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The map label for this gene is fabZ

Identifier: 39997363

GI number: 39997363

Start: 2480851

End: 2481303

Strand: Reverse

Name: fabZ

Synonym: GSU2265

Alternate gene names: 39997363

Gene position: 2481303-2480851 (Counterclockwise)

Preceding gene: 39997364

Following gene: 39997362

Centisome position: 65.06

GC content: 57.62

Gene sequence:

>453_bases
ATGGAAACAGTCTTTGATATCAACGAAATCATGAAGATTCTTCCCCACCGCTACCCCTTCCTCCTGGTGGATCGGATTGT
GGAGTACGTTGCCGGCGAGCGGATCGTGGGGATCAAGAACGTCAGCATCAATGAGCCGTTTTTCCAAGGCCACTTTCCGG
GACACCCGGTGATGCCGGGAGTCCTGATCGTTGAGGCCATGGCCCAGGTGGGGGGAATCTACGCCTATGTGACCTTGGGC
GACGAGGTCCGCGACAAGGTCTGCTACTTTGCCTCCATCGACAACGTCAAGTTCCGCAAACCGGTGGTGCCGGGAGACCA
ACTGCGGATCGAAGTAACGATCTCCGGTTGCAAGCGGGGCATCTGGTGCTTCAGCGCCAGGGCCACCGTGAACGGCAAGC
TGGTCACCGAGGCGGAGCTCAAGGCGACCTTTGCCGACAAGGAAAAACTCTAA

Upstream 100 bases:

>100_bases
CCGGCTCCGCACCGGTTTGTTTCGCTATTTTCGGTCGTGTAATCGAGAAAACGCGACTGTCCTCCGGGCGGTCCGTTTTT
CTCTTTTGAGGAGCGTGAAC

Downstream 100 bases:

>100_bases
ATGATTCATCCTACGGCAATCGTGCATCCCGGGGCGGAAATCGCCGAGGGTGTAGAAATCGGCCCCTATGTCATTATCGG
GGCGCACGTTCGTATCGGAC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
METVFDINEIMKILPHRYPFLLVDRIVEYVAGERIVGIKNVSINEPFFQGHFPGHPVMPGVLIVEAMAQVGGIYAYVTLG
DEVRDKVCYFASIDNVKFRKPVVPGDQLRIEVTISGCKRGIWCFSARATVNGKLVTEAELKATFADKEKL

Sequences:

>Translated_150_residues
METVFDINEIMKILPHRYPFLLVDRIVEYVAGERIVGIKNVSINEPFFQGHFPGHPVMPGVLIVEAMAQVGGIYAYVTLG
DEVRDKVCYFASIDNVKFRKPVVPGDQLRIEVTISGCKRGIWCFSARATVNGKLVTEAELKATFADKEKL
>Mature_150_residues
METVFDINEIMKILPHRYPFLLVDRIVEYVAGERIVGIKNVSINEPFFQGHFPGHPVMPGVLIVEAMAQVGGIYAYVTLG
DEVRDKVCYFASIDNVKFRKPVVPGDQLRIEVTISGCKRGIWCFSARATVNGKLVTEAELKATFADKEKL

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=51.8248175182482, Blast_Score=157, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_GEOSL (P61453)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953314.1
- ProteinModelPortal:   P61453
- SMR:   P61453
- GeneID:   2687474
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2265
- NMPDR:   fig|243231.1.peg.2252
- TIGR:   GSU2265
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   GSUL243231:GSU_2265-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16803; Mature: 16803

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: ACT_SITE 51-51

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVFDINEIMKILPHRYPFLLVDRIVEYVAGERIVGIKNVSINEPFFQGHFPGHPVMPG
CCCEECHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCCCCCCCCCH
VLIVEAMAQVGGIYAYVTLGDEVRDKVCYFASIDNVKFRKPVVPGDQLRIEVTISGCKRG
HHHHHHHHHHCCEEEEEEECHHHHHHEEEEEECCCCEEECCCCCCCCEEEEEEECCCCCC
IWCFSARATVNGKLVTEAELKATFADKEKL
EEEEEECEEECCEEEEHHHHHEECCCCCCC
>Mature Secondary Structure
METVFDINEIMKILPHRYPFLLVDRIVEYVAGERIVGIKNVSINEPFFQGHFPGHPVMPG
CCCEECHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCCCCCCCCCH
VLIVEAMAQVGGIYAYVTLGDEVRDKVCYFASIDNVKFRKPVVPGDQLRIEVTISGCKRG
HHHHHHHHHHCCEEEEEEECHHHHHHEEEEEECCCCEEECCCCCCCCEEEEEEECCCCCC
IWCFSARATVNGKLVTEAELKATFADKEKL
EEEEEECEEECCEEEEHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA