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The map label for this gene is speA [H]

Identifier: 39997632

GI number: 39997632

Start: 2799433

End: 2801340

Strand: Reverse

Name: speA [H]

Synonym: GSU2537

Alternate gene names: 39997632

Gene position: 2801340-2799433 (Counterclockwise)

Preceding gene: 39997633

Following gene: 39997631

Centisome position: 73.45

GC content: 59.38

Gene sequence:

>1908_bases
ATGGAACGCTGGTCGATTAACGAATCTGCGAAGATCTACAACCTGCCCAACTGGGGCGCCGACCTCTTCTCCATCAACAA
GAAGGGGAACGTCTGCGTGCACCCGTCACCCACGTCCAAGCATTCCATCGACCTGCGTGCCCTGGTGGACGATCTGATCA
AGCGCAAGATCAAGCCCCCCATCCTGCTCCGGTTCATGGACGTGCTCCAGGGGCGGATCGCATCCATCAACCGAGTCTTC
AAGAACGCCATCGACGAGAACGACTACCCGGCCACCTACCAGACCTTCTACCCCATCAAGGTGAACCAGCAGCGCCAGGT
GGTGGAGGCCATCGCCAAGTTCGGCAAGCGCTACAATATCGGCCTGGAAGTGGGCTCCAAGCCGGAGCTGGTGATCGGCA
TCTCCTTCGCCACCGGCAACGGCATCCCCATCATCTGCAACGGTTACAAGGACACCGAGTATATCGAGACGGTCCTCTAC
GCCACCAAGATCGGCTACGACATCACCATCGTGGTGGAGAAGATGTTCGAGCTGGAGAAGATCATTGCCCTGTCGAAAAA
GACCGGCATCAAGCCCAAGCTGGGCATCCGGGTGAAGCTTTCCTCCAAGGGGACCGGCAAGTGGGCCACTTCCGGCGGTG
AGGACGCCAAGTTCGGCCTCCGGATGTCGGAGATCATCGCCGCTATCGGGCTCCTGGAGCAAAATGACCTCCTGGACCGG
GTGAAGCTCCTCCACTTCCACATCGGCAGCCAGATCACCAAGATCGACAAGATCAAGAGCGCCCTGATCGAGGGAACCCG
TATCTACGCCGAGATGCGCAAGCTGGGGGTCGGCATCCGGTACGTGGACATCGGCGGCGGCCTGGGGGTCGACTACGACG
GGTCCAAGTCGAGCTACTTCTCCAGCGTCAACTACTCCATCGAGGAGTACGCCAACGACGTCATCTACCAGATCAAGAAC
ATCTGTGAGGACGCCGGCGTCGAATGCCCCAACATCATCTCCGAATCGGGGCGGGCCACGGCGGCCCACTACTCGGTGCT
CGTGACCAATCTCCTCAACACCAACACGTCCAATGCCATGCCCGACTTCGAGGAGACCCTCAACGGCACGGAAAAGCTGG
CCCCAACGGTCAAGAAGCTGGTGGACATCTACAAGAGCATCGACCGCTATTCTCTGCGGGAGGACTACCACGATACGGTC
CAGCTCATCCAAGAGGCGGTGAGCCTCTTCAACCTGGGCTACCTGACCCTTAACGAGCGGGCCATGGCCGAGTGGCTCCA
CGGTAAGATCCTGCGCAAGATCAACGGCATCGTGGAAAAGATCAAGCCGATCCCCGAGGAGCTCCAGAATTTCCAGCTGA
GCCTGCGGCAGACCTATTTCGCCAATTTCTCGCTGTTCCAGTCGATTCCCGACTCTTGGGCCATCGACCAGCTCTTTCCC
ATCGTGCCGATCCAGCGGCTCAACCAGAAGCCCGACGTGATGGCCTCCATCGCCGACATCACCTGCGATTCGGACGGGGA
GATCACCAGCTTCGTGGGCGAGAACGGCCGGACCAAGTACCTGCCGCTTCACAAGATGCGCAAGGACGAGGACTATTTCG
TGGGCTTCTTCCTGATCGGCGCCTACCAGGAGATCCTGGGGGACATGCACAACCTGTTCGGCGATACCAACGCCGTCCAC
GTCACCTTCAACAAGAAGACCGGCTACAAGATCGATACGGTCATCCATGGCGACGCCACCTGGGAGAGCCTCAAGTACGT
CCAGTACAAGGGGCCGGAGATCCTGAAGCACGTCCGCGACACCCTGGAGAAGGACGTGGCCCTTCGCAAGGTCACCATCG
AGGAGAGTAGCCATTTCCTTGAGCTGCTGGACCGGACGCTCCTGGGCTACACCTACCTGGGGGAATGA

Upstream 100 bases:

>100_bases
GATCTGGCCGAAATCTCTCGCCCCTTTGGAAAACCGTAAACTGAAAACGATTACCTAACAGCGGCGTTAGTGCGCGAATA
TGGCGTCGCCAGGAGAGCAT

Downstream 100 bases:

>100_bases
CGGAGCCCCACCCGCCCCCTTCCGACCGCTCGCACCCTCGATGCGGCCGGTTGAGCGTATCCGTTCGGATGGTAGAATTG
GATACGTGCAACGAATCGGG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MERWSINESAKIYNLPNWGADLFSINKKGNVCVHPSPTSKHSIDLRALVDDLIKRKIKPPILLRFMDVLQGRIASINRVF
KNAIDENDYPATYQTFYPIKVNQQRQVVEAIAKFGKRYNIGLEVGSKPELVIGISFATGNGIPIICNGYKDTEYIETVLY
ATKIGYDITIVVEKMFELEKIIALSKKTGIKPKLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAIGLLEQNDLLDR
VKLLHFHIGSQITKIDKIKSALIEGTRIYAEMRKLGVGIRYVDIGGGLGVDYDGSKSSYFSSVNYSIEEYANDVIYQIKN
ICEDAGVECPNIISESGRATAAHYSVLVTNLLNTNTSNAMPDFEETLNGTEKLAPTVKKLVDIYKSIDRYSLREDYHDTV
QLIQEAVSLFNLGYLTLNERAMAEWLHGKILRKINGIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFP
IVPIQRLNQKPDVMASIADITCDSDGEITSFVGENGRTKYLPLHKMRKDEDYFVGFFLIGAYQEILGDMHNLFGDTNAVH
VTFNKKTGYKIDTVIHGDATWESLKYVQYKGPEILKHVRDTLEKDVALRKVTIEESSHFLELLDRTLLGYTYLGE

Sequences:

>Translated_635_residues
MERWSINESAKIYNLPNWGADLFSINKKGNVCVHPSPTSKHSIDLRALVDDLIKRKIKPPILLRFMDVLQGRIASINRVF
KNAIDENDYPATYQTFYPIKVNQQRQVVEAIAKFGKRYNIGLEVGSKPELVIGISFATGNGIPIICNGYKDTEYIETVLY
ATKIGYDITIVVEKMFELEKIIALSKKTGIKPKLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAIGLLEQNDLLDR
VKLLHFHIGSQITKIDKIKSALIEGTRIYAEMRKLGVGIRYVDIGGGLGVDYDGSKSSYFSSVNYSIEEYANDVIYQIKN
ICEDAGVECPNIISESGRATAAHYSVLVTNLLNTNTSNAMPDFEETLNGTEKLAPTVKKLVDIYKSIDRYSLREDYHDTV
QLIQEAVSLFNLGYLTLNERAMAEWLHGKILRKINGIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFP
IVPIQRLNQKPDVMASIADITCDSDGEITSFVGENGRTKYLPLHKMRKDEDYFVGFFLIGAYQEILGDMHNLFGDTNAVH
VTFNKKTGYKIDTVIHGDATWESLKYVQYKGPEILKHVRDTLEKDVALRKVTIEESSHFLELLDRTLLGYTYLGE
>Mature_635_residues
MERWSINESAKIYNLPNWGADLFSINKKGNVCVHPSPTSKHSIDLRALVDDLIKRKIKPPILLRFMDVLQGRIASINRVF
KNAIDENDYPATYQTFYPIKVNQQRQVVEAIAKFGKRYNIGLEVGSKPELVIGISFATGNGIPIICNGYKDTEYIETVLY
ATKIGYDITIVVEKMFELEKIIALSKKTGIKPKLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAIGLLEQNDLLDR
VKLLHFHIGSQITKIDKIKSALIEGTRIYAEMRKLGVGIRYVDIGGGLGVDYDGSKSSYFSSVNYSIEEYANDVIYQIKN
ICEDAGVECPNIISESGRATAAHYSVLVTNLLNTNTSNAMPDFEETLNGTEKLAPTVKKLVDIYKSIDRYSLREDYHDTV
QLIQEAVSLFNLGYLTLNERAMAEWLHGKILRKINGIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFP
IVPIQRLNQKPDVMASIADITCDSDGEITSFVGENGRTKYLPLHKMRKDEDYFVGFFLIGAYQEILGDMHNLFGDTNAVH
VTFNKKTGYKIDTVIHGDATWESLKYVQYKGPEILKHVRDTLEKDVALRKVTIEESSHFLELLDRTLLGYTYLGE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=628, Percent_Identity=37.7388535031847, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71638; Mature: 71638

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERWSINESAKIYNLPNWGADLFSINKKGNVCVHPSPTSKHSIDLRALVDDLIKRKIKPP
CCCCCCCCCCEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCH
ILLRFMDVLQGRIASINRVFKNAIDENDYPATYQTFYPIKVNQQRQVVEAIAKFGKRYNI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHCCEEEE
GLEVGSKPELVIGISFATGNGIPIICNGYKDTEYIETVLYATKIGYDITIVVEKMFELEK
EEEECCCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
IIALSKKTGIKPKLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAIGLLEQNDLLDR
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCHHHHHHH
VKLLHFHIGSQITKIDKIKSALIEGTRIYAEMRKLGVGIRYVDIGGGLGVDYDGSKSSYF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHH
SSVNYSIEEYANDVIYQIKNICEDAGVECPNIISESGRATAAHYSVLVTNLLNTNTSNAM
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
PDFEETLNGTEKLAPTVKKLVDIYKSIDRYSLREDYHDTVQLIQEAVSLFNLGYLTLNER
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHH
AMAEWLHGKILRKINGIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHC
IVPIQRLNQKPDVMASIADITCDSDGEITSFVGENGRTKYLPLHKMRKDEDYFVGFFLIG
CCCHHHCCCCCHHHHHHHHEEECCCCCCHHHHCCCCCEEECCHHHHCCCCCCEEHHHHHH
AYQEILGDMHNLFGDTNAVHVTFNKKTGYKIDTVIHGDATWESLKYVQYKGPEILKHVRD
HHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHEEECCCHHHHHHHHH
TLEKDVALRKVTIEESSHFLELLDRTLLGYTYLGE
HHHHHHHHEEEEHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERWSINESAKIYNLPNWGADLFSINKKGNVCVHPSPTSKHSIDLRALVDDLIKRKIKPP
CCCCCCCCCCEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCH
ILLRFMDVLQGRIASINRVFKNAIDENDYPATYQTFYPIKVNQQRQVVEAIAKFGKRYNI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHCCEEEE
GLEVGSKPELVIGISFATGNGIPIICNGYKDTEYIETVLYATKIGYDITIVVEKMFELEK
EEEECCCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
IIALSKKTGIKPKLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAIGLLEQNDLLDR
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCHHHHHHH
VKLLHFHIGSQITKIDKIKSALIEGTRIYAEMRKLGVGIRYVDIGGGLGVDYDGSKSSYF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHH
SSVNYSIEEYANDVIYQIKNICEDAGVECPNIISESGRATAAHYSVLVTNLLNTNTSNAM
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
PDFEETLNGTEKLAPTVKKLVDIYKSIDRYSLREDYHDTVQLIQEAVSLFNLGYLTLNER
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHH
AMAEWLHGKILRKINGIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHC
IVPIQRLNQKPDVMASIADITCDSDGEITSFVGENGRTKYLPLHKMRKDEDYFVGFFLIG
CCCHHHCCCCCHHHHHHHHEEECCCCCCHHHHCCCCCEEECCHHHHCCCCCCEEHHHHHH
AYQEILGDMHNLFGDTNAVHVTFNKKTGYKIDTVIHGDATWESLKYVQYKGPEILKHVRD
HHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHEEECCCHHHHHHHHH
TLEKDVALRKVTIEESSHFLELLDRTLLGYTYLGE
HHHHHHHHEEEEHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA