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The map label for this gene is iscR [H]

Identifier: 39997666

GI number: 39997666

Start: 2833441

End: 2833878

Strand: Reverse

Name: iscR [H]

Synonym: GSU2571

Alternate gene names: 39997666

Gene position: 2833878-2833441 (Counterclockwise)

Preceding gene: 39997667

Following gene: 39997665

Centisome position: 74.3

GC content: 67.35

Gene sequence:

>438_bases
ATGAGACTGTCGACGCGCGCCCAGTATGCGGTGCGGGCCATGGTCGATCTGTCGCTCCACTCGGAGGGGAAGCCCGTGGC
CCTGCGGGATATCGCCCAGCGGGAGGACATCCCGCTCAACTACCTGGAGCAACTCTTCAACCGCCTGCGTCGCGGCAGCA
TCGTGGAGAGCGTGCGCGGGCCCGGCGGGGGCTACCTGCTGGCCCGGGAGAGCTCGGCCATCCTGGTGGGCGAAATCGTG
GCCACGGTGGAAGAACCGCTGACGCCGGTCTCCTGCATGGACAAGGGGAAGGGGCGCTGTACCCGCACTGCGGCATGCAC
CACCCATTCGGTCTGGGAGATGCTCGGCGAGCGGATCAGGACGTTCCTGGATTCCATCACCCTGGAGGACTTGGTGCGGG
ACGCCCGCCGACGGCCCGGCGAGAGTGAGGATCAATGA

Upstream 100 bases:

>100_bases
CTGTCTCTTCGAACAGATCCGGGAGCTGGAGCGCAAGTACGGCGAACTGGCCGCCGAGCACGAGGCGCTGAAGCGCCGCC
TGGATGGGGGGAATTAGTCC

Downstream 100 bases:

>100_bases
GTGAAGCCCCCGCGGGCACTGTCCCGCTGATCTATCTGGACCACAACGCGACGACGCCGACGCACCCCTTGGTGGTGGAG
GCGTTGTTGCCGTTTCTGGG

Product: Rrf2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRLSTRAQYAVRAMVDLSLHSEGKPVALRDIAQREDIPLNYLEQLFNRLRRGSIVESVRGPGGGYLLARESSAILVGEIV
ATVEEPLTPVSCMDKGKGRCTRTAACTTHSVWEMLGERIRTFLDSITLEDLVRDARRRPGESEDQ

Sequences:

>Translated_145_residues
MRLSTRAQYAVRAMVDLSLHSEGKPVALRDIAQREDIPLNYLEQLFNRLRRGSIVESVRGPGGGYLLARESSAILVGEIV
ATVEEPLTPVSCMDKGKGRCTRTAACTTHSVWEMLGERIRTFLDSITLEDLVRDARRRPGESEDQ
>Mature_145_residues
MRLSTRAQYAVRAMVDLSLHSEGKPVALRDIAQREDIPLNYLEQLFNRLRRGSIVESVRGPGGGYLLARESSAILVGEIV
ATVEEPLTPVSCMDKGKGRCTRTAACTTHSVWEMLGERIRTFLDSITLEDLVRDARRRPGESEDQ

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=48.5074626865672, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1790621, Length=134, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16186; Mature: 16186

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSTRAQYAVRAMVDLSLHSEGKPVALRDIAQREDIPLNYLEQLFNRLRRGSIVESVRG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHCC
PGGGYLLARESSAILVGEIVATVEEPLTPVSCMDKGKGRCTRTAACTTHSVWEMLGERIR
CCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TFLDSITLEDLVRDARRRPGESEDQ
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLSTRAQYAVRAMVDLSLHSEGKPVALRDIAQREDIPLNYLEQLFNRLRRGSIVESVRG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHCC
PGGGYLLARESSAILVGEIVATVEEPLTPVSCMDKGKGRCTRTAACTTHSVWEMLGERIR
CCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TFLDSITLEDLVRDARRRPGESEDQ
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA