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The map label for this gene is pyrH [H]

Identifier: 39997017

GI number: 39997017

Start: 2097801

End: 2098520

Strand: Reverse

Name: pyrH [H]

Synonym: GSU1919

Alternate gene names: 39997017

Gene position: 2098520-2097801 (Counterclockwise)

Preceding gene: 39997018

Following gene: 39997016

Centisome position: 55.02

GC content: 56.94

Gene sequence:

>720_bases
ATGGGTACACCCTACTACGGACGAGTGCTGCTTAAGCTTTCCGGTGAAGCCCTGGCCGGCGATCAGGGATACGGTATCGA
TCCCCGAACCATTACCGCCATTGCTGCCGAGATTAAGGAAGTTGTGGCCACCGGCTCTCAACTGGCCTTGGTGATCGGCG
GCGGTAACATCTTCCGCGGTCTTGCCGCATCTTCCAAGGGAATGGACCGCGCTAGCGCCGACTACATGGGCATGCTTGCG
ACTATGATCAACTCTCTGGCGATGCAGGATGCTCTAGAGAAGGTCGGTGTCGACACGCGAGTCCAGTCGGCCATCGCCAT
GCAGGAAGTGGCGGAGCCCTACATCAGGAGGCGGGCCATCCGCCATCTGGAGAAGGGGCGAATCGTTATTTTCGGCGCCG
GGACCGGTAATCCCTACTTTACGACCGACACGGCTGCAAGTCTGAGGGCCATGGAAATCGGGGCAGACGTCATTCTCAAG
GGGACCAAGGTCGACGGCGTCTATTCGGCCGACCCCAAGAAAGATCCGACTGCAATAAAGTACCCCCGGCTTACCTACCT
CGAGGTGCTCAAGAAGGGGCTTCAGGTGATGGACGCCACGGCAACATCGCTCTGCATGGACAATAATCTTCCCATCATCG
TGTTTGATATCACCACCTACGGCAATATCAAGAAAGTGGTGTGCGGCGAAGAGATCGGCACCATTGTGAAAGGAGAATGA

Upstream 100 bases:

>100_bases
GTCTGTAGCAAGGCACACGGGCCGGTCATGAACATGGCCGGCTCTTTTTGCGTTCGCGCCGACAGCGGCGCTTTAACAGC
GTGTACGAGGACAGAACATC

Downstream 100 bases:

>100_bases
CATGACGAAAGACGTCATCAACGATATGAAGTCTCACATGGAAAAATCGGTCGAATCGTTGCGTCGCGAGTACCAAAAAG
TTCGCACCGGTCGGGCAAAC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MGTPYYGRVLLKLSGEALAGDQGYGIDPRTITAIAAEIKEVVATGSQLALVIGGGNIFRGLAASSKGMDRASADYMGMLA
TMINSLAMQDALEKVGVDTRVQSAIAMQEVAEPYIRRRAIRHLEKGRIVIFGAGTGNPYFTTDTAASLRAMEIGADVILK
GTKVDGVYSADPKKDPTAIKYPRLTYLEVLKKGLQVMDATATSLCMDNNLPIIVFDITTYGNIKKVVCGEEIGTIVKGE

Sequences:

>Translated_239_residues
MGTPYYGRVLLKLSGEALAGDQGYGIDPRTITAIAAEIKEVVATGSQLALVIGGGNIFRGLAASSKGMDRASADYMGMLA
TMINSLAMQDALEKVGVDTRVQSAIAMQEVAEPYIRRRAIRHLEKGRIVIFGAGTGNPYFTTDTAASLRAMEIGADVILK
GTKVDGVYSADPKKDPTAIKYPRLTYLEVLKKGLQVMDATATSLCMDNNLPIIVFDITTYGNIKKVVCGEEIGTIVKGE
>Mature_238_residues
GTPYYGRVLLKLSGEALAGDQGYGIDPRTITAIAAEIKEVVATGSQLALVIGGGNIFRGLAASSKGMDRASADYMGMLAT
MINSLAMQDALEKVGVDTRVQSAIAMQEVAEPYIRRRAIRHLEKGRIVIFGAGTGNPYFTTDTAASLRAMEIGADVILKG
TKVDGVYSADPKKDPTAIKYPRLTYLEVLKKGLQVMDATATSLCMDNNLPIIVFDITTYGNIKKVVCGEEIGTIVKGE

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=54.0772532188841, Blast_Score=253, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25486; Mature: 25355

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTPYYGRVLLKLSGEALAGDQGYGIDPRTITAIAAEIKEVVATGSQLALVIGGGNIFRG
CCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHH
LAASSKGMDRASADYMGMLATMINSLAMQDALEKVGVDTRVQSAIAMQEVAEPYIRRRAI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RHLEKGRIVIFGAGTGNPYFTTDTAASLRAMEIGADVILKGTKVDGVYSADPKKDPTAIK
HHHHCCCEEEEECCCCCCEEECCHHHHHHHEEECCEEEEECCEECCEECCCCCCCCCCCC
YPRLTYLEVLKKGLQVMDATATSLCMDNNLPIIVFDITTYGNIKKVVCGEEIGTIVKGE
CCCHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCEEEEEECHHHCCEECCC
>Mature Secondary Structure 
GTPYYGRVLLKLSGEALAGDQGYGIDPRTITAIAAEIKEVVATGSQLALVIGGGNIFRG
CCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHH
LAASSKGMDRASADYMGMLATMINSLAMQDALEKVGVDTRVQSAIAMQEVAEPYIRRRAI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RHLEKGRIVIFGAGTGNPYFTTDTAASLRAMEIGADVILKGTKVDGVYSADPKKDPTAIK
HHHHCCCEEEEECCCCCCEEECCHHHHHHHEEECCEEEEECCEECCEECCCCCCCCCCCC
YPRLTYLEVLKKGLQVMDATATSLCMDNNLPIIVFDITTYGNIKKVVCGEEIGTIVKGE
CCCHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCEEEEEECHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA