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The map label for this gene is era [H]

Identifier: 39997324

GI number: 39997324

Start: 2442138

End: 2443037

Strand: Reverse

Name: era [H]

Synonym: GSU2226

Alternate gene names: 39997324

Gene position: 2443037-2442138 (Counterclockwise)

Preceding gene: 39997325

Following gene: 39997323

Centisome position: 64.05

GC content: 61.33

Gene sequence:

>900_bases
ATGTTGTCGAAAACGCCATTCCGCTCGGGCTTTGTCTCGATCATCGGCCGCCCCAACGTGGGGAAGTCGACGCTTCTCAA
CCGGATCCTCGGGGAAAAGATCGTCATCACCTCGGACAAACCCCAGACGACCCGCAACCGCATCCAGGGAATCCACAATC
TGCCCGGCGCCCAGATCGTGTTCATCGACACGCCGGGAATCCACCACGCCCGTTCGCGGCTCAACAAATTCATGGTGGAG
GAGGCCCTTTCCTCCATCCGCGAGGTAGATCTGGTCATGCTGCTGGTGGAGGCCAACCGGGCTCCGGGCGACCAGGAGCG
GGAGATCGCGGGACTTCTGCCCAGTGTGAATGTGCCCGTTTTCCTTGTTGTCAACAAGATCGACCTCATCGATCCGGACA
TCCTGGCCGAGCGGCTCACCGCCTATGCCGAACTGTTTCCCTTCCGCGAAGTGGTGCCGGTTTCCGCGGAAACCGGTGAG
AATGTGGAGCGGCTGGTAGAGGTGGTGCGCGATACCCTGCCCGAGGGGCCGGTCTACTTCCCGGACGACATCCTTACGGA
TTTGCCCGAGCGGTTCATTGTGGCCGAGATCGTGCGGGAAAAGGTCTTTCGCCTCACCCGGGACGAGATTCCCTACTCCA
CCGCCGTGGAGGTGGACAGCTTTCGGGAGCGGGAGGACGGCGGCCTCGTCTCCATTTCCGCCACCATCACGGTGGAGCGC
GATTCCCAGAAGGGGATCATTATCGGCCGCAAGGGGGCCATGCTCAAGCAGATCGGCAGCGAGGCCCGGCTGGAGATCGA
GCGGTTGCTCGACACGAAGGTGTTTCTGGAACTCTTCGTGCGGGTCCGCAGGGACTGGAGCGAAAACCCGAATATACTCA
AGGAGCTCGGATACCGATGA

Upstream 100 bases:

>100_bases
CACCCGATACCCTTACCCTGACTCACGCCGGCGGCACCGTTGCCGGCAGTCTGACAGACTGAACGCCGCCCTTGCAGCGG
CCACACTCACAAGGAGTACT

Downstream 100 bases:

>100_bases
TACTGCCGATCGTTGCCATAGTAGGTCGCCCCAATGTGGGCAAGTCGACCCTTTTCAACCGTCTCGTGGGGCGCCGCAAG
GCGATAGTTGACGATATGCC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLSKTPFRSGFVSIIGRPNVGKSTLLNRILGEKIVITSDKPQTTRNRIQGIHNLPGAQIVFIDTPGIHHARSRLNKFMVE
EALSSIREVDLVMLLVEANRAPGDQEREIAGLLPSVNVPVFLVVNKIDLIDPDILAERLTAYAELFPFREVVPVSAETGE
NVERLVEVVRDTLPEGPVYFPDDILTDLPERFIVAEIVREKVFRLTRDEIPYSTAVEVDSFREREDGGLVSISATITVER
DSQKGIIIGRKGAMLKQIGSEARLEIERLLDTKVFLELFVRVRRDWSENPNILKELGYR

Sequences:

>Translated_299_residues
MLSKTPFRSGFVSIIGRPNVGKSTLLNRILGEKIVITSDKPQTTRNRIQGIHNLPGAQIVFIDTPGIHHARSRLNKFMVE
EALSSIREVDLVMLLVEANRAPGDQEREIAGLLPSVNVPVFLVVNKIDLIDPDILAERLTAYAELFPFREVVPVSAETGE
NVERLVEVVRDTLPEGPVYFPDDILTDLPERFIVAEIVREKVFRLTRDEIPYSTAVEVDSFREREDGGLVSISATITVER
DSQKGIIIGRKGAMLKQIGSEARLEIERLLDTKVFLELFVRVRRDWSENPNILKELGYR
>Mature_299_residues
MLSKTPFRSGFVSIIGRPNVGKSTLLNRILGEKIVITSDKPQTTRNRIQGIHNLPGAQIVFIDTPGIHHARSRLNKFMVE
EALSSIREVDLVMLLVEANRAPGDQEREIAGLLPSVNVPVFLVVNKIDLIDPDILAERLTAYAELFPFREVVPVSAETGE
NVERLVEVVRDTLPEGPVYFPDDILTDLPERFIVAEIVREKVFRLTRDEIPYSTAVEVDSFREREDGGLVSISATITVER
DSQKGIIIGRKGAMLKQIGSEARLEIERLLDTKVFLELFVRVRRDWSENPNILKELGYR

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=321, Percent_Identity=25.5451713395639, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=44.8630136986301, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI87082120, Length=160, Percent_Identity=35.625, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367268, Length=172, Percent_Identity=28.4883720930233, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=164, Percent_Identity=29.8780487804878, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646434, Length=293, Percent_Identity=26.6211604095563, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33720; Mature: 33720

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKTPFRSGFVSIIGRPNVGKSTLLNRILGEKIVITSDKPQTTRNRIQGIHNLPGAQIV
CCCCCCCCCCHHHEECCCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCEEE
FIDTPGIHHARSRLNKFMVEEALSSIREVDLVMLLVEANRAPGDQEREIAGLLPSVNVPV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCCCCCCE
FLVVNKIDLIDPDILAERLTAYAELFPFREVVPVSAETGENVERLVEVVRDTLPEGPVYF
EEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
PDDILTDLPERFIVAEIVREKVFRLTRDEIPYSTAVEVDSFREREDGGLVSISATITVER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHCCCCCEEEEEEEEEEEE
DSQKGIIIGRKGAMLKQIGSEARLEIERLLDTKVFLELFVRVRRDWSENPNILKELGYR
CCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure
MLSKTPFRSGFVSIIGRPNVGKSTLLNRILGEKIVITSDKPQTTRNRIQGIHNLPGAQIV
CCCCCCCCCCHHHEECCCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCEEE
FIDTPGIHHARSRLNKFMVEEALSSIREVDLVMLLVEANRAPGDQEREIAGLLPSVNVPV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCCCCCCE
FLVVNKIDLIDPDILAERLTAYAELFPFREVVPVSAETGENVERLVEVVRDTLPEGPVYF
EEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
PDDILTDLPERFIVAEIVREKVFRLTRDEIPYSTAVEVDSFREREDGGLVSISATITVER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHCCCCCEEEEEEEEEEEE
DSQKGIIIGRKGAMLKQIGSEARLEIERLLDTKVFLELFVRVRRDWSENPNILKELGYR
CCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA