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The map label for this gene is argJ

Identifier: 39997147

GI number: 39997147

Start: 2248053

End: 2249234

Strand: Reverse

Name: argJ

Synonym: GSU2049

Alternate gene names: 39997147

Gene position: 2249234-2248053 (Counterclockwise)

Preceding gene: 39997148

Following gene: 39997146

Centisome position: 58.97

GC content: 63.03

Gene sequence:

>1182_bases
ATGAATGTCAAGGGATTTCGGTTCTCGGCCGTTGAAGCGGCCATTAAGAAGCCGGGCCGTCTGGACTTGGCCCTCATCTG
CTCGGACGCGCCCGCTGCAGTTGCCGCGGTTTACACCACCAACAAGGTGAAGGCAGCGCCGGTGCTTCTGGACATGGAGC
GAACCACGAGCGGCACCTGCCGCGCGGTGGTGGTCAACAGCGGCAACGCCAATGCCTGCACCGGAGACCGGGGGATGGAG
GACGCGCGGGAAACCACCAGCCTCGTGGCCGAACGGATTGGTGCATCTGAGCACGAGGTGCTCGTATGCTCTACCGGCGT
GATCGGCGTGCCGCTCCCCATGGAGCGGATCAGGGGAGGGATTCCTTCCCTCGTGGCCGGGCTGGGTTCAGCGACCCTCG
ATCAGATCGCCGCGGCCATCATGACAACCGACACCTTCCCGAAACTGGAGGCGCGTACCGGGACTGCGGGAGGCGTCGGG
TACACCATCGCCGGTATCGCCAAGGGCGCCGGCATGATCATGCCGAACATGGCCACCATGCTCGCCTTTGTCGTCACCGA
TGCCGCAGTGGACCCCCAGTGGCTCGACCGGGTTTTCCGCCGCGCCAACGATACCTCTTTCAATGCCATCACCGTGGACG
GCGACATGTCCACCAACGATACCGCCATCATTATGGCCAACGGAGCAGCCGGCAACCCGGTTCTGTCCGAGGGGAGCGAG
GGCGCCGCGGAATTTGCTGTTCTTTTGGAGGAGGTGCTCCTCTCTCTGGCCAAGCTGATCGTCAAGGATGGAGAAGGGGC
CACCAAGTTTGTGGAAGTAACCGTGAAGGGTGCCCGCTCCGATGCCGACGCCAAGCGGGCCGCCATGGCCGTCGCCAATT
CATGCCTGGTGAAGACCGCCTTTTTCGGGCAGGATGCCAACTGGGGGCGGATTTTCGCGGCGGTGGGCTACTCCGGCGCG
GACGTGGAACCGGACCGTGCCGAGCTGTTTTTCGACGATGTCAGGATGGTACAGGGTGGTGTTTTCGCAGGCGGCGACGC
TGAGGCGCGGGGTACCGGGGTATTGCGGAAGAAGGAGTTCACCGTTACTGTAGACCTGCATCTGGGCGACGGACGGGCAA
CGGTTTACACCTCGGACCTGTCCTACGACTACGTCAAGATCAACGCCGATTACCGTACCTGA

Upstream 100 bases:

>100_bases
CTGCGGTAGCGGCAAGAAGTACAAGAAGTGCTGCGGAAAATGAGATAGCTTAGGAAGGCGCCGGGTTCTCAGGTTGTGGC
GCTCTCATGAGGTTTCAGTT

Downstream 100 bases:

>100_bases
GGAGCAGAGGGGTGTCGAACAACACCAAAAACAGGAGAGGGAGGTGGTGCGGATGCTGAGACTGGTCGTCCTGCTCGTTG
CGCTAGTTGCGTGCGGCATG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNVKGFRFSAVEAAIKKPGRLDLALICSDAPAAVAAVYTTNKVKAAPVLLDMERTTSGTCRAVVVNSGNANACTGDRGME
DARETTSLVAERIGASEHEVLVCSTGVIGVPLPMERIRGGIPSLVAGLGSATLDQIAAAIMTTDTFPKLEARTGTAGGVG
YTIAGIAKGAGMIMPNMATMLAFVVTDAAVDPQWLDRVFRRANDTSFNAITVDGDMSTNDTAIIMANGAAGNPVLSEGSE
GAAEFAVLLEEVLLSLAKLIVKDGEGATKFVEVTVKGARSDADAKRAAMAVANSCLVKTAFFGQDANWGRIFAAVGYSGA
DVEPDRAELFFDDVRMVQGGVFAGGDAEARGTGVLRKKEFTVTVDLHLGDGRATVYTSDLSYDYVKINADYRT

Sequences:

>Translated_393_residues
MNVKGFRFSAVEAAIKKPGRLDLALICSDAPAAVAAVYTTNKVKAAPVLLDMERTTSGTCRAVVVNSGNANACTGDRGME
DARETTSLVAERIGASEHEVLVCSTGVIGVPLPMERIRGGIPSLVAGLGSATLDQIAAAIMTTDTFPKLEARTGTAGGVG
YTIAGIAKGAGMIMPNMATMLAFVVTDAAVDPQWLDRVFRRANDTSFNAITVDGDMSTNDTAIIMANGAAGNPVLSEGSE
GAAEFAVLLEEVLLSLAKLIVKDGEGATKFVEVTVKGARSDADAKRAAMAVANSCLVKTAFFGQDANWGRIFAAVGYSGA
DVEPDRAELFFDDVRMVQGGVFAGGDAEARGTGVLRKKEFTVTVDLHLGDGRATVYTSDLSYDYVKINADYRT
>Mature_393_residues
MNVKGFRFSAVEAAIKKPGRLDLALICSDAPAAVAAVYTTNKVKAAPVLLDMERTTSGTCRAVVVNSGNANACTGDRGME
DARETTSLVAERIGASEHEVLVCSTGVIGVPLPMERIRGGIPSLVAGLGSATLDQIAAAIMTTDTFPKLEARTGTAGGVG
YTIAGIAKGAGMIMPNMATMLAFVVTDAAVDPQWLDRVFRRANDTSFNAITVDGDMSTNDTAIIMANGAAGNPVLSEGSE
GAAEFAVLLEEVLLSLAKLIVKDGEGATKFVEVTVKGARSDADAKRAAMAVANSCLVKTAFFGQDANWGRIFAAVGYSGA
DVEPDRAELFFDDVRMVQGGVFAGGDAEARGTGVLRKKEFTVTVDLHLGDGRATVYTSDLSYDYVKINADYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=413, Percent_Identity=42.8571428571429, Blast_Score=297, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_GEOSL (P62061)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953098.1
- ProteinModelPortal:   P62061
- SMR:   P62061
- MEROPS:   T05.001
- GeneID:   2686046
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2049
- NMPDR:   fig|243231.1.peg.2036
- TIGR:   GSU2049
- HOGENOM:   HBG284202
- OMA:   VHENSAY
- ProtClustDB:   PRK05388
- BioCyc:   GSUL243231:GSU_2049-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 40986; Mature: 40986

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKGFRFSAVEAAIKKPGRLDLALICSDAPAAVAAVYTTNKVKAAPVLLDMERTTSGTC
CCCCCEEHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCEECEEEEEECCCCCCCE
RAVVVNSGNANACTGDRGMEDARETTSLVAERIGASEHEVLVCSTGVIGVPLPMERIRGG
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCHHHHCCC
IPSLVAGLGSATLDQIAAAIMTTDTFPKLEARTGTAGGVGYTIAGIAKGAGMIMPNMATM
CHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCEECCCHHHH
LAFVVTDAAVDPQWLDRVFRRANDTSFNAITVDGDMSTNDTAIIMANGAAGNPVLSEGSE
HHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
GAAEFAVLLEEVLLSLAKLIVKDGEGATKFVEVTVKGARSDADAKRAAMAVANSCLVKTA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHEEEE
FFGQDANWGRIFAAVGYSGADVEPDRAELFFDDVRMVQGGVFAGGDAEARGTGVLRKKEF
ECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEE
TVTVDLHLGDGRATVYTSDLSYDYVKINADYRT
EEEEEEEECCCCEEEEEECCCEEEEEEECCCCC
>Mature Secondary Structure
MNVKGFRFSAVEAAIKKPGRLDLALICSDAPAAVAAVYTTNKVKAAPVLLDMERTTSGTC
CCCCCEEHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCEECEEEEEECCCCCCCE
RAVVVNSGNANACTGDRGMEDARETTSLVAERIGASEHEVLVCSTGVIGVPLPMERIRGG
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCHHHHCCC
IPSLVAGLGSATLDQIAAAIMTTDTFPKLEARTGTAGGVGYTIAGIAKGAGMIMPNMATM
CHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCEECCCHHHH
LAFVVTDAAVDPQWLDRVFRRANDTSFNAITVDGDMSTNDTAIIMANGAAGNPVLSEGSE
HHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
GAAEFAVLLEEVLLSLAKLIVKDGEGATKFVEVTVKGARSDADAKRAAMAVANSCLVKTA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHEEEE
FFGQDANWGRIFAAVGYSGADVEPDRAELFFDDVRMVQGGVFAGGDAEARGTGVLRKKEF
ECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEE
TVTVDLHLGDGRATVYTSDLSYDYVKINADYRT
EEEEEEEECCCCEEEEEECCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA