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The map label for this gene is mtbA [H]

Identifier: 39997481

GI number: 39997481

Start: 2615333

End: 2616358

Strand: Reverse

Name: mtbA [H]

Synonym: GSU2386

Alternate gene names: 39997481

Gene position: 2616358-2615333 (Counterclockwise)

Preceding gene: 39997482

Following gene: 39997480

Centisome position: 68.6

GC content: 68.13

Gene sequence:

>1026_bases
ATGACATCGTTCGAACGGGTCATGGCCGCCATGGGGGGTGTTGAAACCGACCGTCCGCCGTTCACCCTCACCCTGAGCCT
GTACGGCGCCCGGCTGATCGGCGCGTCGCCGGAGCAGTACTACACGTCGCCGCGTCTCTACGCCGAGGGGCAGGATCGCG
TGGCGGAGCTCTTCGGGCCGGACATCCTCTTTGCTCCCTTTGCCCTTGCCCGCGAGGCCGAGGCCTTCGGCAGCACCGTC
GTCTACCACCGGCACGGCCCCCCCAACGTGGTCAAGCCGGTGGTGAAGAATGCCGCCGATTTCATGCGCCTCGCCGATCC
CGACCCTGACGCGCACCCGGCCCTCCTCTACCTGCGGGAGAGCGTCCGGCTCCTGGCGGACGGGTACAAGGGACGGGTTC
CCCTGGCCGGCATCCTCACCGCGCCCGTGGATCTCCCCGCCATCATCATGGGGATCGACGCGTGGCTGGAGACGCTGCTC
TTCGAGCCGGAACTGGCATCAGCGGTGCTGGAAAAGACCGGCCGCCATTTCGTGGCCATGGCGAGCCGCCTCCTGGGCGA
CGGCGCCGATTTCGTGGCCATGCCGGTCATGTTCTTCAATACGGCGCTGGTTACTTCGCGGATTGCGGCCGAGCGGATCG
TGCCGGCCCTGGCGGCGGCCTTTGCGCAGGTGCCGGGTCCCCTGGTGTTCCATCACGGCGGCAACCGGATCGCCCCCTTT
CTCGGAGAACTGGCCGAGCTCCCCGGCGTGGCCGGTTTCGTCATTGATCCGCGGGACAGCTTCCAGGACGCCCGTGCCAG
GGTCGGCGACGGACGGGTCCTGCTCGGCAAGCTCAACGGGCCGCTGCTCGGCCTGCTGACTCCCGACGACGCCTGCCGCG
TCACGGCAGAAATCCTGGCCGACCGCCGGGACGACCGCCATTTCATCTTTGCCTCCTCGGCCGCGGACGTGCCCTGGAAT
ACCCCGCCGGAAACCATCTCCGCGGTTGCGGATACCATCCGGCAGTGGCAGCGCCATGGACAATAA

Upstream 100 bases:

>100_bases
TGGCTGAAGTGGGCGGAGACGGCACTGCCGACAGCGCCCTGGCCGCGCCGACGCTGTTCGATGAATTGTGGCGCCGCGCC
CATGACCGGAGTGATGCGGC

Downstream 100 bases:

>100_bases
CGCGCTGGGGCCAGGGCATGCGACGGTGGTGAGCTGCGGCATCTTCCGGCCGGAGATCGAGCATCTCGCGCGGCAGGGGC
GCTTCCCCTGGCCCGTACGC

Product: methylcobamide:CoM methyltransferase-related protein

Products: NA

Alternate protein names: MT2-A; Methylcobamide:CoM methyltransferase II isozyme A [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTSFERVMAAMGGVETDRPPFTLTLSLYGARLIGASPEQYYTSPRLYAEGQDRVAELFGPDILFAPFALAREAEAFGSTV
VYHRHGPPNVVKPVVKNAADFMRLADPDPDAHPALLYLRESVRLLADGYKGRVPLAGILTAPVDLPAIIMGIDAWLETLL
FEPELASAVLEKTGRHFVAMASRLLGDGADFVAMPVMFFNTALVTSRIAAERIVPALAAAFAQVPGPLVFHHGGNRIAPF
LGELAELPGVAGFVIDPRDSFQDARARVGDGRVLLGKLNGPLLGLLTPDDACRVTAEILADRRDDRHFIFASSAADVPWN
TPPETISAVADTIRQWQRHGQ

Sequences:

>Translated_341_residues
MTSFERVMAAMGGVETDRPPFTLTLSLYGARLIGASPEQYYTSPRLYAEGQDRVAELFGPDILFAPFALAREAEAFGSTV
VYHRHGPPNVVKPVVKNAADFMRLADPDPDAHPALLYLRESVRLLADGYKGRVPLAGILTAPVDLPAIIMGIDAWLETLL
FEPELASAVLEKTGRHFVAMASRLLGDGADFVAMPVMFFNTALVTSRIAAERIVPALAAAFAQVPGPLVFHHGGNRIAPF
LGELAELPGVAGFVIDPRDSFQDARARVGDGRVLLGKLNGPLLGLLTPDDACRVTAEILADRRDDRHFIFASSAADVPWN
TPPETISAVADTIRQWQRHGQ
>Mature_340_residues
TSFERVMAAMGGVETDRPPFTLTLSLYGARLIGASPEQYYTSPRLYAEGQDRVAELFGPDILFAPFALAREAEAFGSTVV
YHRHGPPNVVKPVVKNAADFMRLADPDPDAHPALLYLRESVRLLADGYKGRVPLAGILTAPVDLPAIIMGIDAWLETLLF
EPELASAVLEKTGRHFVAMASRLLGDGADFVAMPVMFFNTALVTSRIAAERIVPALAAAFAQVPGPLVFHHGGNRIAPFL
GELAELPGVAGFVIDPRDSFQDARARVGDGRVLLGKLNGPLLGLLTPDDACRVTAEILADRRDDRHFIFASSAADVPWNT
PPETISAVADTIRQWQRHGQ

Specific function: Catalyzes the transfer of the methyl group from the methylated corrinoid cofactor of mtmC, mtbC and mttC to coenzyme M [H]

COG id: COG0407

COG function: function code H; Uroporphyrinogen-III decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uroporphyrinogen decarboxylase family. MtbA/mtaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006360
- InterPro:   IPR000257 [H]

Pfam domain/function: PF01208 URO-D [H]

EC number: NA

Molecular weight: Translated: 36873; Mature: 36742

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFERVMAAMGGVETDRPPFTLTLSLYGARLIGASPEQYYTSPRLYAEGQDRVAELFGP
CCHHHHHHHHHCCCCCCCCCEEEEEEECCCHHCCCCCHHHCCCCCEEECCHHHHHHHHCC
DILFAPFALAREAEAFGSTVVYHRHGPPNVVKPVVKNAADFMRLADPDPDAHPALLYLRE
CHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
SVRLLADGYKGRVPLAGILTAPVDLPAIIMGIDAWLETLLFEPELASAVLEKTGRHFVAM
HHHHHHCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHH
ASRLLGDGADFVAMPVMFFNTALVTSRIAAERIVPALAAAFAQVPGPLVFHHGGNRIAPF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHH
LGELAELPGVAGFVIDPRDSFQDARARVGDGRVLLGKLNGPLLGLLTPDDACRVTAEILA
HHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHH
DRRDDRHFIFASSAADVPWNTPPETISAVADTIRQWQRHGQ
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSFERVMAAMGGVETDRPPFTLTLSLYGARLIGASPEQYYTSPRLYAEGQDRVAELFGP
CHHHHHHHHHCCCCCCCCCEEEEEEECCCHHCCCCCHHHCCCCCEEECCHHHHHHHHCC
DILFAPFALAREAEAFGSTVVYHRHGPPNVVKPVVKNAADFMRLADPDPDAHPALLYLRE
CHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
SVRLLADGYKGRVPLAGILTAPVDLPAIIMGIDAWLETLLFEPELASAVLEKTGRHFVAM
HHHHHHCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHH
ASRLLGDGADFVAMPVMFFNTALVTSRIAAERIVPALAAAFAQVPGPLVFHHGGNRIAPF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHH
LGELAELPGVAGFVIDPRDSFQDARARVGDGRVLLGKLNGPLLGLLTPDDACRVTAEILA
HHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHH
DRRDDRHFIFASSAADVPWNTPPETISAVADTIRQWQRHGQ
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]