTACCTGCGGCGCAGGCCCATGCGGCGGGTGGTGGAACCCCTTTCGCGCA
TGGGGGCCTGCATCCACGGCCGCGACAACGGAGAAAAGGCGCCCCTTGCCATCGTTGGCCGGCCCCTGACCGGCATCGCC
TACGATTCGCCGGTGGCCAGCGCCCAGGTGAAATCGGCCCTCATGCTGGCCGGTCTCTACGCCGACGGCGCTACCCGCGT
CACCGAGCCCCATCTCTCGCGGGATCACTCGGAGCGGATGTTCCGCCACTTCGGCGCCCGGTTGGAGACCGACGCCGCCG
GGGTCACCGTGTACGGCGGGCACGAGCTGGACGGCCGCGACATCGTGGTGCCGGGCGACATCTCCTCGGCGGCCTTTTTC
CTGGTTGCCGCCCTGATCGTCCCCGGCTCCGAGCTGCTCATCCGGGGGGTGGGCGTGAACCCGACCCGCACGGGCATCCT
CGACATTCTCGCCGCCATGGGGGGCTCGGTGGAGCTGCTCGACCAGCGCGAAGTCTCCGGCGAGCCGGTGGCCGACCTGC
TGGTCCGGTCATCTGCCCTCAAGGGGATCGAGATCGGAGGGGACGTGGTGCCCCGGGCCATCGACGAATTCCCGGTCATC
TGCGTGGCCGCCGCCCTGGCCGAAGGAACCACCGTCATCCGCGACGCGCGTGAGCTGCGGGTCAAGGAAACGGACCGCAT
CGCCGCCATGGCCGCCAACCTGCGCGCGGCGGGTGCCACTATCACCGAGACGGCGGACGGCATGATCATCGAGGGGACCG
GCCGGCTGAACGGCGTCACCGTGGAGAGCTTCGGCGACCACCGGATCGCCATGTCCATGCTCGTGGCGGGGCTTGCCGCC
TCGGGGGCCATCACCGTAAGCGACACCGAGTGCATCGCCACCTCGTTCCCCACCTTCACCGCGCTCCTGGACAAGGTGGC
GGTACGGTGA

Upstream 100 bases:

>100_bases
CGGTCCCTGGTGGCCGCGGGGGACGCTGAAGGTCTCGAACGGTTCTTCCGGGATTCCAAGGAGTCCCGTGACGCCATACT
CTAGCTGCAAAGGAGTGTCC

Downstream 100 bases:

>100_bases
GCGCGGCGGGGCGCAGGGGGCTCATCGTCGCCATCGACGGACCGTCGGGCGCCGGGAAGAGCACCATAACCAAGCTCCTG
GCGGACCGGCTCGGCTACAT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MVSLSSHPARALRGEIAVPGDKSISHRSIMLGSIARGVTTVSGFLRGEDNIATLDAFRAMGVQVHDDGETLRIEGKGLHG
LTEAEDVIDCGNSGTSIRLLTGLMAAQRFYTVLTGDRYLRRRPMRRVVEPLSRMGACIHGRDNGEKAPLAIVGRPLTGIA
YDSPVASAQVKSALMLAGLYADGATRVTEPHLSRDHSERMFRHFGARLETDAAGVTVYGGHELDGRDIVVPGDISSAAFF
LVAALIVPGSELLIRGVGVNPTRTGILDILAAMGGSVELLDQREVSGEPVADLLVRSSALKGIEIGGDVVPRAIDEFPVI
CVAAALAEGTTVIRDARELRVKETDRIAAMAANLRAAGATITETADGMIIEGTGRLNGVTVESFGDHRIAMSMLVAGLAA
SGAITVSDTECIATSFPTFTALLDKVAVR

Sequences:

>Translated_429_residues
MVSLSSHPARALRGEIAVPGDKSISHRSIMLGSIARGVTTVSGFLRGEDNIATLDAFRAMGVQVHDDGETLRIEGKGLHG
LTEAEDVIDCGNSGTSIRLLTGLMAAQRFYTVLTGDRYLRRRPMRRVVEPLSRMGACIHGRDNGEKAPLAIVGRPLTGIA
YDSPVASAQVKSALMLAGLYADGATRVTEPHLSRDHSERMFRHFGARLETDAAGVTVYGGHELDGRDIVVPGDISSAAFF
LVAALIVPGSELLIRGVGVNPTRTGILDILAAMGGSVELLDQREVSGEPVADLLVRSSALKGIEIGGDVVPRAIDEFPVI
CVAAALAEGTTVIRDARELRVKETDRIAAMAANLRAAGATITETADGMIIEGTGRLNGVTVESFGDHRIAMSMLVAGLAA
SGAITVSDTECIATSFPTFTALLDKVAVR
>Mature_429_residues
MVSLSSHPARALRGEIAVPGDKSISHRSIMLGSIARGVTTVSGFLRGEDNIATLDAFRAMGVQVHDDGETLRIEGKGLHG
LTEAEDVIDCGNSGTSIRLLTGLMAAQRFYTVLTGDRYLRRRPMRRVVEPLSRMGACIHGRDNGEKAPLAIVGRPLTGIA
YDSPVASAQVKSALMLAGLYADGATRVTEPHLSRDHSERMFRHFGARLETDAAGVTVYGGHELDGRDIVVPGDISSAAFF
LVAALIVPGSELLIRGVGVNPTRTGILDILAAMGGSVELLDQREVSGEPVADLLVRSSALKGIEIGGDVVPRAIDEFPVI
CVAAALAEGTTVIRDARELRVKETDRIAAMAANLRAAGATITETADGMIIEGTGRLNGVTVESFGDHRIAMSMLVAGLAA
SGAITVSDTECIATSFPTFTALLDKVAVR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=441, Percent_Identity=30.3854875283447, Blast_Score=148, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6320332, Length=424, Percent_Identity=28.5377358490566, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_GEOSL (Q749Y6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953651.1
- HSSP:   Q9S400
- ProteinModelPortal:   Q749Y6
- SMR:   Q749Y6
- GeneID:   2686305
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2606
- NMPDR:   fig|243231.1.peg.2589
- TIGR:   GSU2606
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   GSUL243231:GSU_2606-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45115; Mature: 45115

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLSSHPARALRGEIAVPGDKSISHRSIMLGSIARGVTTVSGFLRGEDNIATLDAFRAM
CCCCCCCCHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GVQVHDDGETLRIEGKGLHGLTEAEDVIDCGNSGTSIRLLTGLMAAQRFYTVLTGDRYLR
CCEEECCCCEEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
RRPMRRVVEPLSRMGACIHGRDNGEKAPLAIVGRPLTGIAYDSPVASAQVKSALMLAGLY
HHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
ADGATRVTEPHLSRDHSERMFRHFGARLETDAAGVTVYGGHELDGRDIVVPGDISSAAFF
CCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCEEEECCCCCCCCEEEECCCCCHHHHH
LVAALIVPGSELLIRGVGVNPTRTGILDILAAMGGSVELLDQREVSGEPVADLLVRSSAL
HHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHC
KGIEIGGDVVPRAIDEFPVICVAAALAEGTTVIRDARELRVKETDRIAAMAANLRAAGAT
CCEECCCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
ITETADGMIIEGTGRLNGVTVESFGDHRIAMSMLVAGLAASGAITVSDTECIATSFPTFT
EEECCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHH
ALLDKVAVR
HHHHHHHCC
>Mature Secondary Structure
MVSLSSHPARALRGEIAVPGDKSISHRSIMLGSIARGVTTVSGFLRGEDNIATLDAFRAM
CCCCCCCCHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GVQVHDDGETLRIEGKGLHGLTEAEDVIDCGNSGTSIRLLTGLMAAQRFYTVLTGDRYLR
CCEEECCCCEEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
RRPMRRVVEPLSRMGACIHGRDNGEKAPLAIVGRPLTGIAYDSPVASAQVKSALMLAGLY
HHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
ADGATRVTEPHLSRDHSERMFRHFGARLETDAAGVTVYGGHELDGRDIVVPGDISSAAFF
CCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCEEEECCCCCCCCEEEECCCCCHHHHH
LVAALIVPGSELLIRGVGVNPTRTGILDILAAMGGSVELLDQREVSGEPVADLLVRSSAL
HHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHC
KGIEIGGDVVPRAIDEFPVICVAAALAEGTTVIRDARELRVKETDRIAAMAANLRAAGAT
CCEECCCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
ITETADGMIIEGTGRLNGVTVESFGDHRIAMSMLVAGLAASGAITVSDTECIATSFPTFT
EEECCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHH
ALLDKVAVR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA