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The map label for this gene is kdsB [H]

Identifier: 39996994

GI number: 39996994

Start: 2073902

End: 2074666

Strand: Reverse

Name: kdsB [H]

Synonym: GSU1896

Alternate gene names: 39996994

Gene position: 2074666-2073902 (Counterclockwise)

Preceding gene: 39996996

Following gene: 39996993

Centisome position: 54.39

GC content: 59.35

Gene sequence:

>765_bases
ATGGGACTTCGTATGAACATCACCGCCATAATCCCCGCCCGTTTCGCGTCGACCCGCTTTCCCGGCAAGGCTCTGGCCGA
CATTGCGGGCAAGCCGATGGTTCAGCATGTGTATGAGCGTACCGCCCGGGCACGTCTTGTGTCTGAGGTTGTCGTGGCAA
CGGATGATGACCGGATCGCCCAGGCGGTCCGCGGCTTCGGCGGCAGGGTCGAAATGACCTCCCGGGACCACGAGACGGGA
ACGGATCGTCTCGCCGAGGTGGCCTCGCGCATCGGGGCCGAGATCATCGTGAACGTGCAGGGTGATGAACCGCTCATTGA
GCCCGCCATGATCGACGAGGCGATTGCTCCGCTTGCGGAGAATCCTGCCGTTCGCATGGGTACCCTCAAGAGCCGCATCC
GGACGCTCCACGACTTTCTGAGTCCCAACGTCGTGAAGGTTGTGACTGATCTGGAGGGGTATGCGCTCTACTTCTCCCGT
TCGCCGCTTCCTTTTTTCAGGGACAAGTGGAATGACTTGAAAGACGAGTCCTTTGCATCGGGGCGGCTGCTCTGCTACAA
GCATGTGGGGCTCTATGTCTATCGACGCGATTTCCTTATGGAGTTCGCAAAAATGCCACCCACCGCCCTCGAGTTGGCGG
AAAAACTCGAACAGCTCCGGGCGCTGGAGAACGGCTGCCGGATCAGGGTGGTTGAAACAGCGCACGAGTCGATCGGCGTC
GACACCCCCAACGACCTGGAAAAGGTTCTCGAAAAGTTGAAATAA

Upstream 100 bases:

>100_bases
GTTAATCTCGTCGGTAACGTCATTTCAACCAGTTGCACGTTTCGCCCCCACAGGGTGCGTGGCGTTCGCGCATGCCGTTC
AGGGCGAGTGCAGTATGTGA

Downstream 100 bases:

>100_bases
TCTGACTCAGGAGTGTGCATGAAAACCAAGTTCATCTTCGTAACCGGTGGCGTTGTGTCCTCCATCGGCAAAGGGCTTGC
CTCGGCGTCGCTCGGGGCGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MGLRMNITAIIPARFASTRFPGKALADIAGKPMVQHVYERTARARLVSEVVVATDDDRIAQAVRGFGGRVEMTSRDHETG
TDRLAEVASRIGAEIIVNVQGDEPLIEPAMIDEAIAPLAENPAVRMGTLKSRIRTLHDFLSPNVVKVVTDLEGYALYFSR
SPLPFFRDKWNDLKDESFASGRLLCYKHVGLYVYRRDFLMEFAKMPPTALELAEKLEQLRALENGCRIRVVETAHESIGV
DTPNDLEKVLEKLK

Sequences:

>Translated_254_residues
MGLRMNITAIIPARFASTRFPGKALADIAGKPMVQHVYERTARARLVSEVVVATDDDRIAQAVRGFGGRVEMTSRDHETG
TDRLAEVASRIGAEIIVNVQGDEPLIEPAMIDEAIAPLAENPAVRMGTLKSRIRTLHDFLSPNVVKVVTDLEGYALYFSR
SPLPFFRDKWNDLKDESFASGRLLCYKHVGLYVYRRDFLMEFAKMPPTALELAEKLEQLRALENGCRIRVVETAHESIGV
DTPNDLEKVLEKLK
>Mature_253_residues
GLRMNITAIIPARFASTRFPGKALADIAGKPMVQHVYERTARARLVSEVVVATDDDRIAQAVRGFGGRVEMTSRDHETGT
DRLAEVASRIGAEIIVNVQGDEPLIEPAMIDEAIAPLAENPAVRMGTLKSRIRTLHDFLSPNVVKVVTDLEGYALYFSRS
PLPFFRDKWNDLKDESFASGRLLCYKHVGLYVYRRDFLMEFAKMPPTALELAEKLEQLRALENGCRIRVVETAHESIGVD
TPNDLEKVLEKLK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=255, Percent_Identity=45.8823529411765, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28424; Mature: 28293

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRMNITAIIPARFASTRFPGKALADIAGKPMVQHVYERTARARLVSEVVVATDDDRIA
CCCEEEEEEEEHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QAVRGFGGRVEMTSRDHETGTDRLAEVASRIGAEIIVNVQGDEPLIEPAMIDEAIAPLAE
HHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
NPAVRMGTLKSRIRTLHDFLSPNVVKVVTDLEGYALYFSRSPLPFFRDKWNDLKDESFAS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHCCCCCCCCCCC
GRLLCYKHVGLYVYRRDFLMEFAKMPPTALELAEKLEQLRALENGCRIRVVETAHESIGV
CCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCC
DTPNDLEKVLEKLK
CCCHHHHHHHHHCC
>Mature Secondary Structure 
GLRMNITAIIPARFASTRFPGKALADIAGKPMVQHVYERTARARLVSEVVVATDDDRIA
CCEEEEEEEEHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QAVRGFGGRVEMTSRDHETGTDRLAEVASRIGAEIIVNVQGDEPLIEPAMIDEAIAPLAE
HHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
NPAVRMGTLKSRIRTLHDFLSPNVVKVVTDLEGYALYFSRSPLPFFRDKWNDLKDESFAS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHCCCCCCCCCCC
GRLLCYKHVGLYVYRRDFLMEFAKMPPTALELAEKLEQLRALENGCRIRVVETAHESIGV
CCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCC
DTPNDLEKVLEKLK
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA