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The map label for this gene is aphA [H]

Identifier: 39997395

GI number: 39997395

Start: 2514738

End: 2517026

Strand: Reverse

Name: aphA [H]

Synonym: GSU2297

Alternate gene names: 39997395

Gene position: 2517026-2514738 (Counterclockwise)

Preceding gene: 39997396

Following gene: 39997393

Centisome position: 65.99

GC content: 58.67

Gene sequence:

>2289_bases
ATGAATCTCAAACAAAGAATGACACTCGCCATTTCGGCGTTGATGGTTTTGTTCGCCGTGTTCATGGCGGTCGTTGCGGT
CGGCTATTTCGAGCGCAAACTCAACGAGACCATTATCGATCAGCAAAGTTCGCTGGTCAGCTACATTGCCGGTGAAATCG
ACAATACCCTCGGCATTGCCCAGGGTCTTCTCGTTGCCAGCGCCACCTTCGTTCCCGCCGACGCCCTTGATTCCCCGGAG
CGAACCCGGCGATTCCTCCAGAGCAGGACAAGCCTCAACAAACTGTTCGGCAACCGGTTGCTGGTCATCTCCGCCGACGG
ACGGCTGGTCGCCACATCCCATAACGTTGCCGGAAGCAACCCTCCGTCCAATTTTACCGACACCCCCTTTTTTCGCGAAA
CTCTCAGGAAACGAATTCCACTCATCTCCGAGATGACGACCTGCTGTATCTCGCCCCATTCTTCGGAAATCGTCATGACC
GCGCCGATCTTTGGCCCGGGCAACCAGGTACGGGGAGTTCTCGCCGGGACCATCGCCCTGCGTGAGACGAACCTGCTGTC
GCGTTTCGGCACCCTTCGCATCGGCAAAACAGGCTATCTTCAGCTGGCAACGGCTAACCAGACATTGATAGTGCACCCTG
AGCGCGAGTGTATCCTGCATCAGGTCGGACCTCTACACGGCAATCTCGTGACCGACGCCGTCAAGGGGTTTTCCGGCACC
CGGCGTACGGTGAACAACAAGGGAGTGCCCATGTTCACCACGGCGCGCAAGCTGGCGTTGAAAGATTGGGTAGTGATGGC
CAACTACCCGGAAAAAGAGGTGTTGGCGCCCATACGTGCCGCCAGGGGTGTTATGGGGGTCTTTACGGTAGCGGGGGTTG
GCGCGCTGATCATTCTCACCTCCCTATCGATCGGCTATCTCACCCGTCAACTGACAGCATTCACCGAGCATATCCGCGGG
CTTTCCGAAAAGGAGGGCGCCGACCGCCGGTTCCCCATGCCCGATACCGGTGACGAGATCTCCGCACTGTCGACCGCATT
CAATGAGATGGTGACGTCGCTTGACCAGCGGACCGAGAGCCTGTGCGAGAGCGAAGAGCGGTTTCGCAGTACGTTCGAGC
AGGCTGCGGTCGGTATTGCCCATGTGGATATGGATGGACGGTTTATCAGGCTCAATAGTCGCTTCAGCGACATCCTCGGC
TATGCCGAGCACGAATTGCTCGGTATGACCGTTGCCGATATTACCTGTCCGGAATATCTGGAGAGCTGCCAATCCTGCCG
GCAGCAACTTCTTGAAGGAAAGCGTTCGTGTGCCGCAGAAAACCGCTATCTCCGCAAAGGGGGAGCACACGTCTGGGTCA
ACCAGACGGCATCGGTACTGCTGGATTCATCGGACAAGCCAAAGTATTTCATCATGGTCATCGAGGATATTTCGGCCCGG
AAAGGGGCCGAGGAAGAGGTCCGCCGGCTCAATGCGGGCCTTGAGCAGCGGGTCGCCGAGCGGACCGCTGAACTGGAGTC
GGTCAACATCCGTCTCATGGCGGAAATTGAGCAGCGGGCCCAGGCACAGGAGGAGATCGGTTGGCTGAACGAGGATCTCA
TGCGGCAGAAGGCGGCCCTGGAAGCCGCGAATCGAGAACTGGAGGCGTTCAGCTACTCGGTTTCCCATGATCTGCGAGCA
CCCCTGCGGCATATTGCCGGCTATGGCCTCGCCCTTCGGGAAGACTACGGCGGGCAGCTCGATCCGCAGGCTCTCGAGTT
CATCGAGCGGATGAACGCAGCCGCTCGACGGATGGAGCAGCTGATCGAAGCTATGCTCAACCTGTCGCGGCTGGGGCAGG
GTGACGTCAAGCGTATGCCTATCGACATGAGCGCCATGGCACGCGAGGTCGTGGCCGGCTTGCGCGAGGCCGAACCGAAC
AGGAATGTAGTGATTACCATTGCCGATGGGCTCACTGCCACAGGGGATCCCCAGCTTATGCGCATTGTTCTGGAAAATTT
ACTGGGAAATGCGTGGAAATATACGGGCAGATCGCCGCTGGCCGAAATTGAGTTCAGTGCTCTGACCGACGGGCAGCCGG
CGTTTTGCGTGAGGGATAACGGAGCGGGATTCGACATGGCCTTTGCCGATAGGCTGTTCGGACCGTTCCAGCGGTTACAC
CGTGATGACGAATTCGCCGGAACCGGCATCGGCCTTGCCACGGTCCAGCGCATTATCAACCGGCACCGGGGAAGCATCTG
GGCCGAGAGTGCACCCGGCGCCGGTGCTGTGTTCTACTTCTCAATCTGA

Upstream 100 bases:

>100_bases
CAACGATAATAAGAACGGCCATGACCCATGGAGGGGGCTTGGATACGCAGCTCTGAAGGCGTTTTGCCACGCTTCGGCAA
CAACCGCGTGGGTTCGGGTA

Downstream 100 bases:

>100_bases
TAGCGGTCGGGTTGGGAAGGAAATGATGTGTTCAGCGGTGCGCGGGGGAGGGACGGGGATAGCTCAGAGGAGGAACAGTT
CGTCGACGGCAGCCCGAATT

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MNLKQRMTLAISALMVLFAVFMAVVAVGYFERKLNETIIDQQSSLVSYIAGEIDNTLGIAQGLLVASATFVPADALDSPE
RTRRFLQSRTSLNKLFGNRLLVISADGRLVATSHNVAGSNPPSNFTDTPFFRETLRKRIPLISEMTTCCISPHSSEIVMT
APIFGPGNQVRGVLAGTIALRETNLLSRFGTLRIGKTGYLQLATANQTLIVHPERECILHQVGPLHGNLVTDAVKGFSGT
RRTVNNKGVPMFTTARKLALKDWVVMANYPEKEVLAPIRAARGVMGVFTVAGVGALIILTSLSIGYLTRQLTAFTEHIRG
LSEKEGADRRFPMPDTGDEISALSTAFNEMVTSLDQRTESLCESEERFRSTFEQAAVGIAHVDMDGRFIRLNSRFSDILG
YAEHELLGMTVADITCPEYLESCQSCRQQLLEGKRSCAAENRYLRKGGAHVWVNQTASVLLDSSDKPKYFIMVIEDISAR
KGAEEEVRRLNAGLEQRVAERTAELESVNIRLMAEIEQRAQAQEEIGWLNEDLMRQKAALEAANRELEAFSYSVSHDLRA
PLRHIAGYGLALREDYGGQLDPQALEFIERMNAAARRMEQLIEAMLNLSRLGQGDVKRMPIDMSAMAREVVAGLREAEPN
RNVVITIADGLTATGDPQLMRIVLENLLGNAWKYTGRSPLAEIEFSALTDGQPAFCVRDNGAGFDMAFADRLFGPFQRLH
RDDEFAGTGIGLATVQRIINRHRGSIWAESAPGAGAVFYFSI

Sequences:

>Translated_762_residues
MNLKQRMTLAISALMVLFAVFMAVVAVGYFERKLNETIIDQQSSLVSYIAGEIDNTLGIAQGLLVASATFVPADALDSPE
RTRRFLQSRTSLNKLFGNRLLVISADGRLVATSHNVAGSNPPSNFTDTPFFRETLRKRIPLISEMTTCCISPHSSEIVMT
APIFGPGNQVRGVLAGTIALRETNLLSRFGTLRIGKTGYLQLATANQTLIVHPERECILHQVGPLHGNLVTDAVKGFSGT
RRTVNNKGVPMFTTARKLALKDWVVMANYPEKEVLAPIRAARGVMGVFTVAGVGALIILTSLSIGYLTRQLTAFTEHIRG
LSEKEGADRRFPMPDTGDEISALSTAFNEMVTSLDQRTESLCESEERFRSTFEQAAVGIAHVDMDGRFIRLNSRFSDILG
YAEHELLGMTVADITCPEYLESCQSCRQQLLEGKRSCAAENRYLRKGGAHVWVNQTASVLLDSSDKPKYFIMVIEDISAR
KGAEEEVRRLNAGLEQRVAERTAELESVNIRLMAEIEQRAQAQEEIGWLNEDLMRQKAALEAANRELEAFSYSVSHDLRA
PLRHIAGYGLALREDYGGQLDPQALEFIERMNAAARRMEQLIEAMLNLSRLGQGDVKRMPIDMSAMAREVVAGLREAEPN
RNVVITIADGLTATGDPQLMRIVLENLLGNAWKYTGRSPLAEIEFSALTDGQPAFCVRDNGAGFDMAFADRLFGPFQRLH
RDDEFAGTGIGLATVQRIINRHRGSIWAESAPGAGAVFYFSI
>Mature_762_residues
MNLKQRMTLAISALMVLFAVFMAVVAVGYFERKLNETIIDQQSSLVSYIAGEIDNTLGIAQGLLVASATFVPADALDSPE
RTRRFLQSRTSLNKLFGNRLLVISADGRLVATSHNVAGSNPPSNFTDTPFFRETLRKRIPLISEMTTCCISPHSSEIVMT
APIFGPGNQVRGVLAGTIALRETNLLSRFGTLRIGKTGYLQLATANQTLIVHPERECILHQVGPLHGNLVTDAVKGFSGT
RRTVNNKGVPMFTTARKLALKDWVVMANYPEKEVLAPIRAARGVMGVFTVAGVGALIILTSLSIGYLTRQLTAFTEHIRG
LSEKEGADRRFPMPDTGDEISALSTAFNEMVTSLDQRTESLCESEERFRSTFEQAAVGIAHVDMDGRFIRLNSRFSDILG
YAEHELLGMTVADITCPEYLESCQSCRQQLLEGKRSCAAENRYLRKGGAHVWVNQTASVLLDSSDKPKYFIMVIEDISAR
KGAEEEVRRLNAGLEQRVAERTAELESVNIRLMAEIEQRAQAQEEIGWLNEDLMRQKAALEAANRELEAFSYSVSHDLRA
PLRHIAGYGLALREDYGGQLDPQALEFIERMNAAARRMEQLIEAMLNLSRLGQGDVKRMPIDMSAMAREVVAGLREAEPN
RNVVITIADGLTATGDPQLMRIVLENLLGNAWKYTGRSPLAEIEFSALTDGQPAFCVRDNGAGFDMAFADRLFGPFQRLH
RDDEFAGTGIGLATVQRIINRHRGSIWAESAPGAGAVFYFSI

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=208, Percent_Identity=29.3269230769231, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788381, Length=141, Percent_Identity=31.9148936170213, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=30.0847457627119, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=208, Percent_Identity=29.8076923076923, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=214, Percent_Identity=31.3084112149533, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=218, Percent_Identity=28.8990825688073, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=222, Percent_Identity=23.4234234234234, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=23.6286919831224, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84027; Mature: 84027

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQRMTLAISALMVLFAVFMAVVAVGYFERKLNETIIDQQSSLVSYIAGEIDNTLGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLLVASATFVPADALDSPERTRRFLQSRTSLNKLFGNRLLVISADGRLVATSHNVAGSN
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCCCC
PPSNFTDTPFFRETLRKRIPLISEMTTCCISPHSSEIVMTAPIFGPGNQVRGVLAGTIAL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
RETNLLSRFGTLRIGKTGYLQLATANQTLIVHPERECILHQVGPLHGNLVTDAVKGFSGT
HHHHHHHHHCCEEECCCCEEEEEECCCEEEECCHHHHHHHHCCCCCCCHHHHHHHCCCCC
RRTVNNKGVPMFTTARKLALKDWVVMANYPEKEVLAPIRAARGVMGVFTVAGVGALIILT
CCCCCCCCCCEEHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSIGYLTRQLTAFTEHIRGLSEKEGADRRFPMPDTGDEISALSTAFNEMVTSLDQRTES
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LCESEERFRSTFEQAAVGIAHVDMDGRFIRLNSRFSDILGYAEHELLGMTVADITCPEYL
HHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCHHHHCCCHHHH
ESCQSCRQQLLEGKRSCAAENRYLRKGGAHVWVNQTASVLLDSSDKPKYFIMVIEDISAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEEECCCCC
KGAEEEVRRLNAGLEQRVAERTAELESVNIRLMAEIEQRAQAQEEIGWLNEDLMRQKAAL
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EAANRELEAFSYSVSHDLRAPLRHIAGYGLALREDYGGQLDPQALEFIERMNAAARRMEQ
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LIEAMLNLSRLGQGDVKRMPIDMSAMAREVVAGLREAEPNRNVVITIADGLTATGDPQLM
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHH
RIVLENLLGNAWKYTGRSPLAEIEFSALTDGQPAFCVRDNGAGFDMAFADRLFGPFQRLH
HHHHHHHHCCCEECCCCCCCHHEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
RDDEFAGTGIGLATVQRIINRHRGSIWAESAPGAGAVFYFSI
CCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEEEC
>Mature Secondary Structure
MNLKQRMTLAISALMVLFAVFMAVVAVGYFERKLNETIIDQQSSLVSYIAGEIDNTLGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLLVASATFVPADALDSPERTRRFLQSRTSLNKLFGNRLLVISADGRLVATSHNVAGSN
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCCCC
PPSNFTDTPFFRETLRKRIPLISEMTTCCISPHSSEIVMTAPIFGPGNQVRGVLAGTIAL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
RETNLLSRFGTLRIGKTGYLQLATANQTLIVHPERECILHQVGPLHGNLVTDAVKGFSGT
HHHHHHHHHCCEEECCCCEEEEEECCCEEEECCHHHHHHHHCCCCCCCHHHHHHHCCCCC
RRTVNNKGVPMFTTARKLALKDWVVMANYPEKEVLAPIRAARGVMGVFTVAGVGALIILT
CCCCCCCCCCEEHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSIGYLTRQLTAFTEHIRGLSEKEGADRRFPMPDTGDEISALSTAFNEMVTSLDQRTES
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LCESEERFRSTFEQAAVGIAHVDMDGRFIRLNSRFSDILGYAEHELLGMTVADITCPEYL
HHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCHHHHCCCHHHH
ESCQSCRQQLLEGKRSCAAENRYLRKGGAHVWVNQTASVLLDSSDKPKYFIMVIEDISAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEEECCCCC
KGAEEEVRRLNAGLEQRVAERTAELESVNIRLMAEIEQRAQAQEEIGWLNEDLMRQKAAL
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EAANRELEAFSYSVSHDLRAPLRHIAGYGLALREDYGGQLDPQALEFIERMNAAARRMEQ
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LIEAMLNLSRLGQGDVKRMPIDMSAMAREVVAGLREAEPNRNVVITIADGLTATGDPQLM
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHH
RIVLENLLGNAWKYTGRSPLAEIEFSALTDGQPAFCVRDNGAGFDMAFADRLFGPFQRLH
HHHHHHHHCCCEECCCCCCCHHEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
RDDEFAGTGIGLATVQRIINRHRGSIWAESAPGAGAVFYFSI
CCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]