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The map label for this gene is atoS [H]

Identifier: 39997039

GI number: 39997039

Start: 2124642

End: 2126675

Strand: Reverse

Name: atoS [H]

Synonym: GSU1941

Alternate gene names: 39997039

Gene position: 2126675-2124642 (Counterclockwise)

Preceding gene: 39997040

Following gene: 39997038

Centisome position: 55.76

GC content: 60.67

Gene sequence:

>2034_bases
ATGCAGTTGGTCCTTTCAGCGGCGGCGGTACTGCTCTCCCTGGCCGTAATCGGAGTCACCATCCGCCGTCAGGGGCTTAC
CCTTTCAGTCTGCGCGACAGTTGCCGCCCTGACGGCGGCTTCGGCTCTCGAAGTCTTGGACCTTGTCGTAATGCTCGACC
CGGATCGACTGTTTGAATGGAAACGGTGGGTTCTGGGGGTCGAATCCCTTTTGCCTGCGGCTTGGCTTACCTATAGCCTC
ACCCACTCCCGGCGGACTGCGACATCTGCTGTGCCCCGGTTGCAGCGGTTTTTCCTGGCCGCTACGGCTGCGTTCCCACT
GGCCGCTCTGCTGCTGCCGCCGGAGGTTTTCTTCTATTCACCGGATTTCGCCACGGAGCGGGTCCTGTTTCTGACGGTTC
ACGGCTACTACTTTTATCTCGGCCTGCTTCTCTTTGCTGTGATTTCCCTCGTCAATCTGGAGGGGACGTATTCTCATGCC
TCTCTCCTGGAGCGCTGGCGAATCAAATTCGATTTCATCGGCGCGACCAGTTACCTTGCGCTTCTGGTGCTCTACTACAG
CCAGGGGCTGCTCCATCGCTCTCTCAACATGGGGCTGTTGCCGGTACGATCCCTGATTCTTGCCCTTGCCGCTGCCATGA
TGCTCTATTCGCTCCTCGCACGGGGCAGCGGCGTGCGAATCGCGGTCTCGCGGAACATGGCCTACAAGTCGGTGGTGCTG
GTTGCCGTAGGGCTGTACCTGGTTGCCGTGGGGGTGATGGGGGAGGGGTTGCGCTACTTCGGGGAAGGCTTCCCCAAGGC
AATGGCCATTGCCGCCCTGTTCTGCATGGGCATTGCCCTGGTGGTCATTCTCTTGTCAGAGACCCTGCGCCGCAGGGTCC
GGGTCTTCATTCACAAGAATTTTTACCGGAGCAAGTACGATTACCAGACCCAGTGGCTCCACTTCACCGACCTGTTGGCC
TCTGCCCGCAGCTCTGACGGTCTCATGGAGGCAATCCTCGCCGGCTACAGCGGGGTTTTCGGCATGAACAGCGGAGTTCT
TTTCCTTAAAAGCGGAGACGACGGCTTATTCCGCTGGGCCGTCGCTCGGGAGCAGGCGCTGGCCGGTGCATTTTTCTCAT
CTAACGATCCTCCGGTGCGCCGGATGGCGGATGAGGGCTGGATCGTCAATCTCCGCGAGGCAAACCCTGAGGAGTTCTCC
GGTGCCGGTGAGTTTGTGCGGGAGAACAACGTCGTATTCCTCATCCCTCTGTCGTCCGGCGAGGGGCTTGAGGGGATCGT
TGCCCTGGGACGACCCGTGCATGAGGGAGAGTTCTATCACTACGAAGATTACGACCTGATGAAGACCATGGCTCGCCAGG
CCGCATCGGCCCTCATGAACCTGCGCCTCTCCGAGGAACTGGCAAGCGCCCGGGAACTGGAAGTGATGGGGCGGGTATCG
ACGTTTATCATCCATGACCTCAAAAACCTGGTCTATACCCTGTCGCTTACCGTGGACAACGCCCGTGACCATATCGCCGA
TGCCGAATTCCAGGAAGACATGCTCGGCACCCTCGGCAATACGGTGAACCGGATGAAGCTGCTCATAGCCCGGTTGCGCG
GCCTGCCTGAGAAGCAGTCCCTCTGTTTCGAAGAGGTCGATCTCCTTCGACTTGCCGAGGAGAGCGCGGGGCTTGCCGGC
GGCCGGGGCAGCATCAGTGTCGGCGGATCTGCTGTTTCCGCCCGGGTCGACCGCGAGGAGATCCAGAAAGTGGTCGTGAA
CCTGGTGGTGAACGCCTTGGAGGCCACGGAAGGGAAGGGGCCGGTGGCGGTGGAGGTGGGCTGCGGCACCGCCCCTTACA
TCCGCGTGACCGATGCCGGCTGCGGTATCCCCGATGCGTTTCGTGCCCACCTGTTCTCGCCCTTCAGGACCACCAAGAAG
AAAGGGCTCGGCATCGGGCTCTACCAGTGTCGCCGGATCGTGGAGGCACACGGCGGGAGAATAGACGTGGAGAGTACGCC
CGGACAGGGTGCGATGTTTACGGTGTGGTTGTAA

Upstream 100 bases:

>100_bases
ATGGGGCACCCCCCGGTTCTCATGGACGTTAAGGGTATGTACGACCAGAACATGCTGCGGCAGGCGGGAATCCGCTTCTG
GAGGCTCTGAGCCGGTCATG

Downstream 100 bases:

>100_bases
GGGGGTAGGAGATTCCATGGAAAAACTGCTGATCGTCGACGACAACGAAGATATTCGCAAACAGCTGAAATGGGGCATCG
GCAAGGAGTACACGCTGTTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MQLVLSAAAVLLSLAVIGVTIRRQGLTLSVCATVAALTAASALEVLDLVVMLDPDRLFEWKRWVLGVESLLPAAWLTYSL
THSRRTATSAVPRLQRFFLAATAAFPLAALLLPPEVFFYSPDFATERVLFLTVHGYYFYLGLLLFAVISLVNLEGTYSHA
SLLERWRIKFDFIGATSYLALLVLYYSQGLLHRSLNMGLLPVRSLILALAAAMMLYSLLARGSGVRIAVSRNMAYKSVVL
VAVGLYLVAVGVMGEGLRYFGEGFPKAMAIAALFCMGIALVVILLSETLRRRVRVFIHKNFYRSKYDYQTQWLHFTDLLA
SARSSDGLMEAILAGYSGVFGMNSGVLFLKSGDDGLFRWAVAREQALAGAFFSSNDPPVRRMADEGWIVNLREANPEEFS
GAGEFVRENNVVFLIPLSSGEGLEGIVALGRPVHEGEFYHYEDYDLMKTMARQAASALMNLRLSEELASARELEVMGRVS
TFIIHDLKNLVYTLSLTVDNARDHIADAEFQEDMLGTLGNTVNRMKLLIARLRGLPEKQSLCFEEVDLLRLAEESAGLAG
GRGSISVGGSAVSARVDREEIQKVVVNLVVNALEATEGKGPVAVEVGCGTAPYIRVTDAGCGIPDAFRAHLFSPFRTTKK
KGLGIGLYQCRRIVEAHGGRIDVESTPGQGAMFTVWL

Sequences:

>Translated_677_residues
MQLVLSAAAVLLSLAVIGVTIRRQGLTLSVCATVAALTAASALEVLDLVVMLDPDRLFEWKRWVLGVESLLPAAWLTYSL
THSRRTATSAVPRLQRFFLAATAAFPLAALLLPPEVFFYSPDFATERVLFLTVHGYYFYLGLLLFAVISLVNLEGTYSHA
SLLERWRIKFDFIGATSYLALLVLYYSQGLLHRSLNMGLLPVRSLILALAAAMMLYSLLARGSGVRIAVSRNMAYKSVVL
VAVGLYLVAVGVMGEGLRYFGEGFPKAMAIAALFCMGIALVVILLSETLRRRVRVFIHKNFYRSKYDYQTQWLHFTDLLA
SARSSDGLMEAILAGYSGVFGMNSGVLFLKSGDDGLFRWAVAREQALAGAFFSSNDPPVRRMADEGWIVNLREANPEEFS
GAGEFVRENNVVFLIPLSSGEGLEGIVALGRPVHEGEFYHYEDYDLMKTMARQAASALMNLRLSEELASARELEVMGRVS
TFIIHDLKNLVYTLSLTVDNARDHIADAEFQEDMLGTLGNTVNRMKLLIARLRGLPEKQSLCFEEVDLLRLAEESAGLAG
GRGSISVGGSAVSARVDREEIQKVVVNLVVNALEATEGKGPVAVEVGCGTAPYIRVTDAGCGIPDAFRAHLFSPFRTTKK
KGLGIGLYQCRRIVEAHGGRIDVESTPGQGAMFTVWL
>Mature_677_residues
MQLVLSAAAVLLSLAVIGVTIRRQGLTLSVCATVAALTAASALEVLDLVVMLDPDRLFEWKRWVLGVESLLPAAWLTYSL
THSRRTATSAVPRLQRFFLAATAAFPLAALLLPPEVFFYSPDFATERVLFLTVHGYYFYLGLLLFAVISLVNLEGTYSHA
SLLERWRIKFDFIGATSYLALLVLYYSQGLLHRSLNMGLLPVRSLILALAAAMMLYSLLARGSGVRIAVSRNMAYKSVVL
VAVGLYLVAVGVMGEGLRYFGEGFPKAMAIAALFCMGIALVVILLSETLRRRVRVFIHKNFYRSKYDYQTQWLHFTDLLA
SARSSDGLMEAILAGYSGVFGMNSGVLFLKSGDDGLFRWAVAREQALAGAFFSSNDPPVRRMADEGWIVNLREANPEEFS
GAGEFVRENNVVFLIPLSSGEGLEGIVALGRPVHEGEFYHYEDYDLMKTMARQAASALMNLRLSEELASARELEVMGRVS
TFIIHDLKNLVYTLSLTVDNARDHIADAEFQEDMLGTLGNTVNRMKLLIARLRGLPEKQSLCFEEVDLLRLAEESAGLAG
GRGSISVGGSAVSARVDREEIQKVVVNLVVNALEATEGKGPVAVEVGCGTAPYIRVTDAGCGIPDAFRAHLFSPFRTTKK
KGLGIGLYQCRRIVEAHGGRIDVESTPGQGAMFTVWL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=29.0909090909091, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=27.8761061946903, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786912, Length=286, Percent_Identity=28.3216783216783, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74156; Mature: 74156

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLVLSAAAVLLSLAVIGVTIRRQGLTLSVCATVAALTAASALEVLDLVVMLDPDRLFEW
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHH
KRWVLGVESLLPAAWLTYSLTHSRRTATSAVPRLQRFFLAATAAFPLAALLLPPEVFFYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEC
PDFATERVLFLTVHGYYFYLGLLLFAVISLVNLEGTYSHASLLERWRIKFDFIGATSYLA
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEECHHHHHH
LLVLYYSQGLLHRSLNMGLLPVRSLILALAAAMMLYSLLARGSGVRIAVSRNMAYKSVVL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
VAVGLYLVAVGVMGEGLRYFGEGFPKAMAIAALFCMGIALVVILLSETLRRRVRVFIHKN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYRSKYDYQTQWLHFTDLLASARSSDGLMEAILAGYSGVFGMNSGVLFLKSGDDGLFRWA
HHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHH
VAREQALAGAFFSSNDPPVRRMADEGWIVNLREANPEEFSGAGEFVRENNVVFLIPLSSG
HHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCCHHHCCCHHHHCCCCEEEEEECCCC
EGLEGIVALGRPVHEGEFYHYEDYDLMKTMARQAASALMNLRLSEELASARELEVMGRVS
CCCCHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFIIHDLKNLVYTLSLTVDNARDHIADAEFQEDMLGTLGNTVNRMKLLIARLRGLPEKQS
HHHHHHHHHHHEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LCFEEVDLLRLAEESAGLAGGRGSISVGGSAVSARVDREEIQKVVVNLVVNALEATEGKG
HHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
PVAVEVGCGTAPYIRVTDAGCGIPDAFRAHLFSPFRTTKKKGLGIGLYQCRRIVEAHGGR
CEEEEECCCCCCEEEEECCCCCCCHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHCCCE
IDVESTPGQGAMFTVWL
EEECCCCCCCCEEEEEC
>Mature Secondary Structure
MQLVLSAAAVLLSLAVIGVTIRRQGLTLSVCATVAALTAASALEVLDLVVMLDPDRLFEW
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHH
KRWVLGVESLLPAAWLTYSLTHSRRTATSAVPRLQRFFLAATAAFPLAALLLPPEVFFYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEC
PDFATERVLFLTVHGYYFYLGLLLFAVISLVNLEGTYSHASLLERWRIKFDFIGATSYLA
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEECHHHHHH
LLVLYYSQGLLHRSLNMGLLPVRSLILALAAAMMLYSLLARGSGVRIAVSRNMAYKSVVL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
VAVGLYLVAVGVMGEGLRYFGEGFPKAMAIAALFCMGIALVVILLSETLRRRVRVFIHKN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYRSKYDYQTQWLHFTDLLASARSSDGLMEAILAGYSGVFGMNSGVLFLKSGDDGLFRWA
HHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHH
VAREQALAGAFFSSNDPPVRRMADEGWIVNLREANPEEFSGAGEFVRENNVVFLIPLSSG
HHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCCHHHCCCHHHHCCCCEEEEEECCCC
EGLEGIVALGRPVHEGEFYHYEDYDLMKTMARQAASALMNLRLSEELASARELEVMGRVS
CCCCHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFIIHDLKNLVYTLSLTVDNARDHIADAEFQEDMLGTLGNTVNRMKLLIARLRGLPEKQS
HHHHHHHHHHHEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LCFEEVDLLRLAEESAGLAGGRGSISVGGSAVSARVDREEIQKVVVNLVVNALEATEGKG
HHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
PVAVEVGCGTAPYIRVTDAGCGIPDAFRAHLFSPFRTTKKKGLGIGLYQCRRIVEAHGGR
CEEEEECCCCCCEEEEECCCCCCCHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHCCCE
IDVESTPGQGAMFTVWL
EEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]