Click here to switch to the map view.

The map label for this gene is frr

Identifier: 39997016

GI number: 39997016

Start: 2097242

End: 2097799

Strand: Reverse

Name: frr

Synonym: GSU1918

Alternate gene names: 39997016

Gene position: 2097799-2097242 (Counterclockwise)

Preceding gene: 39997017

Following gene: 39997015

Centisome position: 55.0

GC content: 53.23

Gene sequence:

>558_bases
ATGACGAAAGACGTCATCAACGATATGAAGTCTCACATGGAAAAATCGGTCGAATCGTTGCGTCGCGAGTACCAAAAAGT
TCGCACCGGTCGGGCAAACACCGGTCTTCTTGACGAGATCAGGGTGGATTTCTACGGTAACCCGTCTCCGCTCAACCAGG
TAGCTACTCTTGCCGTACCCGAGCCGCGGACCATCACCATTCAGCCGTGGGAGACAAAGATGATCCCGGTCATCGAGAAG
GCGATCCTGAACGCCAACCTCGGCTTCACCCCGTCCAATGACGGTAAGCTCATCCGGATCAGCCTTCCCCCCCTCACCGA
GGAACGTCGTAAAGAAATCGTGAAGTCGCTTAAAAAGACGGCTGAGGATGCCAAGATAGCCATTCGGAACATCCGTCGAG
ACGCCATTGATGGTCTCAAGAAGCTGGAGAAGGACAAAAAGATATCCGAAGACGACCTCAAGCGCGCCGAGAAGGAAGTC
CAGGATGTGACGAACGTCTATGTCGCCAAAGTTGATGAGGTCCTGGCACACAAGGAAAAGGAAGTCATGGAGGTGTGA

Upstream 100 bases:

>100_bases
AATAATCTTCCCATCATCGTGTTTGATATCACCACCTACGGCAATATCAAGAAAGTGGTGTGCGGCGAAGAGATCGGCAC
CATTGTGAAAGGAGAATGAC

Downstream 100 bases:

>100_bases
GGAGGCGTGGCCAATGGCCGCGCAACCTGTTAATTTCGTTTTTTTCCTTGCGCCCATACTGCTTTTATGGTTTAATCCCC
TTTAACCCCTCGTTTAAAGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTKDVINDMKSHMEKSVESLRREYQKVRTGRANTGLLDEIRVDFYGNPSPLNQVATLAVPEPRTITIQPWETKMIPVIEK
AILNANLGFTPSNDGKLIRISLPPLTEERRKEIVKSLKKTAEDAKIAIRNIRRDAIDGLKKLEKDKKISEDDLKRAEKEV
QDVTNVYVAKVDEVLAHKEKEVMEV

Sequences:

>Translated_185_residues
MTKDVINDMKSHMEKSVESLRREYQKVRTGRANTGLLDEIRVDFYGNPSPLNQVATLAVPEPRTITIQPWETKMIPVIEK
AILNANLGFTPSNDGKLIRISLPPLTEERRKEIVKSLKKTAEDAKIAIRNIRRDAIDGLKKLEKDKKISEDDLKRAEKEV
QDVTNVYVAKVDEVLAHKEKEVMEV
>Mature_184_residues
TKDVINDMKSHMEKSVESLRREYQKVRTGRANTGLLDEIRVDFYGNPSPLNQVATLAVPEPRTITIQPWETKMIPVIEKA
ILNANLGFTPSNDGKLIRISLPPLTEERRKEIVKSLKKTAEDAKIAIRNIRRDAIDGLKKLEKDKKISEDDLKRAEKEVQ
DVTNVYVAKVDEVLAHKEKEVMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=186, Percent_Identity=29.5698924731183, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=31.3333333333333, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=45.6521739130435, Blast_Score=176, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=26.8156424581006, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_GEOSL (P61304)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952967.1
- ProteinModelPortal:   P61304
- SMR:   P61304
- GeneID:   2685328
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1918
- NMPDR:   fig|243231.1.peg.1905
- TIGR:   GSU1918
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   GSUL243231:GSU_1918-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21117; Mature: 20985

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDVINDMKSHMEKSVESLRREYQKVRTGRANTGLLDEIRVDFYGNPSPLNQVATLAVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHHHHEECC
EPRTITIQPWETKMIPVIEKAILNANLGFTPSNDGKLIRISLPPLTEERRKEIVKSLKKT
CCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
AEDAKIAIRNIRRDAIDGLKKLEKDKKISEDDLKRAEKEVQDVTNVYVAKVDEVLAHKEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVMEV
HHHCC
>Mature Secondary Structure 
TKDVINDMKSHMEKSVESLRREYQKVRTGRANTGLLDEIRVDFYGNPSPLNQVATLAVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHHHHEECC
EPRTITIQPWETKMIPVIEKAILNANLGFTPSNDGKLIRISLPPLTEERRKEIVKSLKKT
CCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
AEDAKIAIRNIRRDAIDGLKKLEKDKKISEDDLKRAEKEVQDVTNVYVAKVDEVLAHKEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA